Rapid and simple detection of sodium thiocyanate in milk using surface-enhanced Raman spectroscopy based on silver aggregates

2014 ◽  
Vol 45 (2) ◽  
pp. 162-167 ◽  
Author(s):  
Xiang Lin ◽  
Wu-Li-Ji Hasi ◽  
Xiu-Tao Lou ◽  
Shuang Lin ◽  
Fang Yang ◽  
...  
2015 ◽  
Vol 7 (19) ◽  
pp. 8241-8247 ◽  
Author(s):  
Mei-Ling Zhang ◽  
Wu-Li-Ji Hasi ◽  
Xiang Lin ◽  
Xiao-Rong Zhao ◽  
Xiu-Tao Lou ◽  
...  

A rapid and simple SERS method for detecting pethidine hydrochloride injection utilizing silver aggregates as the active substrate was developed.


2017 ◽  
Author(s):  
Caitlin S. DeJong ◽  
David I. Wang ◽  
Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.


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