Salt Effect on the Solution Properties of Cationic Gemini/Conventional Surfactants in the Presence of the Nonionic Polymer Hydroxypropylmethyl Cellulose

2019 ◽  
Vol 22 (6) ◽  
pp. 1279-1288
Author(s):  
Prashant Bhardwaj ◽  
Mohammad Kamil ◽  
Manorama Panda
Keyword(s):  
Salt Effect ◽  
Solution Properties ◽  
Hydroxypropylmethyl Cellulose ◽  
Nonionic Polymer

scholarly journals Influence of hydroxypropylmethyl cellulose-sodium laurylsulfate interaction on rheological properties of the solution

2004 ◽  
Vol 58 (11) ◽  
pp. 521-525 ◽  
Author(s):  
Jelena Saletic ◽  
Verica Sovilj ◽  
Lidija Petrovic
Keyword(s):  
Rheological Properties ◽  
Pharmaceutical Formulations ◽  
Critical Aggregation Concentration ◽  
Saturation Point ◽  
Rotational Viscometer ◽  
Hydroxypropylmethyl Cellulose ◽  
Rheological Measurements ◽  
Nonionic Polymer ◽  
Linear Relationships ◽  
Viscosity Changes

Interactions between the polymers and surfactants in solution have widely been investigated because of their scientific and technological importance. These interactions can be utilized to modify the physicochemical properties of system in many food products, pharmaceutical formulations, personal care products, paints, pesticides, etc. Interaction between nonionic polymer - hydroxypropylmethyl cellulose (HPMC) and anionic surfactant - sodium laurylsulfate (SDS) in solution has been investigated in this paper by rheological measurements. Rheological measurements are performed by rotational viscometer at 20?C and changes of rheological characteristics of HPMC solutions (0.5-1.5%) with increasing SDS concentrations (0-4.0%) were determined. The results of these investigations showed that viscosity of the solution is dependant on HPMC-SDS interaction. At particular SDS concentration viscosity increases, reach maximum and after that decreases until reach constant value. From the viscosity changes the characteristic concentrations of SDS, critical aggregation concentration (cac) and polymer saturation point (psp), were determined. These concentrations are in linear relationships with HPMC concentrations. Rheological properties of the solution are strong influenced by HPMC-SDS interaction and exhibits more or less pronounced pseudoplastic behavior, which changes to Newtonian one after the psp has been reached.

scholarly journals Salt Effect on the Cloud Point Phenomenon of Amphiphilic Drug-Hydroxypropylmethyl Cellulose System

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Mohd. Sajid Ali ◽  
Dileep Kumar ◽  
Hamad A. Al-Lohedan
Keyword(s):  
Cloud Point ◽  
Sodium Salt ◽  
Salt Effect ◽  
Tricyclic Antidepressant ◽  
High Concentration ◽  
Hydroxypropylmethyl Cellulose ◽  
Amphiphilic Drug ◽  
Amphiphilic Drugs ◽  
Nortriptyline Hydrochloride

Effect of two amphiphilic drugs (tricyclic antidepressant, nortriptyline hydrochloride (NORT), and nonsteroidal anti-inflammatory drug, sodium salt of ibuprofen (IBF)) on the cloud point of biopolymer hydroxypropylmethyl cellulose (HPMC) was studied. Effect of NaCl was also seen on the CP of HPMC-drug system. CP of HPMC increases uniformly on increasing the (drug). Both drugs, though one being anionic (IBF) and other cationic (NORT), affect the CP in almost the same manner but with different extent implying the role of hydrophobicity in the interaction between drug and polymer. Salt affects the CP of the drug in a dramatic way as low concentration of salt was only able to increase the value of the CP, though not affecting the pattern. However, in presence of high concentration of salts, minimum was observed on CP versus (drug) plots. Various thermodynamic parameters were evaluated and discussed on the basis of the observed results.

Solution properties of ionomers. 2. Simple salt effect

1989 ◽  
Vol 22 (2) ◽  
pp. 754-757 ◽  
Author(s):  
M. Hara ◽  
J. Wu ◽  
A. H. Lee
Keyword(s):  
Salt Effect ◽  
Solution Properties

Metallic Salt Effect on Polymer Oxidation

1952 ◽  
Vol 44 (3) ◽  
pp. 444-444
Author(s):  
N Chalapathi Rao ◽  
Hugh Winn ◽  
J Shelton
Keyword(s):  
Salt Effect ◽  
Metallic Salt ◽  
Polymer Oxidation

Solution Properties and Phase Behavior of Ammonium Hexylene Octyl Succinate in Water and Water-Oil System

1970 ◽  
Vol 3 (1) ◽  
Author(s):  
Md. Hamidul Kabir ◽  
Ravshan Makhkamov ◽  
Shaila Kabir
Keyword(s):  
Critical Micelle Concentration ◽  
Phase Behavior ◽  
Liquid Crystalline ◽  
Carbon Number ◽  
Phase Region ◽  
Solution Properties ◽  
Middle Phase ◽  
Two Phase ◽  
Lamellar Liquid Crystal ◽  
Drug Ingredient

The solution properties and phase behavior of ammonium hexylene octyl succinate (HOS) was investigated in water and water-oil system. The critical micelle concentration (CMC) of HOS is lower than that of anionic surfactants having same carbon number in the lipophilic part. The phase diagrams of a water/ HOS system and water/ HOS/ C10EO8/ dodecane system were also constructed. Above critical micelle concentration, the surfactant forms a normal micellar solution (Wm) at a low surfactant concentration whereas a lamellar liquid crystalline phase (La) dominates over a wide region through the formation of a two-phase region (La+W) in the binary system. The lamellar phase is arranged in the form of a biocompatible vesicle which is very significant for the drug delivery system. The surfactant tends to be hydrophilic when it is mixed with C10EO8 and a middle-phase microemulsion (D) is appeared in the water-surfactant-dodecane system where both the water and oil soluble drug ingredient can be incorporated in the form of a dispersion. Hence, mixing can tune the hydrophile-lipophile properties of the surfactant. Key words: Ammonium hexylene octyl succinate, mixed surfactant, lamellar liquid crystal, middle-phase microemulsion. Dhaka Univ. J. Pharm. Sci. Vol.3(1-2) 2004 The full text is of this article is available at the Dhaka Univ. J. Pharm. Sci. website

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