Preventing release in the acidic environment of the stomach via occlusion in ordered mesoporous silica enhances the absorption of poorly soluble weakly acidic drugs

2011 ◽  
Vol 100 (11) ◽  
pp. 4864-4876 ◽  
Author(s):  
Michiel van Speybroeck ◽  
Randy Mellaerts ◽  
Thao Do Thi ◽  
Johan A. Martens ◽  
Jan Van Humbeeck ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Acidic Environment ◽  
Ordered Mesoporous Silica ◽  
Acidic Drugs ◽  
Ordered Mesoporous ◽  
Poorly Soluble

Enhanced absorption of the poorly soluble drug fenofibrate by tuning its release rate from ordered mesoporous silica

2010 ◽  
Vol 41 (5) ◽  
pp. 623-630 ◽  
Author(s):  
Michiel Van Speybroeck ◽  
Randy Mellaerts ◽  
Raf Mols ◽  
Thao Do Thi ◽  
Johan Adriaan Martens ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Release Rate ◽  
Ordered Mesoporous Silica ◽  
Enhanced Absorption ◽  
Ordered Mesoporous ◽  
Poorly Soluble ◽  
Poorly Soluble Drug

Potential of ordered mesoporous silica for oral delivery of poorly soluble drugs

2011 ◽  
Vol 2 (8) ◽  
pp. 1079-1091 ◽  
Author(s):  
Monica Vialpando ◽  
Johan A Martens ◽  
Guy Van den Mooter
Keyword(s):  
Mesoporous Silica ◽  
Oral Delivery ◽  
Ordered Mesoporous Silica ◽  
Poorly Soluble Drugs ◽  
Ordered Mesoporous ◽  
Poorly Soluble

Evaluation of ordered mesoporous silica as a carrier for poorly soluble drugs: Influence of pressure on the structure and drug release

2011 ◽  
Vol 100 (8) ◽  
pp. 3411-3420 ◽  
Author(s):  
Monica Vialpando ◽  
Alexander Aerts ◽  
Jeroen Persoons ◽  
Johan Martens ◽  
Guy Van Den Mooter
Keyword(s):  
Drug Release ◽  
Mesoporous Silica ◽  
Ordered Mesoporous Silica ◽  
Poorly Soluble Drugs ◽  
Ordered Mesoporous ◽  
Poorly Soluble

Ordered Mesoporous Silica Material SBA-15: A Broad-Spectrum Formulation Platform for Poorly Soluble Drugs

2009 ◽  
Vol 98 (8) ◽  
pp. 2648-2658 ◽  
Author(s):  
Michiel Van Speybroeck ◽  
Valéry Barillaro ◽  
Thao Do Thi ◽  
Randy Mellaerts ◽  
Johan Martens ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Broad Spectrum ◽  
Ordered Mesoporous Silica ◽  
Poorly Soluble Drugs ◽  
Mesoporous Silica Material ◽  
Silica Material ◽  
Ordered Mesoporous ◽  
Poorly Soluble

Ordered Mesoporous Silica for the Delivery of Poorly Soluble Drugs

2011 ◽  
pp. 203-219 ◽  
Author(s):  
Michiel Van Speybroeck ◽  
Randy Mellaerts ◽  
Johan Adriaan Martens ◽  
Pieter Annaert ◽  
Guy Van den Mooter ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Ordered Mesoporous Silica ◽  
Poorly Soluble Drugs ◽  
Ordered Mesoporous ◽  
Poorly Soluble

Direct manipulation of particle size and morphology of ordered mesoporous silica by flow synthesis

RSC Advances ◽  
2015 ◽  
Vol 5 (18) ◽  
pp. 13331-13340 ◽  
Author(s):  
T. N. Ng ◽  
X. Q. Chen ◽  
K. L. Yeung
Keyword(s):  
Particle Size ◽  
Mesoporous Silica ◽  
Hollow Spheres ◽  
Ordered Mesoporous Silica ◽  
Direct Manipulation ◽  
Flow Synthesis ◽  
Precise Control ◽  
Ordered Mesoporous ◽  
Particle Size And Morphology ◽  
Size And Morphology

Flow-synthesis of mesoporous silica allows deliberate and precise control over the size and shapes and enables the preparation of complex microstructures (i.e., hollow spheres).

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