Iron oxide nanoparticles: a novel elicitor to enhance anticancer flavonoid production and gene expression in Dracocephalum kotschyi hairy‐root cultures

2019 ◽  
Vol 99 (14) ◽  
pp. 6418-6430 ◽  
Author(s):  
Elnaz Nourozi ◽  
Bahman Hosseini ◽  
Ramin Maleki ◽  
Babak Abdollahi Mandoulakani
Keyword(s):  
Gene Expression ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Hairy Root ◽  
Oxide Nanoparticles ◽  
Hairy Root Cultures ◽  
Root Cultures ◽  
Dracocephalum Kotschyi

scholarly journals An anisotropic nanocomposite hydrogel guides aligned orientation and enhances tenogenesis of human tendon stem/progenitor cells

2021 ◽  
Vol 9 (4) ◽  
pp. 1237-1245
Author(s):  
Yichi Xu ◽  
Heyong Yin ◽  
Jin Chu ◽  
David Eglin ◽  
Tiziano Serra ◽  
...  
Keyword(s):  
Gene Expression ◽  
Iron Oxide ◽  
Progenitor Cells ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Nanocomposite Hydrogel ◽  
Collagen Hydrogel ◽  
Human Tendon

An anisotropic magnetically-responsive collagen hydrogel loaded with iron oxide nanoparticles augments aligned cell row formation and tenogenic gene expression of tendon stem/progenitor cells.

A new biotechnological source of rosmarinic acid and surface flavonoids: Hairy root cultures of Dracocephalum kotschyi Boiss

2013 ◽  
Vol 50 ◽  
pp. 256-263 ◽  
Author(s):  
Mohammad Fattahi ◽  
Vahideh Nazeri ◽  
Laura Torras-Claveria ◽  
Fatemeh Sefidkon ◽  
Rosa M. Cusido ◽  
...  
Keyword(s):  
Hairy Root ◽  
Rosmarinic Acid ◽  
Hairy Root Cultures ◽  
Root Cultures ◽  
Dracocephalum Kotschyi

scholarly journals Synergistic Effect of Vitamin C with Superparamagnetic Iron Oxide Nanoparticles for Inhibiting Proliferation of Gastric Cancer Cells

2021 ◽  
Vol 12 (3) ◽  
pp. 3215-3224
Keyword(s):  
Gene Expression ◽  
Iron Oxide ◽  
Vitamin C ◽  
Iron Oxide Nanoparticles ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Dependent Manner ◽  
Low Doses ◽  
Gastric Cancer Cells

The present study aimed to explore the synergistic anticancer effect of combined L-ascorbic acid (LAA) with superparamagnetic iron oxide nanoparticles (SPIONs) on adenocarcinoma gastric cell line (AGS). Fe3O4-LAA was synthesized using the reverse co-precipitation technique. XRD, FT-IR, FESEM, and TEM were employed to characterize the synthesized nanoparticles. MTT test and Real-time PCR were performed to investigate the cytotoxicity and apoptosis induced by treatments. The present study indicated that the anticancer properties of vitamin C were increased when employed as the Fe3O4-LAA nanoparticles. A dose-dependent manner on the effect of Fe3O4-LAA on investigated genes was observed; p53 gene expression changes in high and low doses of Fe3O4-LAA were 7.4 and 3.1 fold, respectively; accordingly, Bcl2 gene expression under treatment with high and low doses of Fe3O4-LAA was reduced by 71% and 25%, respectively. In conclusion, our results indicated that Fe3O4-LAA nanoparticles might be an efficient agent for cancer treatment.

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