High-Throughput Melting-Temperature Analysis of a Monoclonal Antibody by Differential Scanning Fluorimetry in the Presence of Surfactants

2013 ◽  
Vol 102 (2) ◽  
pp. 415-428 ◽  
Author(s):  
Tim Menzen ◽  
Wolfgang Friess
Keyword(s):  
Monoclonal Antibody ◽  
Melting Temperature ◽  
High Throughput ◽  
Temperature Analysis ◽  
Differential Scanning Fluorimetry

A high throughput β-globin genotyping method by multiplexed melting temperature analysis

2004 ◽  
Vol 81 (3) ◽  
pp. 237-243 ◽  
Author(s):  
Zhili Lin ◽  
Joseph G Suzow ◽  
Jamie M Fontaine ◽  
Edwin W Naylor
Keyword(s):  
Melting Temperature ◽  
High Throughput ◽  
Temperature Analysis ◽  
Genotyping Method

scholarly journals Selective protein unfolding: a universal mechanism of action for the development of irreversible inhibitors

2018 ◽  
Vol 54 (14) ◽  
pp. 1738-1741 ◽  
Author(s):  
Samuel Askin ◽  
Thomas E. H. Bond ◽  
Alanna E. Sorenson ◽  
Morgane J. J. Moreau ◽  
Helma Antony ◽  
...  
Keyword(s):  
High Throughput ◽  
Mechanism Of Action ◽  
Protein Unfolding ◽  
Enzyme Inhibitors ◽  
Irreversible Inhibitors ◽  
Differential Scanning Fluorimetry ◽  
Universal Mechanism

Selective protein unfolding was combined with high-throughput differential scanning fluorimetry of GFP-tagged proteins for the identification of irreversible enzyme inhibitors.

scholarly journals Impact of media and antifoam selection on monoclonal antibody production and quality using a high throughput micro-bioreactor system

2017 ◽  
Vol 34 (1) ◽  
pp. 262-270 ◽  
Author(s):  
Sai Rashmika Velugula-Yellela ◽  
Abasha Williams ◽  
Nicholas Trunfio ◽  
Chih-Jung Hsu ◽  
Brittany Chavez ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
High Throughput ◽  
Antibody Production ◽  
Monoclonal Antibody Production ◽  
Bioreactor System

High-throughput determination of free d-aspartic acid in mammals by enzyme immunoassay using specific monoclonal antibody

2006 ◽  
Vol 357 (1) ◽  
pp. 15-20 ◽  
Author(s):  
Tomohiro Ohgusu ◽  
Kenji Hamase ◽  
Hiroyuki Tanaka ◽  
Yukihiro Shoyama ◽  
Kiyoshi Zaitsu
Keyword(s):  
Monoclonal Antibody ◽  
Enzyme Immunoassay ◽  
Aspartic Acid ◽  
High Throughput ◽  
Specific Monoclonal Antibody

A predictive high-throughput scale-down model of monoclonal antibody production in CHO cells

2009 ◽  
Vol 104 (6) ◽  
pp. 1107-1120 ◽  
Author(s):  
Rachel Legmann ◽  
H. Brett Schreyer ◽  
Rodney G. Combs ◽  
Ellen L. McCormick ◽  
A. Peter Russo ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
High Throughput ◽  
Antibody Production ◽  
Cho Cells ◽  
Monoclonal Antibody Production ◽  
Scale Down

Melting Temperature Analysis as Quantitative Method for Detection of Point Mutations

2001 ◽  
Vol 39 (6) ◽  
Author(s):  
Brunetta Porcelli ◽  
Barbara Frosi ◽  
Lucia Terzuoli ◽  
Laura Arezzini ◽  
Roberto Pagani ◽  
...  
Keyword(s):  
Melting Temperature ◽  
Quantitative Method ◽  
Point Mutations ◽  
Temperature Analysis

High throughput chromatography strategies for potential use in the formal process characterization of a monoclonal antibody

2015 ◽  
Vol 113 (6) ◽  
pp. 1273-1283 ◽  
Author(s):  
Matthew G. Petroff ◽  
Haiying Bao ◽  
John P. Welsh ◽  
Miranda van Beuningen - de Vaan ◽  
Jennifer M. Pollard ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
High Throughput ◽  
Formal Process ◽  
Process Characterization ◽  
Potential Use

Haplotyping of TNFalpha gene promoter using melting temperature analysis: detection of a novel -856(G/A) mutation

2005 ◽  
Vol 66 (4) ◽  
pp. 284-290 ◽  
Author(s):  
Y. Song ◽  
J. Araki ◽  
L. Zhang ◽  
T. Froehlich ◽  
M. Sawabe ◽  
...  
Keyword(s):  
Melting Temperature ◽  
Gene Promoter ◽  
Temperature Analysis
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