scholarly journals Definition of a Solvent System for Spherical Crystallization of Salbutamol Sulfate by Quasi‐Emulsion Solvent Diffusion (QESD) Method

2001 ◽  
Vol 90 (10) ◽  
pp. 1620-1627 ◽  
Author(s):  
M. Nocent ◽  
L. Bertocchi ◽  
F. Espitalier ◽  
M. Baron ◽  
G. Couarraze
Keyword(s):  
Solvent System ◽  
Salbutamol Sulfate ◽  
Solvent Diffusion ◽  
Spherical Crystallization ◽  
Definition Of

Continuous Spherical Crystallization of Lysozyme in an Oscillatory Baffled Crystallizer Using Emulsion Solvent Diffusion in Droplets

2020 ◽  
Vol 20 (2) ◽  
pp. 934-947 ◽  
Author(s):  
Joseph A. Oliva ◽  
Wei-Lee Wu ◽  
Michael R. Greene ◽  
Kanjakha Pal ◽  
Zoltan K. Nagy
Keyword(s):  
Solvent Diffusion ◽  
Spherical Crystallization

scholarly journals Spherical crystallization of drugs

2012 ◽  
Vol 62 (1) ◽  
pp. 1-14 ◽  
Author(s):  
Borut Kovačič ◽  
Franc Vrečer ◽  
Odon Planinšek
Keyword(s):  
Mechanical Properties ◽  
Process Parameters ◽  
Physical And Mechanical Properties ◽  
Spherical Particles ◽  
Direct Compression ◽  
Solvent Diffusion ◽  
Spherical Crystallization ◽  
Stirring Rate ◽  
Diffusion Systems ◽  
Rate Type

Spherical crystallization of drugs Spherical crystallization of drugs is the process of obtaining larger particles by agglomeration during crystallization. The most common techniques used to obtain such particles are spherical agglomeration and quasi-emulsion solvent diffusion. Ammonia diffusion systems and crystallo-co-agglomeration are extensions of these techniques. By controlling process parameters during crystallization, such as temperature, stirring rate, type and amount of solvents, or excipient selection, it is possible to control the formation of agglomerates and obtain spherical particles of the desired size, porosity, or hardness. Researchers have reported that the particles produced have improved micromeritic, physical, and mechanical properties, which make them suitable for direct compression. In some cases, when additional excipients are incorporated during spherical crystallization, biopharmaceutical parameters including the bioavailability of drugs can also be tailored.

Reduction of Punch-Sticking Propensity of Celecoxib by Spherical Crystallization via Polymer Assisted Quasi-Emulsion Solvent Diffusion

2020 ◽  
Vol 17 (4) ◽  
pp. 1387-1396 ◽  
Author(s):  
Hongbo Chen ◽  
Shubhajit Paul ◽  
Hongyun Xu ◽  
Kunlin Wang ◽  
Mahesh K. Mahanthappa ◽  
...  
Keyword(s):  
Solvent Diffusion ◽  
Spherical Crystallization

scholarly journals Spherical Crystallization: Modeling of the Emulsion Solvent Diffusion Technique

1997 ◽  
Vol 15 (0) ◽  
pp. 159-169
Author(s):  
Fabienne Espitalier ◽  
Béatrice Biscans ◽  
Claude Laguerie ◽  
Michel Deleuil
Keyword(s):  
Solvent Diffusion ◽  
Spherical Crystallization ◽  
Diffusion Technique

Hydroosmotic pressure

2019 ◽  
Vol 484 (1) ◽  
pp. 52-55
Author(s):  
N. M. Bazhin ◽  
V. N. Parmon
Keyword(s):  
Hydrostatic Pressure ◽  
Osmotic Pressure ◽  
Dissolved Solids ◽  
Solvent Diffusion ◽  
Correct Definition ◽  
The Difference ◽  
Definition Of

This work proposes the term “hydroosmotic pressure” to define hydrostatic pressure emerging from an osmotic process during solvent diffusion through membranes. The usage of this term potentially clears the ambiguity of the term “osmotic pressure,” referring to the concentration of dissolved solids in a solution regardless of the existence of hydrostatic pressure. Hydroosmotic pressure is the difference between hydrostatic pressures on either side of the membrane; thus, the term “hydroosmotic pressure” allows for the most correct definition of many processes associated with osmotic phenomena.

Sign in / Sign up

Export Citation Format

Share Document