scholarly journals The clinical use of indocyanine green as a near-infrared fluorescent contrast agent for image-guided oncologic surgery

2011 ◽  
Vol 104 (3) ◽  
pp. 323-332 ◽  
Author(s):  
Boudewijn E. Schaafsma ◽  
J. Sven D. Mieog ◽  
Merlijn Hutteman ◽  
Joost R. van der Vorst ◽  
Peter J.K. Kuppen ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Contrast Agent ◽  
Near Infrared ◽  
Clinical Use ◽  
Oncologic Surgery ◽  
Image Guided

scholarly journals Exploiting cyanine dye J-aggregates/monomer equilibrium in hydrophobic protein pockets for efficient multi-step phototherapy: An innovative concept for smart nanotheranostics

Nanoscale ◽  
2021 ◽  
Author(s):  
Matias Luis Picchio ◽  
Julian Bergueiro Álvarez ◽  
Stefanie Wedepohl ◽  
Roque J Minari ◽  
Cecilia Ines Alvarez Igarzabal ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Contrast Agent ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Cyanine Dye ◽  
Hydrophobic Protein ◽  
Nir Dyes ◽  
Protein Pockets ◽  
J Aggregates ◽  
Innovative Concept

After several decades of development in the field of near-infrared (NIR) dyes for photothermal therapy (PTT), indocyanine green (ICG) still remains the only FDA-approved NIR contrast agent. However, upon NIR...

scholarly journals Fluorescence image-guided lymphadenectomy using indocyanine green and near infrared technology in robotic gastrectomy

2018 ◽  
Vol 30 (5) ◽  
pp. 568-570 ◽  
Author(s):  
Jacopo Desiderio ◽  
◽  
Stefano Trastulli ◽  
Alessandro Gemini ◽  
Domenico Di Nardo ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Near Infrared ◽  
Robotic Gastrectomy ◽  
Fluorescence Image ◽  
Image Guided ◽  
Infrared Technology

scholarly journals Role of Indocyanine Green in Fluorescence Imaging with Near-Infrared Light to Identify Sentinel Lymph Nodes, Lymphatic Vessels and Pathways Prior to Surgery – A Critical Evaluation of Options

2018 ◽  
Vol 78 (01) ◽  
pp. 54-62 ◽  
Author(s):  
Andreas Hackethal ◽  
Markus Hirschburger ◽  
Sven Eicker ◽  
Thomas Mücke ◽  
Christoph Lindner ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Indocyanine Green ◽  
Functional Imaging ◽  
Near Infrared ◽  
Critical Evaluation ◽  
Surgical Techniques ◽  
Sentinel Lymph Nodes ◽  
Infrared Light ◽  
Oncologic Surgery ◽  
Detection Rates

AbstractModern surgical strategies aim to reduce trauma by using functional imaging to improve surgical outcomes. This reviews considers and evaluates the importance of the fluorescent dye indocyanine green (ICG) to visualize lymph nodes, lymphatic pathways and vessels and tissue borders in an interdisciplinary setting. The work is based on a selective search of the literature in PubMed, Scopus, and Google Scholar and the authorsʼ own clinical experience. Because of its simple, radiation-free and uncomplicated application, ICG has become an important clinical indicator in recent years. In oncologic surgery ICG is used extensively to identify sentinel lymph nodes with promising results. In some studies, the detection rates with ICG have been better than the rates obtained with established procedures. When ICG is used for visualization and the quantification of tissue perfusion, it can lead to fewer cases of anastomotic insufficiency or transplant necrosis. The use of ICG for the imaging of organ borders, flap plasty borders and postoperative vascularization has also been scientifically evaluated. Combining the easily applied ICG dye with technical options for intraoperative and interventional visualization has the potential to create new functional imaging procedures which, in future, could expand or even replace existing established surgical techniques, particularly the techniques used for sentinel lymph node and anastomosis imaging.

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