Determination of Iodide in Metabolic Studies of 125I-Labeled Compounds

1979 ◽  
Vol 68 (2) ◽  
pp. 258-259 ◽  
Author(s):  
Y.Y. Shum ◽  
J.E. Sinsheimer
Keyword(s):  
Labeled Compounds ◽  
Metabolic Studies

Diagnostic Application of Metabolic Studies with Isotopes

1970 ◽  
Vol 16 (8) ◽  
pp. 633-636
Author(s):  
Ferenc Hutterer ◽  
Laszlo Sarkozi ◽  
John Roboz ◽  
Paolo Bacchin
Keyword(s):  
Blood Glucose ◽  
Metabolic Pathways ◽  
Diagnostic Information ◽  
Diagnostic Application ◽  
Metabolic Studies ◽  
End Products ◽  
Disease Stages

Abstract The mechanism of the maintenance of normoglycemia in chloroform intoxication in rats was studied with isotopes. Metabolic pathways were altered before the concentration of blood glucose changed significantly. Measurement of the incorporation of precursors rather than the determination of the concentration of the metabolic end products (e.g., glucose) may provide more diagnostic information and may more sensitively detect early diseases or disease stages.

Direct determination of N-methyl-2-pyrrolidone metabolites in urine by HPLC-electrospray ionization-MS/MS using deuterium-labeled compounds as internal standard

2009 ◽  
Vol 877 (29) ◽  
pp. 3743-3747 ◽  
Author(s):  
Yoshihiro Suzuki ◽  
Yoko Endo ◽  
Masanori Ogawa ◽  
Shinobu Yamamoto ◽  
Akito Takeuchi ◽  
...  
Keyword(s):  
Electrospray Ionization ◽  
Internal Standard ◽  
Direct Determination ◽  
Labeled Compounds

THE DEGRADATION OF 2-KETO-D-GLUCONATE-C14, D-GLUCONATE-C14, AND D-FRUCTOSE-C14 BY LEUCONOSTOC MESENTEROIDES

1957 ◽  
Vol 3 (5) ◽  
pp. 741-744 ◽  
Author(s):  
E. R. Blakley ◽  
A. C. Blackwood
Keyword(s):  
Carbon Dioxide ◽  
Lactic Acid ◽  
Leuconostoc Mesenteroides ◽  
Labeled Compounds ◽  
Radioactive Carbon

2-Ketogluconate, gluconate, and fructose specifically labeled with C14 were fermented by Leuconostoc mesenteroides. Radioactive carbon dioxide was recovered from the fermentation of the C-1 labeled substrates, while methyl labeled lactic acid was recovered from the C-6 labeled compounds. The results indicate that the metabolism of these compounds and that previously reported for glucose are similar. This organism can be used to degrade these compounds for the determination of C14 distribution.

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