Endogenous amino acid flow at the terminal ileum of adult humans determined following the ingestion of a single protein-free meal

1993 ◽  
Vol 61 (4) ◽  
pp. 439-442 ◽  
Author(s):  
Angela M Rowan ◽  
Paul J Moughan ◽  
Margaret N Wilson
Keyword(s):  
Amino Acid ◽  
Terminal Ileum ◽  
Adult Humans ◽  
Single Protein ◽  
Endogenous Amino Acid

Determination of endogenous amino acid flow at the terminal ileum of the rat

1988 ◽  
Vol 44 (3) ◽  
pp. 227-235 ◽  
Author(s):  
Grant A Skilton ◽  
Paul J Moughan ◽  
William C Smith
Keyword(s):  
Amino Acid ◽  
Terminal Ileum ◽  
Endogenous Amino Acid

Endogenous amino acid flows at the terminal ileum of broilers, layers and adult roosters

2004 ◽  
Vol 79 (2) ◽  
pp. 265-271 ◽  
Author(s):  
V. Ravindran ◽  
W. H. Hendriks
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Glutamic Acid ◽  
Terminal Ileum ◽  
Crude Protein ◽  
Amino Acid Profile ◽  
The Other ◽  
Endogenous Protein ◽  
Abundant Amino Acid ◽  
Endogenous Amino Acid

AbstractEndogenous flows of nitrogen and amino acids at the terminal ileum of broilers (6 weeks old), layers (70 weeks old) and adult roosters (70 weeks old) were determined using the peptide alimentation method. The ileal endogenous output of nitrogen and total amino acids in broilers, layers and roosters, expressed as mg/kg dry matter intake, were similar (F > 0-05). Endogenous flows were similar (F > 0-05) for nine of the 17 amino acids analysed, but the flows of serine, glutamic acid, proline, alanine, isoleucine, tyrosine, arginine and methionine differed (P < 0-05) among the classes of chickens. The amino acid profile of endogenous protein, expressed asg/100 g crude protein, did not differ (F > 0-05) between the three classes of chickens, except for serine, glutamic acid, proline and isoleucine. The concentrations of proline were higher (F < 0-05) in broilers, compared with the other two groups. The concentrations of glutamic acid in layers were lower (F < 0-05) than the other two groups. The concentrations of serine and isoleucine were higher (F < 0-05) in roosters than the other two groups. In all three groups, the most abundant amino acid in the ileal endogenous protein was glutamic acid, followed by aspartic acid, proline, serine, glycine and threonine. The present study provides estimates for endogenous amino acid flow at the terminal ileum in broilers, layers and adult roosters under normal physiological conditions.

scholarly journals Comparison of the ileal and faecal digestibility of dietary amino acids in adult humans and evaluation of the pig as a model animal for digestion studies in man

1994 ◽  
Vol 71 (1) ◽  
pp. 29-42 ◽  
Author(s):  
Angela M. Rowan ◽  
P. J. Moughan ◽  
M. N. Wilson ◽  
K. Maher ◽  
C. Tasman-Jones
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Terminal Ileum ◽  
Human Subjects ◽  
Growing Pigs ◽  
Microbial Colonization ◽  
Diaminopimelic Acid ◽  
Adult Human ◽  
Model Animal ◽  
Adult Humans

The aim of the study was to determine if there is a difference between ileal and faecal assays for determining amino acid and N digestibilities in adult human subjects. Comparison of true ileal amino acid and N digestibilities was also made between adult human subjects and growing pigs to establish the usefulness of the pig as a model animal. Five subjects with established ileostomies and six subjects with intact large bowels consumed a constant diet consisting of meat, vegetables, fruit, bread and dairy products for 7 d with collection of ileostomy contents or faeces respectively over the last 4 d. The study was repeated using 25 kg body weight ileostomized and intact pigs. Apparent amino acid and N digestibility coefficients were determined. For human subjects the faecal digestibility values were significantly higher (P < 0·05) than the ileal values for Arg, Asp, Gly, Phe, Pro, Ser, Thr and Trp. The faecal digestibility of Met was significantly lower than the ileal value. Determination of DNA, diaminopimelic acid (DAPA) and the digestibilities of pectin, hemicellulose and cellulose in human subjects indicated that some microbial colonization had occurred at the terminal ileum after formation of an ileostomy; however, this was not as extensive as in the large intestine. True ileal amino acid and N digestibilities were calculated after correcting for the endogenous contribution of amino acids at the terminal ileum determined using a protein-free diet. There were no significant differences between adult human subjects and pigs for true ileal dietary amino acid digestibility except for Thr, Phe, Cys and Met. There were no significant differences between adult humans and pigs for the ileal digestibility of dry matter and the faecal digestibility of gross energy.

The design and validation of a diet for studies of amino acid metabolism in adult humans

1990 ◽  
Vol 10 (12) ◽  
pp. 1353-1365 ◽  
Author(s):  
Gordon A. Zello ◽  
Paul B. Pencharz ◽  
Ronald O. Ball
Keyword(s):  
Amino Acid ◽  
Amino Acid Metabolism ◽  
Acid Metabolism ◽  
Adult Humans

Endogenous Amino Acid Release from Cultured Cerebellar Neuronal Cells: Effect of Tetanus Toxin on Glutamate Release

1989 ◽  
Vol 52 (4) ◽  
pp. 1229-1239 ◽  
Author(s):  
Bernard J. Vliet ◽  
Michèle Sebben ◽  
Aline Dumuis ◽  
Jacqueline Gabrion ◽  
Joël Bockaert ◽  
...  
Keyword(s):  
Amino Acid ◽  
Tetanus Toxin ◽  
Glutamate Release ◽  
Neuronal Cells ◽  
Amino Acid Release ◽  
Acid Release ◽  
Endogenous Amino Acid
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