scholarly journals Semi‐quantitative Histology Confirms That The Macrophage is the Predominant Cell Type in Metal‐on‐Metal Hip Tissues

2021 ◽  
Author(s):  
Patricia Campbell ◽  
Sang‐Hyun Park ◽  
Edward Ebramzadeh
Keyword(s):  
Cell Type ◽  
Quantitative Histology ◽  
Metal On Metal ◽  
Predominant Cell Type

Osteosarcoma of the jaws: a literature review

2020 ◽  
Vol 16 ◽  
Author(s):  
Francesco Ricotta ◽  
Massimo Bassi ◽  
Nicola Tomasetti ◽  
Angelo Campobassi ◽  
Vincenzo Maiolo ◽  
...  
Keyword(s):  
Treatment Guidelines ◽  
State Of The Art ◽  
Bone Erosion ◽  
Tumor Resection ◽  
Bone Destruction ◽  
Cell Type ◽  
Complete Tumor Resection ◽  
Predominant Cell Type ◽  
Bone Changes ◽  
Complete Tumor

: Osteosarcoma of the jaws (OSJ) is a relatively rare disease, accounting for between 2% and 10% of all cases of osteosarcoma, it is morphologically and radiologically identical to the trunk and extremity variant, but distinct in several crucial aspects. : The lesion is characterized by sarcomatous cells which produces a variable amount of osteoid bone. It arises centrally within the bone and can be subdivided into osteoblastic, chondroblastic and fibroblastic subtype, depending on the predominant cell type. : Radiographically, these tumors display a spectrum of bone changes from well-demarcated borders to lytic bone destruction with indefinite margins and variable cortical bone erosion or, in some cases, images of sclerotic bone. Therapeutic options for OSJ include surgery, chemotherapy and radiotherapy, which are employed according to age of the patient, histological classification and localization of the tumor. Today there is no a general consensus in the treatment guidelines for the OSJ though surgery represents the key of the treatment. The main prognostic factor deeply influencing the patient's prognosis remains the complete tumor resection with negative surgical margins. : The aim of the present review is to describe the state of the art regarding diagnostic and surgical treatment aspects of the primary osteosarcoma of the jaws.

Identification, properties, and differential counts of cell populations using electron microscopy of dry cows secretions, colostrum and milk from normal cows

1980 ◽  
Vol 47 (1) ◽  
pp. 39-50 ◽  
Author(s):  
Chee-Seong Lee ◽  
F. B. Peter Wooding ◽  
Patrick Kemp
Keyword(s):  
Epithelial Cells ◽  
Plasma Cells ◽  
Polymorphonuclear Leucocyte ◽  
Polystyrene Latex ◽  
Cell Populations ◽  
Cell Type ◽  
Lactating Cows ◽  
Fresh Milk ◽  
Predominant Cell Type ◽  
Differential Counts

SummaryDifferential counts of electron microscope sections of cell pellets isolated from bovine udder secretions showed that no secretory epithelial cells and very few ductal epithelial cells were present at any stage. The predominant cell type was the macrophage in dry and lactating cows or the polymorphonuclear leucocyte (PMNL) in colostrum. Lymphocytes were also present but no plasma cells were found. The macrophages took up polystyrene latex particles (as did the PMNL) and adhered toglass in culture. Neither macrophage-nor PMNL-rich cell suspensions produced any increase in free fatty acid levels when incubated with fresh milk.

Carcinoma of the Nasal Septum: Experience with 85 Cases

1982 ◽  
Vol 90 (1) ◽  
pp. 90-94 ◽  
Author(s):  
Charles W. Beatty ◽  
Bruce W. Pearson ◽  
Eugene B. Kern
Keyword(s):  
Squamous Cell Carcinoma ◽  
Malignant Melanoma ◽  
Squamous Cell ◽  
Nasal Septum ◽  
Surgical Excision ◽  
Squamous Cell Carcinomas ◽  
Cell Type ◽  
Predominant Cell Type ◽  
Choice Of Treatment ◽  
Initial Choice

A review of 85 Mayo Clinic patients with carcinoma of the nasal septum revealed squamous cell carcinoma (58 patients) to be the predominant cell type, with adenocarcinoma (12 patients) and malignant melanoma (7 patients) being next in frequency. Twenty-five (29%) of the 85 patients had metastatic disease. Twenty percent (17) of the patients had another malignancy at some time during their lives. The study suggests that tobacco smoking may have a role in the etiology of squamous cell carcinomas of the nasal septum. In most patients, wide surgical excision was the initial choice of treatment.

