Freeze-Drying in Novel Container System: Characterization of Heat and Mass Transfer in Glass Syringes

2010 ◽  
Vol 99 (7) ◽  
pp. 3188-3204 ◽  
Author(s):  
Sajal M. Patel ◽  
Michael J. Pikal
2020 ◽  
Vol 154 ◽  
pp. 309-316
Author(s):  
Rebecca Chamberlain ◽  
Jonas Schlauersbach ◽  
Matthias Erber

2004 ◽  
Vol 5 (4) ◽  
pp. 54-62 ◽  
Author(s):  
Shailaja Rambhatla ◽  
Roee Ramot ◽  
Chandan Bhugra ◽  
Michael J. Pikal

2003 ◽  
Vol 21 (2) ◽  
pp. 249-263 ◽  
Author(s):  
Farial Jafar ◽  
Mohammed Farid

1994 ◽  
Vol 116 (1) ◽  
pp. 215-220 ◽  
Author(s):  
Shi-Wen Peng ◽  
Guo-Qian Chen

The present work discusses coupled heat and mass transfer during freeze-drying of a rigid product, as well as accelerated freeze-drying where sublimation and desorption occur concurrently. A desorption mushy zone model was developed to describe the desorption drying. An exact solution was obtained for coupled heat and mass transfer with one discrete sublimation moving interface and one desorption mushy zone where mass transfer is controlled by both Fick and Darcy laws. The effects of several parameters on the sublimation and desorption are analyzed and discussed.


2004 ◽  
Vol 59 (14) ◽  
pp. 2921-2928 ◽  
Author(s):  
Hongwei Wu ◽  
Zhi Tao ◽  
Guohua Chen ◽  
Hongwu Deng ◽  
Guoqiang Xu ◽  
...  

Author(s):  
Patrick Perre ◽  
Arnaud Challansonnex

The present work is focused on mass transfer characterization of hygroscopic materials used for insulation, such as Low Density Fibreboards. Due to their particular morphology, these panels present a very high mass diffusivity in the connected gaseous phase and a very low thermal conductivity. This combination of properties exacerbates the coupling between heat and mass transfer in transient state. Based on experimental data obtained with an original set-up and relevant simulations performed using a comprehensive physical formulation, a throughout vision of this question is proposed in the present study. In particular, we emphasize on: - The impressive change in core temperature in terms of magnitude and duration, - The great impact of the internal temperature gradient, which slows down mass diffusion, - The dramatic error on mass diffusivity value if the coupling is ignored. Keywords: experiment; identification; modelling; RH at back-face; transient state


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