Effect of Water on the Chemical Stability of Amorphous Pharmaceuticals: I. Small Molecules

2013 ◽  
Vol 102 (4) ◽  
pp. 1139-1154 ◽  
Author(s):  
Satoshi Ohtake ◽  
Evgenyi Shalaev
Keyword(s):  
Small Molecules ◽  
Chemical Stability ◽  
Amorphous Pharmaceuticals ◽  
Effect Of Water

scholarly journals Light-induced crosslinkable semiconducting polymer dots

2015 ◽  
Vol 6 (3) ◽  
pp. 2102-2109 ◽  
Author(s):  
Yue Zhang ◽  
Fangmao Ye ◽  
Wei Sun ◽  
Jiangbo Yu ◽  
I-Che Wu ◽  
...  
Keyword(s):  
Small Molecules ◽  
Chemical Stability ◽  
Semiconducting Polymer ◽  
Polymer Dots ◽  
Semiconducting Polymer Dots ◽  
Physical And Chemical

This paper describes photocrosslinkable Pdots with enhanced colloidal, physical, and chemical stability, and excellent encapsulating ability of functional small molecules.

scholarly journals Freezing of Aqueous Solutions and Chemical Stability of Amorphous Pharmaceuticals: Water Clusters Hypothesis

2019 ◽  
Vol 108 (1) ◽  
pp. 36-49 ◽  
Author(s):  
Evgenyi Shalaev ◽  
Alan Soper ◽  
J. Axel Zeitler ◽  
Satoshi Ohtake ◽  
Christopher J. Roberts ◽  
...  
Keyword(s):  
Aqueous Solutions ◽  
Chemical Stability ◽  
Water Clusters ◽  
Amorphous Pharmaceuticals

Chemical stability of peptides in polymers. 1. Effect of water on peptide deamidation in poly(vinyl alcohol) and poly(vinyl pyrrolidone) matrixes

1999 ◽  
Vol 88 (10) ◽  
pp. 1073-1080 ◽  
Author(s):  
Mei C. Lai ◽  
Michael J. Hageman ◽  
Richard L. Schowen ◽  
Ronald T. Borchardt ◽  
Elizabeth M. Topp
Keyword(s):  
Chemical Stability ◽  
Vinyl Alcohol ◽  
Vinyl Pyrrolidone ◽  
Poly Vinyl Alcohol ◽  
Effect Of Water ◽  
Poly Vinyl Pyrrolidone

scholarly journals Effect of Water on Molecular Mobility and Physical Stability of Amorphous Pharmaceuticals

2016 ◽  
Vol 13 (4) ◽  
pp. 1339-1346 ◽  
Author(s):  
Mehak Mehta ◽  
Khushboo Kothari ◽  
Vishard Ragoonanan ◽  
Raj Suryanarayanan
Keyword(s):  
Molecular Mobility ◽  
Physical Stability ◽  
Amorphous Pharmaceuticals ◽  
Effect Of Water

Diffusion of small molecules in edible films: Effect of water and interactions between diffusant and biopolymer

2008 ◽  
Vol 106 (4) ◽  
pp. 1340-1349 ◽  
Author(s):  
Thomas Karbowiak ◽  
Régis D. Gougeon ◽  
Séverinne Rigolet ◽  
Luc Delmotte ◽  
Frédéric Debeaufort ◽  
...  
Keyword(s):  
Small Molecules ◽  
Edible Films ◽  
Effect Of Water

Gap junctions in the prothoracic glands of the tobacco hornworm, Manduca sexta

1992 ◽  
Vol 50 (1) ◽  
pp. 706-707
Author(s):  
Ji-da Dai ◽  
M. Joseph Costello ◽  
Lawrence I. Gilbert
Keyword(s):  
Gap Junctions ◽  
Small Molecules ◽  
Manduca Sexta ◽  
Freeze Fracture ◽  
Cell Communication ◽  
Cellular Level ◽  
Thin Sections ◽  
Prothoracic Glands ◽  
Polyhydroxylated Steroids ◽  
Stimulation Of

Insect molting and metamorphosis are elicited by a class of polyhydroxylated steroids, ecdysteroids, that originate in the prothoracic glands (PGs). Prothoracicotropic hormone stimulation of steroidogenesis by the PGs at the cellular level involves both calcium and cAMP. Cell-to-cell communication mediated by gap junctions may play a key role in regulating signal transduction by controlling the transmission of small molecules and ions between adjacent cells. This is the first report of gap junctions in the PGs, the evidence obtained by means of SEM, thin sections and freeze-fracture replicas.

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