Polymorph screening: Influence of solvents on the rate of solvent-mediated polymorphic transformation

2001 ◽  
Vol 90 (11) ◽  
pp. 1878-1890 ◽  
Author(s):  
Chong-Hui Gu ◽  
Victor Young ◽  
David J.W. Grant
Keyword(s):  
Polymorphic Transformation ◽  
Polymorph Screening ◽  
Influence Of Solvents

scholarly journals Solvent-Mediated Polymorphic Transformation of Famoxadone from Form II to Form I in Several Mixed Solvent Systems

Crystals ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. 161 ◽  
Author(s):  
Dan Du ◽  
Guo-Bin Ren ◽  
Ming-Hui Qi ◽  
Zhong Li ◽  
Xiao-Yong Xu
Keyword(s):  
Polymorphic Transformation ◽  
Growth Process ◽  
Mixed Solvent ◽  
Transformation Process ◽  
Stable Form ◽  
Transformation Rate ◽  
Metastable Form ◽  
Dipolar Polarizability ◽  
Solvent Systems ◽  
Polymorph Screening

This paper discloses six polymorphs of famoxadone obtained from polymorph screening, which were characterized by XRPD, DSC, and SEM. A study of solvent-mediated polymorphic transformation (SMPT) of famoxadone from the metastable Form II to the stable Form I in several mixed solvent systems at the temperature of 30 °C was also conducted. The transformation process was monitored by Process Analytical Technologies. It was confirmed that the Form II to Form I polymorphic transformation is controlled by the Form I growth process. The transformation rate constants depended linearly on the solubility difference value between Form I and Form II. Furthermore, the hydrogen-bond-donation/acceptance ability and dipolar polarizability also had an effect on the rate of solvent-mediated polymorphic transformation.

Influence of Solvents on the Growth of Copper Sulfate Pentahydrate Single Crystals

2017 ◽  
Vol 13 (3) ◽  
pp. 81-94
Author(s):  
Tariq A. AL- Dhahir ◽  
◽  
Nabeel A. Bakr ◽  
Saja B. Mohammed
Keyword(s):  
Single Crystals ◽  
Copper Sulfate ◽  
Sulfate Pentahydrate ◽  
Copper Sulfate Pentahydrate ◽  
Influence Of Solvents

Influence of solvents on transmission of substituent effects by the oxygen and sulfur bridges

1974 ◽  
Vol 39 (7) ◽  
pp. 1862-1868 ◽  
Author(s):  
A. Perjéssy ◽  
G. Melikian ◽  
P. Hrnčiar ◽  
M. Lácová
Keyword(s):  
Substituent Effects ◽  
Influence Of Solvents

Influence of Solvents upon Diketopiperazine Formation of FPG8K

2021 ◽  
Author(s):  
Zhi-chao Zhang ◽  
Shannon A. Raab ◽  
David A. Hales ◽  
David E. Clemmer
Keyword(s):  
Diketopiperazine Formation ◽  
Influence Of Solvents

scholarly journals The Influence of Solvents on the Stability of Carbonated Hydroxyapatite

Proceedings ◽  
2019 ◽  
Vol 29 (1) ◽  
pp. 68
Author(s):  
Minea ◽  
Ion ◽  
Sorescu
Keyword(s):  
Cultural Heritage ◽  
Carbonated Hydroxyapatite ◽  
The Stability ◽  
Influence Of Solvents

Hydroxyapatite is an inorganic consolidant used in the restoration of cultural heritage. For thisreason, the study of the effects of different agents on hydroxyapatite is paramount [...]

Features of forming the α-phase in zirconium pseudo single crystals during their polymorphic transformation

2010 ◽  
Vol 1 (3) ◽  
pp. 238-244
Author(s):  
Yu. V. Khlebnikova ◽  
D. P. Rodionov ◽  
Yu. V. Kaletina ◽  
V. A. Sazonova ◽  
I. L. Solodova
Keyword(s):  
Single Crystals ◽  
Polymorphic Transformation ◽  
Α Phase
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