Comparative evaluation for phytochemical composition and regulation of blood glucose, hepatic oxidative stress and insulin resistance in mice and HepG2 models of four typical Chinese dark teas

2021 ◽  
Author(s):  
Jiangxiong Zhu ◽  
Chuang Yu ◽  
Hui Zhou ◽  
Xueqing Chen ◽  
Xinlin Wei ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Insulin Resistance ◽  
Blood Glucose ◽  
Comparative Evaluation ◽  
Phytochemical Composition ◽  
Hepatic Oxidative Stress

Tartary buckwheat flavonoids ameliorate high fructose-induced insulin resistance and oxidative stress associated with the insulin signaling and Nrf2/HO-1 pathways in mice

2017 ◽  
Vol 8 (8) ◽  
pp. 2803-2816 ◽  
Author(s):  
Yuanyuan Hu ◽  
Zuoxu Hou ◽  
Ruokun Yi ◽  
Zhongming Wang ◽  
Peng Sun ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Insulin Resistance ◽  
Drinking Water ◽  
Insulin Signaling ◽  
Tartary Buckwheat ◽  
Hepatic Oxidative Stress ◽  
High Fructose ◽  
Flavonoid Fraction ◽  
And Oxidative Stress

The present study was conducted to explore the effects of a purified tartary buckwheat flavonoid fraction (TBF) on insulin resistance and hepatic oxidative stress in mice fed high fructose in drinking water (20%) for 8 weeks.

scholarly journals JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis, and Insulin Resistance in Obesity

Diabetes ◽  
2017 ◽  
Vol 66 (12) ◽  
pp. 2973-2986 ◽  
Author(s):  
Sara A. Litwak ◽  
Lokman Pang ◽  
Sandra Galic ◽  
Mariana Igoillo-Esteve ◽  
William J. Stanley ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Insulin Resistance ◽  
Hepatic Oxidative Stress ◽  
Jnk Activation

scholarly journals Beneficial Effects of Poplar Buds on Hyperglycemia, Dyslipidemia, Oxidative Stress, and Inflammation in Streptozotocin-Induced Type-2 Diabetes

2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Shiqin Peng ◽  
Ping Wei ◽  
Qun Lu ◽  
Rui Liu ◽  
Yue Ding ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Blood Glucose ◽  
Crude Extract ◽  
Liver Homogenate ◽  
Control Group ◽  
Diabetic Mice ◽  
Model Control

The effects of propolis on blood glucose regulation and the alleviation of various complications caused by diabetes have been widely studied. The main source of propolis in the northern temperate zone is poplar buds. However, there is limited research on the antidiabetic activity of poplar buds. In order to evaluate the effect of poplar buds on type-2 diabetes, crude extract and 50% fraction of poplar buds were used to feed streptozotocin-induced type-2 diabetic mice. The results showed that 50% fraction could increase insulin sensitivity and reduce insulin resistance, as well as decrease the levels of fasting blood glucose, glycated hemoglobin, and glycosylated serum proteins in diabetic mice. Compared with the model control group, the 50% fraction-treated group showed significant decreases of malondialdehyde (MDA) and increases of superoxide dismutase (SOD) in serum and liver homogenate. Moreover, 50% fraction could significantly decrease total cholesterol (TC), alleviate abnormal lipid metabolism, and enhance antioxidant capacity in the serum. For inflammatory factors, feeding of 50% fraction could also reduce the levels of interleukin 6 (IL-6), tumor necrosis factorα(TNF-α), monocyte chemotactic protein 1 (MCP-1), and cyclooxygenase-2 (COX-2) in liver homogenate. Taken together, our results suggest that crude extract and 50% fraction of poplar buds, particularly the latter, can decrease blood glucose levels and insulin resistance, and 50% fraction can significantly relieve dyslipidemia, oxidative stress, and inflammation caused by type-2 diabetes.

scholarly journals Effects of free fatty acid elevation on hepatic insulin resistance and hepatic oxidative stress

2009 ◽  
Vol 17 (23) ◽  
pp. 2405
Author(s):  
Yan Lu ◽  
Ping Han ◽  
Sheng Zhao ◽  
Yong-Yan Zhang ◽  
Bing He ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Insulin Resistance ◽  
Fatty Acid ◽  
Free Fatty Acid ◽  
Hepatic Insulin Resistance ◽  
Hepatic Oxidative Stress

scholarly journals Phytochemical Composition of Costus Afer Extract and Its Alleviation of Carbon Tetrachloride – induced Hepatic Oxidative Stress and Toxicity

2013 ◽  
Vol 2 (5) ◽  
pp. 120-126 ◽  
Author(s):  
Ukpabi Chibueze F. ◽  
Agbafor Kingsley N. ◽  
Ndukwe Okorie K. ◽  
Agwu Akuagwu ◽  
Nwachukwu Success N.
Keyword(s):  
Oxidative Stress ◽  
Carbon Tetrachloride ◽  
Phytochemical Composition ◽  
Hepatic Oxidative Stress ◽  
Costus Afer

scholarly journals A hypercaloric diet induces hepatic oxidative stress, infiltration of lymphocytes, and mitochondrial reshuffle in Psammomys obesus, a murine model of insulin resistance

2019 ◽  
Vol 342 (5-6) ◽  
pp. 209-219 ◽  
Author(s):  
Ouahiba Sihali-Beloui ◽  
Djamila Aroune ◽  
Fella Benazouz ◽  
Adile Hadji ◽  
Salima El-Aoufi ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Insulin Resistance ◽  
Murine Model ◽  
Psammomys Obesus ◽  
Hepatic Oxidative Stress ◽  
Hypercaloric Diet
Sign in / Sign up

Export Citation Format

Share Document