scholarly journals Relationship of cytokine levels and clinical effect on platelet-rich plasma-treated lateral epicondylitis

2017 ◽  
Author(s):  
Wonbong Lim ◽  
Sang H. Park ◽  
Bora Kim ◽  
Sin W. Kang ◽  
Jung W. Lee ◽  
...  
Keyword(s):  
Clinical Effect ◽  
Platelet Rich Plasma ◽  
Lateral Epicondylitis ◽  
Cytokine Levels ◽  
Relationship Of

scholarly journals Effects of intralesional platelet-rich plasma in the patients with lateral epicondylitis of elbow

2019 ◽  
Vol 12 (3) ◽  
pp. 138-141
Author(s):  
Mohammad Tariqul Islam ◽  
M. A. Shakoor ◽  
Afsana Mahjabin ◽  
Md. Ali Emran
Keyword(s):  
Visual Analogue Scale ◽  
Daily Living ◽  
Analogue Scale ◽  
Tennis Elbow ◽  
Platelet Rich Plasma ◽  
Lateral Epicondylitis ◽  
Activity Of Daily Living ◽  
Evaluation Tool ◽  
Plasma Injection ◽  
The Difference

Lateral epicondylitis (tennis elbow) is a major cause of musculoskeletal pain involving common extensor origin of the forearm. This study was done to determine the effects of platelet-rich plasma on 15 patients with lateral epicondylitis. Selected patients were given intralesional platelet-rich plasma injection, activity of daily living instructions and paracetamol. Patients were assessed every 14 days interval by visual analogue scale, and the patient rated tennis elbow evaluation. Treatment response according to visual analogue scale and patient rated tennis elbow evaluation tool, the difference of improvement was found in respect to time, from pretreatment W1 (just before 1st Intervention) score to W11 score in every alternate week (p<0.005). This indicates that intralesional platelet-rich plasma is effective in the patients with lateral epicondylitis of elbow.

scholarly journals Proplatelets and stress platelets

Blood ◽  
1987 ◽  
Vol 69 (2) ◽  
pp. 522-528 ◽  
Author(s):  
M Tong ◽  
P Seth ◽  
DG Penington
Keyword(s):  
Bone Marrow ◽  
Platelet Rich Plasma ◽  
Early Period ◽  
Platelet Volume ◽  
Plasma Exposure ◽  
Functional Characteristics ◽  
Platelet Production ◽  
Relationship Of ◽  
The Relationship ◽  
Platelet Formation

Abstract The process of platelet formation by the fragmentation of megakaryocyte pseudopodia, termed proplatelets, demonstrable in the marrow sinusoids is poorly understood. “Stress” platelets produced under conditions of stimulated platelet production differ from normal circulating platelets with respect to volume and a number of functional characteristics. To clarify the relationship of stress platelets to proplatelets, rats were injected with heterologous platelet antiserum. Nondiscoid platelet forms, some characteristically beaded in appearance, strongly resembling bone marrow proplatelets, can be recovered in the circulation of normal rats. During the early period of recovery from acute thrombocytopenia, there was a substantial increase in the proportion of these elongated platelets in the citrated platelet rich plasma. Exposure to EDTA rendered them spherical. Circulating proplatelets may contribute significantly to the prompt increase in platelet volume during recovery from acute thrombocytopenia at a time prior to significant increase in megakaryocyte size and ploidy.

Platelet-rich plasma versus Tenex in the treatment of medial and lateral epicondylitis

2019 ◽  
Vol 28 (1) ◽  
pp. 112-119 ◽  
Author(s):  
Allison L. Boden ◽  
Michael T. Scott ◽  
Poonam P. Dalwadi ◽  
Kenneth Mautner ◽  
R. Amadeus Mason ◽  
...  
Keyword(s):  
Platelet Rich Plasma ◽  
Lateral Epicondylitis

scholarly journals Effect of Platelet-Rich Plasma (PRP) versus Autologous Whole Blood on Pain and Function Improvement in Tennis Elbow: A Randomized Clinical Trial

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Seyed Ahmad Raeissadat ◽  
Leyla Sedighipour ◽  
Seyed Mansoor Rayegani ◽  
Mohammad Hasan Bahrami ◽  
Masume Bayat ◽  
...  
Keyword(s):  
Whole Blood ◽  
Tennis Elbow ◽  
Platelet Rich Plasma ◽  
Autologous Blood ◽  
Pressure Pain Threshold ◽  
Lateral Epicondylitis ◽  
Autologous Whole Blood ◽  
Significant Difference ◽  
Group 2 ◽  
And Function