Characterization of decorin mRNA in pregnant intrauterine tissues of the ewe and regulation by steroids

2000 ◽  
Vol 278 (1) ◽  
pp. C199-C206 ◽  
Author(s):  
Wen Xuan Wu ◽  
Qi Zhang ◽  
Nobuya Unno ◽  
Jan B. Derks ◽  
Peter W. Nathanielsz
Keyword(s):  
Northern Blot Analysis ◽  
Subtractive Hybridization ◽  
Late Gestation ◽  
Cell Type ◽  
Coding Region ◽  
Pregnant Sheep ◽  
Predominant Cell Type ◽  
The Matrix ◽  
Myometrial Contractility

In this study, we characterized the changes in the extracellular matrix proteoglycan decorin in pregnant intrauterine tissues in late gestation and in association with labor and delivery in sheep. In addition, we examined the effects of estradiol and progesterone on regulation of decorin mRNA expression in myometrium from the nonpregnant ovariectomized sheep. Using suppression subtractive hybridization in combination with Northern blot analysis, we identified a significant increase in decorin mRNA in the pregnant sheep myometrium during labor. The abundance of decorin mRNA paralleled myometrial contractility. The increase in decorin mRNA during labor was only demonstrated in the myometrium; no increase was observed in the endometrium or fetal membranes. Estradiol upregulated decorin mRNA and may act as a potential stimulator responsible for the increased decorin in the myometrium during parturition. The ovine decorin cDNA spans 1288 nt, includes 1083 nt of coding sequence predicted to encode a protein of 360 amino acids, 119 nt of 5′-untranslated region (UTR) and 86 nt of 3′-UTR. Over the coding region, the protein shares 79–96% nt sequence identity and 73–94% identity in the deduced amino acid sequence with homologous mammalian sequences. Using cloned decorin cDNA, we observed that the fibroblasts are the predominant cell type in the pregnant sheep myometrium containing decorin mRNA. These data suggest that increased decorin synthesis participates in the matrix changes that may play a role in myometrial activation.

SOME OBSERVATIONS ON THE ULTRASTRUCTURE OF THE ADENOHYPOPHYSIS OF THE RABBIT

1965 ◽  
Vol 31 (3) ◽  
pp. 279-287 ◽  
Author(s):  
B. A. YOUNG ◽  
C. L. FOSTER ◽  
E. CAMERON
Keyword(s):  
Granular Cell ◽  
Pars Intermedia ◽  
Pars Tuberalis ◽  
Pars Distalis ◽  
Cell Type ◽  
Cytoplasmic Rna ◽  
Large Numbers ◽  
Predominant Cell Type ◽  
Relationship Of ◽  
The Relationship

SUMMARY The ultrastructure of the adenohypophysis of the rabbit is described preliminary to reporting changes after experimental procedures. Fixation by perfusing with gluteraldehyde enabled selected regions of the gland to be removed with accuracy. Separate descriptions of the pars distalis proper, zona tuberalis, pars tuberalis and pars intermedia are therefore included. In the pars distalis proper four types of granular cell were recognized although their function cannot be accurately determined. For convenience, therefore, they have been designated 1, 2, 3 and 4. In addition a fifth type of cell (type 5) is described which is also present in the other areas. This cell, as well as having possible phagocytic functions, appears to be concerned in the formation of a perivascular channel. Two types of cell are recognized in the zona tuberalis, which are similar in appearance to the 3 and 4 cells of the pars distalis, although not necessarily identical in function. The characteristic cells of the pars tuberalis are rich in cytoplasmic RNA and contain large numbers of intracellular fibrils. It is suggested that the ribosomes are concerned in the synthesis of a sedentary protein which may take the form of the microfibrils. The pars intermedia contains a predominant cell type with large granules of varying density. The relationship of these granules to the specific hormone is discussed.

scholarly journals Fibroblasts in cancer dormancy: foe or friend?

