Irreversible enzyme inhibitors 99 Inhibitors of thymidine phosphorylase 7. Further studies on hydrophobic bonding with hydrocarbon substituents on acidic uracils

B.R. Baker; Mitsutaka Kawazu; J.D. McClure

doi:10.1002/jps.2600560906

Irreversible enzyme inhibitors 99 Inhibitors of thymidine phosphorylase 7. Further studies on hydrophobic bonding with hydrocarbon substituents on acidic uracils

Journal of Pharmaceutical Sciences ◽

10.1002/jps.2600560906 ◽

1967 ◽

Vol 56 (9) ◽

pp. 1081-1086 ◽

Cited By ~ 6

Author(s):

B.R. Baker ◽

Mitsutaka Kawazu ◽

J.D. McClure

Keyword(s):

Thymidine Phosphorylase ◽

Enzyme Inhibitors ◽

Hydrophobic Bonding

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Irreversible Enzyme Inhibitors. CIV. Inhibitors of Thymidine Phosphorylase. VIII. Further Studies on Hydrophobic Bonding with 6-Substituted Uracils

Journal of Medicinal Chemistry ◽

10.1021/jm00318a028 ◽

1967 ◽

Vol 10 (6) ◽

pp. 1109-1113 ◽

Cited By ~ 12

Author(s):

B. R. Baker ◽

Waclaw. Rzeszotarski

Keyword(s):

Thymidine Phosphorylase ◽

Enzyme Inhibitors ◽

Substituted Uracils ◽

Hydrophobic Bonding

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Irreversible enzyme inhibitors. CXXI. Thymidine phosphorylase. 9. Nature and dimensions of the hydrophobic bonding region

Journal of Medicinal Chemistry ◽

10.1021/jm00310a001 ◽

1968 ◽

Vol 11 (4) ◽

pp. 639-644 ◽

Cited By ~ 15

Author(s):

B. R. Baker ◽

Waclaw Rzeszotarski

Keyword(s):

Thymidine Phosphorylase ◽

Enzyme Inhibitors ◽

Hydrophobic Bonding

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Irreversible enzyme inhibitors. CLXVII. Thymidine phosphorylase. 10. On the nature and dimensions of the hydrophobic bonding region. A

Journal of Medicinal Chemistry ◽

10.1021/jm00295a022 ◽

1970 ◽

Vol 13 (1) ◽

pp. 87-89 ◽

Cited By ~ 13

Author(s):

Bernard Randall Baker ◽

Stephen E. Hopkins

Keyword(s):

Thymidine Phosphorylase ◽

Enzyme Inhibitors ◽

Hydrophobic Bonding

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Irreversible enzyme inhibitors. CXXX. Cytosine nucleoside deaminase. 1. Hydrophobic bonding with monosubstituted uracils

Journal of Medicinal Chemistry ◽

10.1021/jm00310a010 ◽

1968 ◽

Vol 11 (4) ◽

pp. 682-686 ◽

Cited By ~ 8

Author(s):

Bernard R. Baker ◽

James L. Kelley

Keyword(s):

Enzyme Inhibitors ◽

Hydrophobic Bonding

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Irreversible enzyme inhibitors LXXXVII. Hydrophobic bonding to dihydrofolic reductase IX. Mode of binding of m-aryloxyalkyl groups on 4, 6-diamino-1,2-dihydro-2, 2-dimethyl-1-phenyl-s-triazine

Journal of Pharmaceutical Sciences ◽

10.1002/jps.2600560717 ◽

1967 ◽

Vol 56 (7) ◽

pp. 871-875 ◽

Cited By ~ 3

Author(s):

B.R. Baker ◽

Gerhardus J. Lourens

Keyword(s):

Enzyme Inhibitors ◽

Hydrophobic Bonding

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Irreversible enzyme inhibitors. CXXXI. Cytosine nucleoside deaminase. 2. Hydrophobic bonding with disubstituted uracils and cytosines

Journal of Medicinal Chemistry ◽

10.1021/jm00310a011 ◽

1968 ◽

Vol 11 (4) ◽

pp. 686-690 ◽

Cited By ~ 12

Author(s):

B. R. Baker ◽

James L. Kelley

Keyword(s):

Enzyme Inhibitors ◽

Hydrophobic Bonding

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Irreversible enzyme inhibitors 100 Inhibitors of thymidine phosphorylase 8. 6-(p-bromoacetamido-benzyl)uracil, an active-site-directed irreversible inhibitor

Journal of Pharmaceutical Sciences ◽

10.1002/jps.2600560907 ◽

1967 ◽

Vol 56 (9) ◽

pp. 1086-1092 ◽

Cited By ~ 4

Author(s):

B.R. Baker ◽

Mitsutaka Kawazu

Keyword(s):

Active Site ◽

Thymidine Phosphorylase ◽

Enzyme Inhibitors ◽

Irreversible Inhibitor

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Irreversible enzyme inhibitors. CXXII. Nature and dimensions of the hydrophobic bonding region of guanine deaminase and xanthine oxidase

Journal of Medicinal Chemistry ◽

10.1021/jm00310a002 ◽

1968 ◽

Vol 11 (4) ◽

pp. 644-649 ◽

Cited By ~ 14

Author(s):

B. R. Baker ◽

William F. Wood

Keyword(s):

Xanthine Oxidase ◽

Enzyme Inhibitors ◽

Guanine Deaminase ◽

Hydrophobic Bonding

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Irreversible Enzyme Inhibitors. LXXVII.1,2Inhibitors of Thymidine Phosphorylase. III.2Hydrophobic Bonding by 1-Substituted Uracils Containing Additional Substituents at the 5 and 6 Positions

Journal of Medicinal Chemistry ◽

10.1021/jm00315a003 ◽

1967 ◽

Vol 10 (3) ◽

pp. 304-311 ◽

Cited By ~ 20

Author(s):

B. R. Baker ◽

Mitsutaka. Kawazu ◽

Daniel V. Santi ◽

Thomas J. Schwan

Keyword(s):

Thymidine Phosphorylase ◽

Enzyme Inhibitors ◽

Substituted Uracils

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Irreversible enzyme inhibitors. CLXII. Hydrophobic bonding to cytosine nucleoside deaminase with 1-substituted 5-arylcytosines

Journal of Medicinal Chemistry ◽

10.1021/jm00306a017 ◽

1969 ◽

Vol 12 (6) ◽

pp. 1039-1045 ◽

Cited By ~ 3

Author(s):

Bernard Randall Baker ◽

James L. Kelley

Keyword(s):

Enzyme Inhibitors ◽

Hydrophobic Bonding

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