Cycloalkanones V: Synthesis, Distribution, and Effects on Triglyceride Metabolism

1975 ◽  
Vol 64 (2) ◽  
pp. 235-240 ◽  
Author(s):  
Iris H. Hall ◽  
Robert G. Lamb ◽  
Mei-Heng H. Mar ◽  
Gerald L. Carlson ◽  
Claude Piantadosi
Keyword(s):  
Triglyceride Metabolism

scholarly journals Triglyceride metabolism in 3T3-L1 cells. An in vivo 13C NMR study.

1992 ◽  
Vol 267 (16) ◽  
pp. 11168-11175
Author(s):  
M.R. Soma ◽  
M.P. Mims ◽  
M.V. Chari ◽  
D Rees ◽  
J.D. Morrisett
Keyword(s):  
13C Nmr ◽  
Triglyceride Metabolism ◽  
Nmr Study

Triglyceride Metabolism in the Neonate

NeoReviews ◽  
2009 ◽  
Vol 10 (12) ◽  
pp. e608-e612
Author(s):  
M. Marron-Corwin ◽  
E. Hailu
Keyword(s):  
Triglyceride Metabolism

Targeting triglyceride metabolism for colorectal cancer prevention and therapy

2021 ◽  
Vol 22 ◽  
Author(s):  
Nagendra Yarla ◽  
Venkateshwar Madka ◽  
Chinthalapally Rao
Keyword(s):  
Colorectal Cancer ◽  
Metabolic Pathways ◽  
Literature Search ◽  
Fatty Acid Synthase ◽  
The Cancer Genome Atlas ◽  
Great Promise ◽  
Triglyceride Metabolism ◽  
Proteomic Data ◽  
Colorectal Cancer Prevention ◽  
Coa Reductase

Background: Triglycerides (TG) are one of the major constituents of body fat and energy reservoir, which consist of an ester derived from glycerol and three free fatty acids. TG lipase, monoacylglycerol lipase, fatty acid synthase, and HMG-CoA reductase are some of the key enzymes related to TG metabolism, and their roles in colorectal cancer (CRC) initiation and progression are under investigation. Methods: The literature search was performed based on various published papers, mostly on triglyceride metabolism relevant to CRC in PubMed, Google Scholar and other search engines. The gene expression profiling of some of the TG metabolic pathway mediators was performed by transcriptomic and/or proteomic data from The Cancer Genome Atlas (TCGA) database using R program and cBioportal software. Results and discussion: Accumulating pieces of evidence suggest that TG profiling may be used as a biomarker for the diagnosis and/or prognosis of CRC. Dysregulation of TG metabolism is associated with the initiation and progression of CRC. Most of the TG anabolic pathway mediators are overexpressed and/or overactivated during CRC tumorigenesis, while most TG catabolic pathway mediators are downregulated and/or inactivated based on literature search and correlated with TCGA data. Metabolic enzymes of TG and FAs metabolic pathways are involved in CRC tumor growth survival and metastasis. Conclusion: Overall studies from the previous literature and our TCGA data analysis demonstrated that the area of research on TG-associated lipid metabolic pathways holds great promise and warranted detailed investigations in this area for the implementation of novel preventive and therapeutic strategies against CRC.

scholarly journals A Sucrose-Rich Diet Affects Triglyceride Metabolism Differently in Pregnant and Nonpregnant Rats and Has Negative Effects on Fetal Growth

1996 ◽  
Vol 126 (10) ◽  
pp. 2481-2486 ◽  
Author(s):  
Ana Soria ◽  
Adriana Chicco ◽  
Norberto Mocchiutti ◽  
Raul A. Gutman ◽  
Yolanda B. Lombardo ◽  
...  
Keyword(s):  
Fetal Growth ◽  
Negative Effects ◽  
Triglyceride Metabolism

393 TRIGLYCERIDE METABOLISM AND INTERLEUKIN-6 LEVELS ARE ALTERED IN CARRIERS OF THE MINOR ALLELE OF AN INTERLEUKIN-1B GENE VARIATION (-1473G/C)

2011 ◽  
Vol 12 (1) ◽  
pp. 84
Author(s):  
J. Delgado-Lista ◽  
P. Perez-Martinez ◽  
A. Garcia-Rios ◽  
J. Solivera ◽  
E.M. Yubero-Serrano ◽  
...  
Keyword(s):  
Interleukin 6 ◽  
Minor Allele ◽  
Triglyceride Metabolism ◽  
Gene Variation

scholarly journals Effect of Dibutyltin Dilaurate on Triglyceride Metabolism through the Inhibition of the mTOR Pathway in Human HL7702 Liver Cells

Molecules ◽  
2018 ◽  
Vol 23 (7) ◽  
pp. 1654 ◽  
Author(s):  
Xiaozhi Qiao ◽  
Yunlan Li ◽  
Jiaqi Mai ◽  
Xiaoqing Ji ◽  
Qingshan Li
Keyword(s):  
Liver Cells ◽  
Mtor Pathway ◽  
Dibutyltin Dilaurate ◽  
Triglyceride Metabolism
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