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Li Dai ◽  
Mao Li ◽  
Wei-long Zhang ◽  
Ya-Jie Tang ◽  
Ya-ling Tang ◽  
...  
Keyword(s):  
Tumor Microenvironment ◽  
Tumor Cells ◽  
Cancer Metastasis ◽  
Cancer Associated Fibroblasts ◽  
Cell Type ◽  
Residual Cancer ◽  
Resistance To Therapy ◽  
Cancer Dormancy ◽  
Predominant Cell Type ◽  
Ultimate Fate

AbstractCancer dormancy is defined that the residual cancer cells could enter into a state of quiescence and patients remain asymptomatic for years or even decades after anti-tumor therapies. Fibroblasts, which represent a predominant cell type in tumor microenvironment, play a pivotal role in determining the ultimate fate of tumor cells. This review recapitulates the pleiotropic roles of fibroblasts which are divided into normal, senescent, cancer-associated fibroblasts (CAFs) and circulation CAFs in tumor dormancy, relapse, metastasis and resistance to therapy to help the treatment of cancer metastasis.

scholarly journals Systematic characterization of porcine ileal Peyer's patch, I. Apoptosis-sensitive immature B cells are the predominant cell type

Immunology ◽  
1999 ◽  
Vol 98 (4) ◽  
pp. 612-621 ◽  
Author(s):  
J. K. Andersen ◽  
H. Takamatsu ◽  
C. A. L. Oura ◽  
S. M. Brookes ◽  
L. Pullen ◽  
...  
Keyword(s):  
B Cells ◽  
Peyer’S Patch ◽  
Cell Type ◽  
Peyer's Patch ◽  
Predominant Cell Type ◽  
Immature B Cells

scholarly journals The Fine Structure of Lymphosarcoma in Cattle

1969 ◽  
Vol 6 (1) ◽  
pp. 15-29 ◽  
Author(s):  
Yuttaka Fujimoto ◽  
Janice Miller ◽  
C. Olson
Keyword(s):  
Endoplasmic Reticulum ◽  
Fine Structure ◽  
Tumor Cells ◽  
Multivesicular Bodies ◽  
Heterogeneous Mixture ◽  
Nuclear Inclusion ◽  
Cell Type ◽  
Lymphoid Tumor ◽  
Cytoplasmic Membranes ◽  
Predominant Cell Type

Nine cases of bovine lymphosarcoma were classified by light microscopy as lymphoid or reticulum according to the predominant cell type, or as lymphoreticular when there was a heterogeneous mixture of lymphoid and reticulum tumor cells. Typical ultrastructural features of these cells were as follows. Lymphoid tumor cells had smoothly contoured nuclear and cytoplasmic membranes and few cytoplasmic organelles. Reticulum tumor cells had large interchromatin spaces and irregular nuclear and cytoplasmic outlines. They often had multivesicular bodies, lysosomal vesicles, and much smooth-surfaced endoplasmic reticulum in the cytoplasm and were frequently surrounded by extracellular microfibrils and collagen libers. Nuclear inclusion-like masses of cytoplasm were common in both types of tumor cells. No structure was observed which could be recognized as virus.

scholarly journals The sarcoid granuloma: ‘epithelioid’ or ‘lymphocytic-epithelioid’ granuloma?

2012 ◽  
Vol 7 ◽  
Author(s):  
Zdravko Kosjerina ◽  
Bojan Zaric ◽  
Dejan Vuckovic ◽  
Dusan Lalosevic ◽  
Goran Djenadic ◽  
...  
Keyword(s):  
Plasma Cells ◽  
Giant Cells ◽  
Numerical Density ◽  
Cell Type ◽  
Epithelioid Cells ◽  
Stereological Method ◽  
Epithelioid Granuloma ◽  
Sarcoid Granuloma ◽  
Predominant Cell Type ◽  
The Mean

Background: This study aims to analyze the structure and quantities of cellular elements in sarcoid granulomas. Methods: We investigated 34 transbronchial lung biopsy samples obtained from 34 sarcoid patients. The quantity and composition of the cellular elements inside a granuloma were determined by the quantitative stereometry method, employing the numerical density as a stereological method. Results: A total of 102 sarcoid granulomas were analyzed. The central part of all granulomas was occupied by epithelioid cells. Besides these, giant cells, lymphocytes, macrophages and plasma cells were also seen. The mean numerical density of all the cells in the central part of a sarcoid granuloma was 111,751 mm-3. Lymphocytes prevailed in number, exceeding the total count of all other cells. With a mean numerical density of 74,321 mm-3, lymphocytes were twice as numerous as both epithelioid cells and macrophages with a mean numerical density of 37,193 mm-3. Conclusions: Lymphocytes are the predominant cell type in the central part of a sarcoid granuloma, significantly exceeding both epithelioid cells and macrophages in number, raising the question if the term “epithelioid granuloma”, routinely used to designate sarcoid granulomas, is correct, or if it would be more logical to call them “lymphocytic-epithelioid granulomas” instead. Trial registration: This study was supported by the Serbian Ministry of Science and Environmental Protection Grant Number 175006/2011.

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