Evaluation of the effect of plant extracts and phenolic compounds on reduction of acrylamide in an asparagine/glucose model system by RP-HPLC-DAD

2009 ◽  
Vol 89 (10) ◽  
pp. 1674-1681 ◽  
Author(s):  
Fan Zhu ◽  
Yi-Zhong Cai ◽  
Jinxia Ke ◽  
Harold Corke
2005 ◽  
Vol 28 (9-10) ◽  
pp. 1005-1022 ◽  
Author(s):  
Pavel Jandera ◽  
Veronika Škeříková ◽  
Lucie Řehová ◽  
Tomáš Hájek ◽  
Lucie Baldriánová ◽  
...  

2006 ◽  
Vol 29 (2) ◽  
pp. 308-313 ◽  
Author(s):  
Dagmar Štěrbová ◽  
Jiří Vlček ◽  
Vlastimil Kubáň

1999 ◽  
Vol 47 (10) ◽  
pp. 3954-3962 ◽  
Author(s):  
Marja P. Kähkönen ◽  
Anu I. Hopia ◽  
Heikki J. Vuorela ◽  
Jussi-Pekka Rauha ◽  
Kalevi Pihlaja ◽  
...  

LWT ◽  
2019 ◽  
Vol 102 ◽  
pp. 173-180 ◽  
Author(s):  
Andressa Ladeira Bernardes ◽  
Juliana Almeida Moreira ◽  
Maria das Graças Vaz Tostes ◽  
Neuza Maria Brunoro Costa ◽  
Pollyanna Ibrahim Silva ◽  
...  

2018 ◽  
Vol 87 (2) ◽  
Author(s):  
Anita Agnieszka Śliwińska ◽  
Katarzyna Sykłowska-Baranek ◽  
Anita Kośmider ◽  
Sebastian Granica ◽  
Karolina Miszczak ◽  
...  

<p>In this study, an efficient method to enhance phenolic compound production in the in vitro cultured shoots of <em>Polyscias filicifolia</em> was developed. The phenolic compound content in <em>P. filicifolia</em> has not yet been reported. Shoots were treated with methyl jasmonate (JM) or salicylic acid (SA) at doses of 50, 100, or 200 µM. HPLC-UV-VIS and LC-MS techniques were used for the determination of chlorogenic, caffeic, and ferulic acids. The total phenolics and flavonoids were quantified, and the antioxidant capacity of plant extracts was determined using DPPH and ABTS methods. Finally, the cytotoxic activity of <em>P. filicifolia</em> extracts in normal (HaCaT) and cancer (A549) cells was investigated. Further, the effect of the extracts on cisplatin cytotoxicity was assessed.</p><p>The elicitors significantly enhanced phenolic production compared to that in untreated shoots and leaves of intact plants. Chlorogenic acid was the most abundant compound with the highest yield of 5.03 ±0.25 mg/g DW after treatment with 50 µM SA. The total flavonoid and phenolic content was significantly and dose-dependently influenced by JM. The highest antioxidant capacity was noted in extracts derived from shoots grown on media supplemented with 50 µM SA and 200 µM JM; these doses were used for further cytotoxic activity investigations. The extracts from JM or SA treatments reduced cancer cell viability and increased their mortality, whereas the extract from JM treatment exhibited protective effect on normal cells. Moreover, the comparison of cytotoxic properties of plant extracts and cisplatin indicated that plant phenolic compounds in combination with anticancer drugs could reduce the detrimental effect of the latter on human cells.</p>


2013 ◽  
Vol 19 (No. 4) ◽  
pp. 139-142 ◽  
Author(s):  
R. Amarowicz ◽  
M. Karamać ◽  
S. Weidner

An extract of seeds of pea was prepared using 80% (v/v) acetone. Six fractions (I&ndash;VI) were separated from the crude extract on a Sephadex LH-20 column using methanol as the mobile phase. The antioxidant activity of fractions was investigated in a &beta;-carotene-linoleate model system. For individual fractions, UV spectra were recorded and the content of total phenolics was determined. Results of the &beta;-carotene-linoleate model system indicated that antioxidant activities of separated fractions correlated with their content of total phenolic compounds and they decreased in the order of IV&nbsp;= VI &gt; V &gt; III &gt; I &gt; II. The antioxidant activity of fractions IV and VI was very strong as compared with that of butylated hydroxyanisole (BHA). Absorption maxima from UV spectra showed that flavonoids, and not phenolic acids, were the main phenolic compounds in separated fractions.


2018 ◽  
Vol 28 (2) ◽  
pp. 231-234 ◽  
Author(s):  
Thiruventhan Karunakaran ◽  
Intan Safinar Ismail ◽  
Gwendoline Cheng Lian Ee ◽  
Siti Mariam Mohd Nor ◽  
Kalaivani Palachandran ◽  
...  

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