ROBING THE ROLE OF METHYL METHACRYLATE RELEASE FROM SPACER MATERIALS IN INDUCED MEMBRANE BONE HEALING

2021 ◽  
Author(s):  
A. Stahl ◽  
YB. Park ◽  
SH. Park ◽  
S. Lin ◽  
C.C. Pan ◽  
...  
Keyword(s):  
Methyl Methacrylate ◽  
Bone Healing ◽  
Induced Membrane ◽  
Membrane Bone

The role of IFT140 in early bone healing of tooth extraction sockets

Oral Diseases ◽  
2021 ◽  
Author(s):  
Shuang Zhou ◽  
Gongchen Li ◽  
Tingting Zhou ◽  
Shuai Zhang ◽  
Hui Xue ◽  
...  
Keyword(s):  
Bone Healing ◽  
Tooth Extraction

scholarly journals Direct contribution of skeletal muscle mesenchymal progenitors to bone repair

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Anais Julien ◽  
Anuya Kanagalingam ◽  
Ester Martínez-Sarrà ◽  
Jérome Megret ◽  
Marine Luka ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Bone Healing ◽  
Bone Repair ◽  
Fibrotic Response ◽  
Mesenchymal Progenitors ◽  
Fibrotic Tissue ◽  
Bone Injury ◽  
Single Cell Rna Sequencing ◽  
Musculoskeletal Trauma

AbstractBone regenerates by activation of tissue resident stem/progenitor cells, formation of a fibrous callus followed by deposition of cartilage and bone matrices. Here, we show that mesenchymal progenitors residing in skeletal muscle adjacent to bone mediate the initial fibrotic response to bone injury and also participate in cartilage and bone formation. Combined lineage and single-cell RNA sequencing analyses reveal that skeletal muscle mesenchymal progenitors adopt a fibrogenic fate before they engage in chondrogenesis after fracture. In polytrauma, where bone and skeletal muscle are injured, skeletal muscle mesenchymal progenitors exhibit altered fibrogenesis and chondrogenesis. This leads to impaired bone healing, which is due to accumulation of fibrotic tissue originating from skeletal muscle and can be corrected by the anti-fibrotic agent Imatinib. These results elucidate the central role of skeletal muscle in bone regeneration and provide evidence that skeletal muscle can be targeted to prevent persistent callus fibrosis and improve bone healing after musculoskeletal trauma.

Role of Metformin in Reversing the Negative Impact of Hyperglycemia on Bone Healing Around Implants Inserted in Type 2 Diabetic Rats

2017 ◽  
Vol 32 (3) ◽  
pp. 547-554 ◽  
Author(s):  
Caroline Serrão ◽  
Marta Bastos ◽  
Daniele Cruz ◽  
Fernando Malta ◽  
Paolla Vallim ◽  
...  
Keyword(s):  
Bone Healing ◽  
Negative Impact ◽  
Diabetic Rats ◽  
Type 2 Diabetic

The active role of Ca2+ ions in Aβ-mediated membrane damage

2018 ◽  
Vol 54 (29) ◽  
pp. 3629-3631 ◽  
Author(s):  
Michele F. M. Sciacca ◽  
Irene Monaco ◽  
Carmelo La Rosa ◽  
Danilo Milardi
Keyword(s):  
Calcium Ions ◽  
Membrane Damage ◽  
Active Role ◽  
Membrane Disruption ◽  
Induced Membrane ◽  
Membrane Poration

Calcium ions inhibits Aβ induced membrane poration by small-sized oligomers but significantly foster fiber-dependent membrane disruption.

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