Metabolic Studies of the Nonnutritive Sweeteners Cyclopentylmethylsulfamate and Cyclopentylsulfamate: Determination of Metabolites in Rat Urine

1978 ◽  
Vol 67 (2) ◽  
pp. 226-228 ◽  
Author(s):  
William J. Spillane ◽  
G. Anthony Benson
Keyword(s):  
Rat Urine ◽  
Metabolic Studies

Simultaneous determination of arctiin and its metabolites in rat urine and feces by HPLC

Fitoterapia ◽  
2013 ◽  
Vol 86 ◽  
pp. 6-12 ◽  
Author(s):  
Wei Wang ◽  
Qiang Pan ◽  
Xue-Ying Han ◽  
Jing Wang ◽  
Ri-Qiu Tan ◽  
...  
Keyword(s):  
Simultaneous Determination ◽  
Rat Urine

scholarly journals Identification of Allantoin, Uric Acid, and Indoxyl Sulfate as Biochemical Indicators of Filth in Food Packaging by LC

2001 ◽  
Vol 84 (3) ◽  
pp. 782-788 ◽  
Author(s):  
Marvin Carlson ◽  
Richard D Thompson
Keyword(s):  
Uric Acid ◽  
Food Packaging ◽  
Reversed Phase ◽  
Indoxyl Sulfate ◽  
Rat Urine ◽  
Relative Standard ◽  
Analyte Content ◽  
Corrugated Cardboard ◽  
Liquid Chromatographic

Abstract A liquid chromatographic (LC) method was developed for the determination of allantoin, uric acid, and indoxyl sulfate in mammalian urine contaminated packaging material including paper bagging, corrugated cardboard, grayboard, and burlap bagging. The procedure involves solvent extraction and isolation of the 3 analytes by reversed-phase LC with ultraviolet detection at 225 nm for allantoin and 286 nm for uric acid and indoxyl sulfate. The composition of authentic mammalian urine such as mouse, rat, cat, dog, and human were also determined with regard to the 3 compounds of interest. A linear concentration range of 0.11–20.4, 0.02–10.0, and 0.04–30.0 μg/mL was obtained for allantoin, uric acid, and indoxyl sulfate, respectively. Limits of detection (LOD) and quantitation (LOQ) were 0.0104 and 0.0345 μg/mL for allantoin; 0.0018 and 0.0060 μg/mL for uric acid; and 0.0049 and 0.0165 μg/mL for indoxyl sulfate, respectively. Interday relative standard deviation values for a mixture of standard allantoin, uric acid, and indoxyl sulfate (n = 5) were 0.97, 0.80, and 0.94%, respectively. Analyte composition for 5 types of authentic mammalian urine varied from 0.19–6.88 mg/mL allantoin; 0.08–0.57 mg/mL uric acid; and 0.03–0.78 mg/mL indoxyl sulfate. Analyte content for 8 samples including 2 samples each for paper, cardboard, grayboard, and burlap bagging each contaminated with mouse or rat urine ranged from <LOD to 4598 μg/gm allantoin; <LOD to 202 μg/gm uric acid; and 17.5 to 616 μg/gm indoxyl sulfate. Recoveries of allantoin, uric acid, and indoxyl sulfate from 11 fortified samples (4 types) for both mouse and rat urine ranged from 28.2 to 114.1% for allantoin; 32.6 to 123.4% for uric acid; and 52.6 to 118.2% for indoxyl sulfate.

Identification and determination of four metabolites of mangiferin in rat urine

2007 ◽  
Vol 45 (5) ◽  
pp. 793-798 ◽  
Author(s):  
Hui Wang ◽  
Guan Ye ◽  
Chun-Hui Ma ◽  
Yi-Hong Tang ◽  
Ming-Song Fan ◽  
...  
Keyword(s):  
Rat Urine

Determination of primary amines in rat urine and plasma.

1985 ◽  
Vol 31 (6) ◽  
pp. 1079-1080 ◽  
Author(s):  
V Wormser ◽  
G Zbinden
Keyword(s):  
Primary Amines ◽  
Rat Urine
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