Automated Drug Dissolution Monitor That Uses a UV-Visible Diode Array Spectrophotometer

1993 ◽  
Vol 82 (4) ◽  
pp. 350-354 ◽  
Author(s):  
Su-Chin Lo ◽  
Steven M. Donahue ◽  
Chris W. Brown
1991 ◽  
Vol 13 (3) ◽  
pp. 83-92
Author(s):  
Paul M. Shiundu ◽  
Adrian P. Wade

The UV-visible diode array spectrophotometer is a work-horse instrument for many laboratories. This article provides simple data acquisition and control routines in Microsoft QuickBasic for a HP-8452A diode array spectrophotometer interfaced to an IBM PC/XT/AT, or compatible, microcomputer. These allow capture of full spectra and measure absorbance at one or several wavelengths at preset time intervals. The variance in absorbance at each wavelength is available as an option.


1996 ◽  
Vol 50 (5) ◽  
pp. 576-582 ◽  
Author(s):  
Marcelo Blanco ◽  
Jordi Coello ◽  
Hortensia Iturriaga ◽  
Santiago Maspoch ◽  
Smail Alaoui-Ismaili

It is demonstrated that noise in UV spectral recordings obtained by using a diode array UV-visible spectrophotometer on different days may conform to a defined pattern. Such structured noise leads to the acceptance, as significant, of components containing noise alone, in calibrations by principal component regression (PCR)—which impedes the detection of outliers at the unknown sample prediction stage and considerably diminishes the potential of this methodology for control analyses. As shown in this paper, the effect of the noise structure can be substantially decreased by recording the spectra for the calibration samples on different days. Also, a procedure for distinguishing between correct samples and outliers is proposed. The procedure fits the distribution of the squared residuals of the absorbances for the calibration samples to an exponential function and uses a 99.9% probability as the acceptable limit. It was applied to analysis of ketoprofen and methylparaben mixtures.


1990 ◽  
Vol 234 ◽  
pp. 395-401 ◽  
Author(s):  
M. Blanco ◽  
J. Coello ◽  
H. Iturriaga ◽  
S. Maspoch ◽  
J. Riba

2016 ◽  
Vol 70 (5) ◽  
pp. 874-878 ◽  
Author(s):  
David Stephenson

2008 ◽  
Vol 85 (12) ◽  
pp. 1663
Author(s):  
B. T. Arneson ◽  
K. K. Stewart ◽  
J. J. Lagowski ◽  
S. R. Long

1985 ◽  
Vol 39 (4) ◽  
pp. 693-697 ◽  
Author(s):  
Henry Aryamanya-Mugisha ◽  
Ronald R. Williams

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