Sulfoalkyl Ether-Alkyl Ether Cyclodextrin Derivatives, their Synthesis, NMR Characterization, and Binding of 6α-Methylprednisolone

2005 ◽  
Vol 94 (11) ◽  
pp. 2380-2392 ◽  
Author(s):  
Serena Tongiani ◽  
David Vander Velde ◽  
Tetsuya Ozeki ◽  
Valentino J. Stella
Keyword(s):  
Alkyl Ether ◽  
Cyclodextrin Derivatives ◽  
Nmr Characterization

Sulfobutyl ether-alkyl ether mixed cyclodextrin derivatives with enhanced inclusion ability

2009 ◽  
Vol 98 (12) ◽  
pp. 4769-4780 ◽  
Author(s):  
Serena Tongiani ◽  
Tetsuya Ozeki ◽  
Valentino J. Stella
Keyword(s):  
Alkyl Ether ◽  
Cyclodextrin Derivatives ◽  
Sulfobutyl Ether ◽  
Inclusion Ability

NMR characterization of complex natural products: Assigning novel, proton-deficient alkaloid scaffolds

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
KR Gustafson ◽  
STS Chan ◽  
D Milanowski
Keyword(s):  
Natural Products ◽  
Nmr Characterization

Camelina sativa glucosinolate fraction: NMR characterization and effect on human colon cell lines

2019 ◽  
Author(s):  
C Magoni ◽  
M Forcella ◽  
Giustra CM ◽  
D Panzeri ◽  
F Saliu ◽  
...  
Keyword(s):  
Cell Lines ◽  
Human Colon ◽  
Camelina Sativa ◽  
Nmr Characterization ◽  
Colon Cell

Synthesis and 31 P NMR characterization of new low toxic highly sensitive pH probes designed for in vivo acidic pH studies

2002 ◽  
Vol 10 (5) ◽  
pp. 1451-1458 ◽  
Author(s):  
Sophie Martel ◽  
Jean-Louis Clément ◽  
Agnès Muller ◽  
Marcel Culcasi ◽  
Sylvia Pietri
Keyword(s):  
Acidic Ph ◽  
Highly Sensitive ◽  
Nmr Characterization ◽  
Low Toxic ◽  
Ph Probes

Boron insertion into alkyl ether bonds via zinc/nickel tandem catalysis

Science ◽  
2021 ◽  
Vol 372 (6538) ◽  
pp. 175-182
Author(s):  
Hairong Lyu ◽  
Ilia Kevlishvili ◽  
Xuan Yu ◽  
Peng Liu ◽  
Guangbin Dong
Keyword(s):  
Nickel Catalyst ◽  
Bioactive Compounds ◽  
Cyclic Ethers ◽  
Alkyl Ether ◽  
Tandem Catalysis ◽  
Mechanistic Studies ◽  
Alkyl Ethers ◽  
Nitrogen Substitution ◽  
Zinc Nickel

Mild methods to cleave the carbon-oxygen (C−O) bond in alkyl ethers could simplify chemical syntheses through the elaboration of these robust, readily available precursors. Here we report that dibromoboranes react with alkyl ethers in the presence of a nickel catalyst and zinc reductant to insert boron into the C−O bond. Subsequent reactivity can effect oxygen-to-nitrogen substitution or one-carbon homologation of cyclic ethers and more broadly streamline preparation of bioactive compounds. Mechanistic studies reveal a cleavage-then-rebound pathway via zinc/nickel tandem catalysis.

Sign in / Sign up

Export Citation Format

Share Document