In Situ Monitoring of Proteins during Lyophilization using Micro-Raman Spectroscopy: A Description of Structural Changes induced by Dehydration

2012 ◽  
Vol 101 (7) ◽  
pp. 2316-2326 ◽  
Author(s):  
Alain Hédoux ◽  
Laurent Paccou ◽  
Samira Achir ◽  
Yannick Guinet
2006 ◽  
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Ala H.R. Al-Obaidi ◽  
Soo-Keun Lee ◽  
Daniel McStay ◽  
Peter K.J. Robertson

2018 ◽  
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Elise Dropsit ◽  
Jacques Desbrières ◽  
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Sandrine Hoppe ◽  
Alain Durand ◽  
...  

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Jen-Yu Liu ◽  
Shin-Hwa Tzing ◽  
...  

2005 ◽  
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R. Ramy Ratiarison ◽  
...  

A unique combination of in situ synchrotron x-ray diffraction and in situ micro-Raman spectroscopy was used to study the growth process of YBa2Cu3O6+x films obtained by metal organic decomposition using trifluoroacetate precursor on LaAlO3 substrates. The techniques give complementary information: x-ray diffraction gives insight into the structural growth, whereas micro-Raman spectroscopy gives information of the chemical composition with additional information on the texture. To perform both experiments in situ, a special high-temperature process chamber was designed.


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