Background. Autologous whole blood and platelet-rich plasma (PRP) have been both suggested to treat chronic tennis elbow. The aim of the present study was to compare the effects of PRP versus autologous whole blood local injection in chronic tennis elbow. Methods. Forty patients with tennis elbow were randomly divided into 2 groups. Group 1 was treated with a single injection of 2 mL of autologous PRP and group 2 with 2 mL of autologous blood. Tennis elbow strap, stretching, and strengthening exercises were administered for both groups during a 2-month followup. Pain and functional improvements were assessed using visual analog scale (VAS), modified Mayo Clinic performance index for the elbow, and pressure pain threshold (PPT) at 0, 4, and 8 weeks. Results. All pain and functional variables including VAS, PPT, and Mayo scores improved significantly in both groups 4 weeks after injection. No statistically significant difference was noted between groups regarding pain scores in 4-week follow-up examination (P>0.05). At 8-week reevaluations, VAS and Mayo scores improved only in PRP group (P<0.05). Conclusion. PRP and autologous whole blood injections are both effective to treat chronic lateral epicondylitis. PRP might be slightly superior in 8-week followup. However, further studies are suggested to get definite conclusion.

scholarly journals STUDY COMPARING THE EFFICACY OF PLATELET RICH PLASMA VERSUS TRIAMCINOLONE IN TREATING TENNIS ELBOW

2019 ◽  
Vol 3 (7) ◽  
Author(s):  
Pratush Kumar Goyal ◽  
Anil Kumar Pandey ◽  
Akhil Bansal ◽  
Mohammad Zuber
Keyword(s):  
Tennis Elbow ◽  
Platelet Rich Plasma ◽  
Randomized Study ◽  
Lateral Epicondylitis ◽  
Age Group ◽  
Elbow Pain ◽  
Therapy Assessment ◽  
Pre Treatment ◽  
Gandhi Medical College ◽  
Group 1

Background: Lateral epicondylitis is seen more commonly in non-athletes than athletes. Non-operative methods are the mainstay of treatment being effective in more than 95% of cases. Platelet rich plasma (PRP) has shown promising results in many studies as compared to steroid injection & other modes of conservative management. Hence, this study was done to evaluate PRP efficacy in our clinical setup and in the people of age group most commonly being affected. Methods: This randomized study was conducted at Gandhi Medical College & Hamidia Hospital, Bhopal, for a period of two years from Aug 2015 to Sep 2017 on 60 consenting patients diagnosed as suffering from lateral epicondylitis. Using lottery method for randomization the patients were divided into two groups, based on which the treatment was received. Group –1 with 30 patients received 2 ml of PRP. Group –2 with 30 patients received 2 ml of Triamcinolone injection. The data collected and recorded in the appropriate proforma. Post therapy assessment was done using with Oxford elbow score. Results:  Average age at presentation was 31.11 years, Range of age was from 20 to 40 years. Maximum incidence was in the age group of 35 to 40 years. Female preponderance was observed in Group 1. Most common presenting complaint was elbow pain seen in 100% of cases. Most common side involved was the dominant side right side involvement was seen in 41 cases and left side in 19 cases. The Oxford elbow score pre-treatment in all the groups was not statistically significant and the Oxford elbow score at the end of 6 weeks,12 weeks and 24 weeks treatment showed that PRP is better than  steroid  in control of pain. Conclusion: Lateral epicondylitis/Tennis elbow is a painful debilitating condition of elbow, which creates disturbance in functional activities. A single injection of PRP at the site of the elbow pain resulted in relief of pain in patients with longer duration as compared to local steroids to other conservative treatments. Keywords: Tennis elbow, Platelet rich plasma, Steroid, Triamcinolone, Lateral epicondylitis

scholarly journals Platelet rich plasma versus laser therapy in lateral epicondylitis of elbow

2014 ◽  
Vol 48 (4) ◽  
pp. 390 ◽  
Author(s):  
Gyaneshwar Tonk ◽  
Anish Kumar ◽  
Amit Gupta
Keyword(s):  
Laser Therapy ◽  
Platelet Rich Plasma ◽  
Lateral Epicondylitis
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