Preparation of Caffeic Acid Phenethyl Ester-Incorporated Nanoparticles and Their Biological Activity

2015 ◽  
Vol 104 (1) ◽  
pp. 144-154 ◽  
Author(s):  
Hyo-Young Lee ◽  
Young-Il Jeong ◽  
Eun Jin Kim ◽  
Kyung Dong Lee ◽  
Seon-Hee Choi ◽  
...  
2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Martin J. G. Hébert ◽  
Andrew J. Flewelling ◽  
Trevor N. Clark ◽  
Natalie A. Levesque ◽  
Jacques Jean-François ◽  
...  

Two novel boron compounds containing caffeic acid phenethyl ester (CAPE) derivatives have been prepared and characterized fully. These new compounds and CAPE have been investigated for potential antioxidant and antimicrobial properties and their ability to inhibit 5-lipoxygenase and whether chelation to boron improves their biological activity. Sodium salt 4 was generally more active than ammonium salt 5 in the biological assays and surpassed the radical scavenging ability of CAPE. Compounds 4 and 5 were more active than CAPE and Zileuton in human polymorphonuclear leukocytes. These results clearly show the effectiveness of the synthesized salts as transporter of CAPE.


Author(s):  
Valeria Pittala ◽  
Luca Vanella ◽  
Loredana Salerno ◽  
Claudia Di Giacomo ◽  
Rosaria Acquaviva ◽  
...  

2021 ◽  
Vol 64 (1) ◽  
Author(s):  
Aslı Özkök ◽  
Merve Keskin ◽  
Aslı Elif Tanuğur Samancı ◽  
Elif Yorulmaz Önder ◽  
Çiğdem Takma

AbstractThis study aimed to determine the standard amount of antioxidant content and compounds of the propolis for the standardization of propolis. For this purpose, the total flavonoids, total phenolic, CUPRAC antioxidant capacity content and the diversity of phenolic and flavonoid components of these propolis samples were found by HPLC determined at the 23 propolis samples which were collected different regions of Turkey. Beside that, the similarities and differences of these 23 provinces to each other according to their antioxidant capacities were investigated by multidimensional scaling analysis. The total flavonoid content in the propolis samples were determined between 21.28 and 152.56 mg CE/g. The total phenolic content in the propolis samples was found between 34.53 mg and 259.4 mg GAE/g. CUPRAC antioxidant capacity of the propolis samples and antioxidant range was found from 95.35 to 710.43 mg TE/g. Also, 4 flavonoid [Quercetin (min.1.12–max.4.14 mg/g), Galangin (min.0.72–max.40.79 mg/g), Apigenin (min.1.07–max.17.35 mg/g), Pinocembrin (min.1.32–max.39.92 mg/g] and 6 phenolic acid [Caffeic acid (min.1.20–max.7.6 mg/g), p-Coumaric acid (min.1.26–max.4.47 mg/g), trans-Ferulic acid (min.1.28–max.4.92 mg/g), Protocatechuic acid (1.78 mg/g), trans-Cinnamic acid (min.1.05–max.3.83 mg/g), Caffeic Acid Phenethyl Ester (CAPE) (min.1.41–max.30.15 mg/g)] components were detected as mg/g, in different ratios in propolis samples collected from different regions. The feature of this study, so far, is to have the maximum number of samples representing the Turkish propolis, and so is thought to help to national and international propolis standard workings.


Life Sciences ◽  
2008 ◽  
Vol 82 (13-14) ◽  
pp. 797-805 ◽  
Author(s):  
Won-Kyo Jung ◽  
Da-Young Lee ◽  
Yung Hyun Choi ◽  
Sung Su Yea ◽  
Inhak Choi ◽  
...  

2017 ◽  
Vol 95 ◽  
pp. 127-132 ◽  
Author(s):  
İbrahim Ağrı ◽  
Arzu Erdal Ağrı ◽  
Mehmet Eser Sancaktar ◽  
Asude Ünal ◽  
Erkan Can ◽  
...  

1988 ◽  
Vol 44 (3) ◽  
pp. 230-232 ◽  
Author(s):  
D. Grunberger ◽  
R. Banerjee ◽  
K. Eisinger ◽  
E. M. Oltz ◽  
L. Efros ◽  
...  

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