Gelation Process and Physicochemical Properties of Thai Silk Fibroin Hydrogels Induced by Various Anionic Surfactants for Controlled Release of Curcumin

2019 ◽  
Vol 22 (6) ◽  
pp. 1395-1407 ◽  
Author(s):  
Nattakan Chantong ◽  
Siriporn Damrongsakkul ◽  
Juthamas Ratanavaraporn
Keyword(s):  
Controlled Release ◽  
Physicochemical Properties ◽  
Silk Fibroin ◽  
Anionic Surfactants ◽  
Gelation Process

scholarly journals Is Dialdehyde Chitosan a Good Substance to Modify Physicochemical Properties of Biopolymeric Materials?

2021 ◽  
Vol 22 (7) ◽  
pp. 3391
Author(s):  
Sylwia Grabska-Zielińska ◽  
Alina Sionkowska ◽  
Ewa Olewnik-Kruszkowska ◽  
Katarzyna Reczyńska ◽  
Elżbieta Pamuła
Keyword(s):  
Mechanical Properties ◽  
Tissue Engineering ◽  
Physicochemical Properties ◽  
Silk Fibroin ◽  
Three Dimensional ◽  
Microscopy Imaging ◽  
Maximum Deformation ◽  
One Step ◽  
Chitosan Blends ◽  
Fourier Transfer Infrared Spectroscopy

The aim of this work was to compare physicochemical properties of three dimensional scaffolds based on silk fibroin, collagen and chitosan blends, cross-linked with dialdehyde starch (DAS) and dialdehyde chitosan (DAC). DAS was commercially available, while DAC was obtained by one-step synthesis. Structure and physicochemical properties of the materials were characterized using Fourier transfer infrared spectroscopy with attenuated total reflectance device (FTIR-ATR), swelling behavior and water content measurements, porosity and density observations, scanning electron microscopy imaging (SEM), mechanical properties evaluation and thermogravimetric analysis. Metabolic activity with AlamarBlue assay and live/dead fluorescence staining were performed to evaluate the cytocompatibility of the obtained materials with MG-63 osteoblast-like cells. The results showed that the properties of the scaffolds based on silk fibroin, collagen and chitosan can be modified by chemical cross-linking with DAS and DAC. It was found that DAS and DAC have different influence on the properties of biopolymeric scaffolds. Materials cross-linked with DAS were characterized by higher swelling ability (~4000% for DAS cross-linked materials; ~2500% for DAC cross-linked materials), they had lower density (Coll/CTS/30SF scaffold cross-linked with DAS: 21.8 ± 2.4 g/cm3; cross-linked with DAC: 14.6 ± 0.7 g/cm3) and lower mechanical properties (maximum deformation for DAC cross-linked scaffolds was about 69%; for DAS cross-linked scaffolds it was in the range of 12.67 ± 1.51% and 19.83 ± 1.30%) in comparison to materials cross-linked with DAC. Additionally, scaffolds cross-linked with DAS exhibited higher biocompatibility than those cross-linked with DAC. However, the obtained results showed that both types of scaffolds can provide the support required in regenerative medicine and tissue engineering. The scaffolds presented in the present work can be potentially used in bone tissue engineering to facilitate healing of small bone defects.

Silk fibroin double-layer microneedles for the encapsulation and controlled release of triptorelin

2021 ◽  
pp. 121433
Author(s):  
Xiaoyan Lu ◽  
Yiying Sun ◽  
Meishan Han ◽  
Daoyuan Chen ◽  
Aiping Wang ◽  
...  
Keyword(s):  
Controlled Release ◽  
Double Layer ◽  
Silk Fibroin

scholarly journals Effect of Physicochemical Properties in Water on Release Profile of Metominostrobin from Time-Controlled Release Granule

2001 ◽  
Vol 26 (3) ◽  
pp. 244-247 ◽  
Author(s):  
Shigeru TASHIMA ◽  
Shinji SHIMADA ◽  
Kohei MATSUMOTO ◽  
Reiji TAKEDA ◽  
Tomonori SHIRAISHI
Keyword(s):  
Controlled Release ◽  
Physicochemical Properties ◽  
Release Profile

Assessing the influence of silkworm cocoon’s age on the physicochemical properties of silk fibroin-based materials

2019 ◽  
Vol 34 (11) ◽  
pp. 1944-1949 ◽  
Author(s):  
Silvia Marisol Valles Ramirez ◽  
Mariana Agostini de Moraes ◽  
Marisa Masumi Beppu
Keyword(s):  
Physicochemical Properties ◽  
Silk Fibroin ◽  
Image Position

Abstract

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