Oral supplementation of sea cucumber and its hydrolysate mitigates ultraviolet A ‐induced photoaging in hairless mice

5-Aminolevulinic Acid-Based Photodynamic Therapy Pretreatment Mitigates Ultraviolet A-Induced Oxidative Photodamage

Oxidative Medicine and Cellular Longevity ◽

10.1155/2018/9420745 ◽

2018 ◽

Vol 2018 ◽

pp. 1-11 ◽

Cited By ~ 2

Author(s):

Hui Hua ◽

Jiawei Cheng ◽

Wenbo Bu ◽

Juan Liu ◽

Weiwei Ma ◽

...

Keyword(s):

Aminolevulinic Acid ◽

Epidermal Keratinocytes ◽

Control Group ◽

Hacat Cells ◽

Ultraviolet A ◽

Hairless Mice ◽

Human Epidermal Keratinocytes ◽

Experimental Group

Aim. To determine whether 5-aminolevulinic acid-based photodynamic therapy (ALA-PDT) is effective in combating ultraviolet A- (UVA-) induced oxidative photodamage of hairless mice skin in vivo and human epidermal keratinocytes in vitro. Methods. In in vitro experiments, the human keratinocyte cell line (HaCaT cells) was divided into two groups: the experimental group was treated with ALA-PDT and the control group was left untreated. Then, the experimental group and the control group of cells were exposed to 10 J/m2 of UVA radiation. ROS, O2− species, and MMP were determined by fluorescence microscopy; p53, OGG1, and XPC were determined by Western blot analysis; apoptosis was determined by flow cytometry; and 8-oxo-dG was determined by immunofluorescence. Moreover, HaCaT cells were also treated with ALA-PDT. Then, SOD1 and SOD2 were examined by Western blot analysis. In in vivo experiments, the dorsal skin of hairless mice was treated with ALA-PDT or saline-PDT, and then, they were exposed to 20 J/m2 UVA light. The compound 8-oxo-dG was detected by immunofluorescence. Conclusion. In human epidermal keratinocytes and hairless mice skin, UVA-induced oxidative damage can be prevented effectively with ALA-PDT pretreatment.

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Chronic exposure of Sk-1 hairless mice to narrow-band ultraviolet A (320-355 nm)

Photodermatology Photoimmunology & Photomedicine ◽

10.1111/j.1600-0781.1996.tb00236.x ◽

1996 ◽

Vol 12 (1) ◽

pp. 7-11 ◽

Cited By ~ 4

Author(s):

J. M. Menter ◽

R. M. Sayre ◽

A. A. Etemadi ◽

P. P. Agin ◽

I. Wills

Keyword(s):

Chronic Exposure ◽

Narrow Band ◽

Ultraviolet A ◽

Hairless Mice

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Ultraviolet A Radiation (320–400 nm) Protects Hairless Mice from Immunosuppression Induced by Ultraviolet B Radiation (280–320 nm) or Cis-Urocanic Acid

International Archives of Allergy and Immunology ◽

10.1159/000069463 ◽

1998 ◽

Vol 115 (4) ◽

pp. 316-322 ◽

Cited By ~ 81

Author(s):

V.E. Reeve ◽

M. Bosnic ◽

C. Boehm-Wilcox ◽

N. Nishimura ◽

R.D. Ley

Keyword(s):

Urocanic Acid ◽

Ultraviolet B ◽

Ultraviolet A ◽

Hairless Mice ◽

Ultraviolet B Radiation

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Ocular effects of treatment with various psoralen derivatives and ultraviolet-A(UVA) radiation in HRA/Skh hairless mice

Acta Ophthalmologica ◽

10.1111/j.1755-3768.1986.tb06955.x ◽

2009 ◽

Vol 64 (4) ◽

pp. 471-478 ◽

Cited By ~ 13

Author(s):

Felix M. Barker ◽

Pierrette Dayhaw-Barker ◽

P. Donald Forbes ◽

Ronald E. Davies

Keyword(s):

Ultraviolet A ◽

Hairless Mice ◽

Psoralen Derivatives ◽

Uva Radiation

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Chronic exposure of SK-1 hairless mice to narrow-band ultraviolet A (320-355 nm)

Photodermatology Photoimmunology & Photomedicine ◽

10.1111/j.1600-0781.1996.tb00205.x ◽

1996 ◽

Vol 12 (5) ◽

pp. 222-222

Author(s):

Menter JM ◽

Sayre RM ◽

AA Etemadi ◽

PP Agin ◽

I Willis ◽

...

Keyword(s):

Chronic Exposure ◽

Narrow Band ◽

Ultraviolet A ◽

Hairless Mice

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Treatment with topical khellin in combination with ultraviolet A or solar-simulated radiation is carcinogenic to lightly pigmented hairless mice

Photodermatology Photoimmunology & Photomedicine ◽

10.1111/j.1600-0781.1995.tb00170.x ◽

1995 ◽

Vol 11 (5-6) ◽

pp. 204-208 ◽

Cited By ~ 2

Author(s):

N. Bech-Thomsen ◽

H. C. Wulf

Keyword(s):

Ultraviolet A ◽

Hairless Mice

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EFFECTS OF CHRONIC EXPOSURE ULTRAVIOLET-A INCLUDING 2% ULTRAVIOLET-B ON FREE RADICAL REDUCTION SYSTEMS IN HAIRLESS MICE

Photochemistry and Photobiology ◽

10.1111/j.1751-1097.1991.tb02083.x ◽

1991 ◽

Vol 54 (5) ◽

pp. 737-740 ◽

Cited By ~ 30

Author(s):

Kazuhisa Maeda ◽

Masako Naganuma ◽

Minoru Fukuda

Keyword(s):

Free Radical ◽

Chronic Exposure ◽

Ultraviolet B ◽

Ultraviolet A ◽

Hairless Mice ◽

Radical Reduction

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Topical AC-11 abates actinic keratoses and early squamous cell cancers in hairless mice exposed to Ultraviolet A (UVA) radiation

Dermatology Online Journal ◽

10.5070/d3214026285 ◽

2015 ◽

Vol 21 (4) ◽

Author(s):

Julian M Mentor ◽

Amir Etemadi ◽

Abrienne M Patta ◽

Noah Scheinfeld

Keyword(s):

Squamous Cell ◽

Ultraviolet A ◽

Hairless Mice ◽

Actinic Keratoses ◽

Uva Radiation

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Ultrastructural changes in murine lymphoma cells exposed to ultraviolet-A radiation

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s042482010008482x ◽

1991 ◽

Vol 49 ◽

pp. 104-105

Author(s):

Delma P. Thomas ◽

Dianne E. Godar

Keyword(s):

Medical Devices ◽

Blood Cells ◽

White Blood Cells ◽

Consumer Products ◽

Ultrastructural Changes ◽

Ultraviolet A ◽

Uv Spectrum ◽

Lymphoma Cells ◽

Murine Lymphoma ◽

Transmission Electron

Ultraviolet radiation (UVR) from all three waveband regions of the UV spectrum, UVA (320-400 nm), UVB (290-320 nm), and UVC (200-290 nm), can be emitted by some medical devices and consumer products. Sunlamps can expose the blood to a considerable amount of UVR, particularly UVA and/or UVB. The percent transmission of each waveband through the epidermis to the dermis, which contains blood, increases in the order of increasing wavelength: UVC (10%) < UVB (20%) < UVA (30%). To investigate the effects of UVR on white blood cells, we chose transmission electron microscopy to examine the ultrastructure changes in L5178Y-R murine lymphoma cells.

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