In vivo diagnostics of human knee cartilage lesions using delayed CBCT arthrography

2013 ◽  
Vol 32 (3) ◽  
pp. 403-412 ◽  
Author(s):  
Harri T. Kokkonen ◽  
Juha-Sampo Suomalainen ◽  
Antti Joukainen ◽  
Heikki Kröger ◽  
Joonas Sirola ◽  
...  
Keyword(s):  
Knee Cartilage ◽  
Human Knee ◽  
Cartilage Lesions ◽  
In Vivo Diagnostics

scholarly journals Role of Scaffolds, Subchondral, Intra-Articular Injections of Fresh Autologous Bone Marrow Concentrate Regenerative Cells in Treating Human Knee Cartilage Lesions: Different Approaches and Different Results

2021 ◽  
Vol 22 (8) ◽  
pp. 3844
Author(s):  
Jacques Hernigou ◽  
Pascale Vertongen ◽  
Joanne Rasschaert ◽  
Philippe Hernigou
Keyword(s):  
Bone Marrow ◽  
Subchondral Bone ◽  
Bone Marrow Aspirate ◽  
Autologous Bone Marrow ◽  
Long Term Results ◽  
Knee Cartilage ◽  
Human Knee ◽  
Cartilage Lesions ◽  
Autologous Bone

The value of bone marrow aspirate concentrates for treatment of human knee cartilage lesions is unclear. Most of the studies were performed with intra-articular injections. However, subchondral bone plays an important role in the progression of osteoarthritis. We investigated by a literature review whether joint, subchondral bone, or/and scaffolds implantation of fresh autologous bone marrow aspirate concentrated (BMAC) containing mesenchymal stem cells (MSCs) would improve osteoarthritis (OA). There is in vivo evidence that suggests that all these different approaches (intra-articular injections, subchondral implantation, scaffolds loaded with BMAC) can improve the patient. This review analyzes the evidence for each different approach to treat OA. We found that the use of intra-articular injections resulted in a significant relief of pain symptoms in the short term and was maintained in 12 months. However, the clinical trials indicate that the application of autologous bone marrow concentrates in combination with scaffolds or in injection in the subchondral bone was superior to intra-articular injection for long-term results. The tendency of MSCs to differentiate into fibrocartilage affecting the outcome was a common issue faced by all the studies when biopsies were performed, except for scaffolds implantation in which some hyaline cartilage was found. The review suggests also that both implantation of subchondral BMAC and scaffolds loaded with BMAC could reduce the need for further surgery.

In vivo MRI analysis of depth-dependent ultrastructure in human knee cartilage at 7 T

2013 ◽  
Vol 26 (11) ◽  
pp. 1412-1419 ◽  
Author(s):  
Nikita Garnov ◽  
Wilfried Gründer ◽  
Gregor Thörmer ◽  
Robert Trampel ◽  
Robert Turner ◽  
...  
Keyword(s):  
Knee Cartilage ◽  
Human Knee

scholarly journals Vessel architecture in human knee cartilage in children: an in vivo susceptibility-weighted imaging study at 7 T

2018 ◽  
Vol 28 (8) ◽  
pp. 3384-3392 ◽  
Author(s):  
Alexander Kolb ◽  
Simon Robinson ◽  
David Stelzeneder ◽  
Markus Schreiner ◽  
Catharina Chiari ◽  
...  
Keyword(s):  
Imaging Study ◽  
Susceptibility Weighted Imaging ◽  
Knee Cartilage ◽  
Human Knee

scholarly journals 412 IN VIVO TRANSPORT OF GD-DTPA2− IN HUMAN KNEE CARTILAGE ASSESSED BY DEPTH-WISE DGEMRIC ANALYSIS

2010 ◽  
Vol 18 ◽  
pp. S182-S183
Author(s):  
Z.K. Hawezi ◽  
C.J. Tiderius ◽  
J. Svensson ◽  
L.E. Dahlberg ◽  
E. Lammentausta
Keyword(s):  
Knee Cartilage ◽  
Human Knee

scholarly journals 384 SENSITIVITY OF CEST MRI OF HUMAN KNEE CARTILAGE IN VIVO AT3TAND7T

2011 ◽  
Vol 19 ◽  
pp. S177
Author(s):  
M. Haris ◽  
A. Singh ◽  
V. Kassey ◽  
K. Cai ◽  
D. Reddy ◽  
...  
Keyword(s):  
Knee Cartilage ◽  
Human Knee ◽  
Cest Mri

In vivo transport of Gd-DTPA2− in human knee cartilage assessed by depth-wise dGEMRIC analysis

2011 ◽  
Vol 34 (6) ◽  
pp. 1352-1358 ◽  
Author(s):  
Zana K. Hawezi ◽  
Eveliina Lammentausta ◽  
Jonas Svensson ◽  
Leif E. Dahlberg ◽  
Carl J. Tiderius
Keyword(s):  
Knee Cartilage ◽  
Human Knee

scholarly journals High quality three‐dimensional gagCEST imaging of in vivo human knee cartilage at 7 Tesla

2016 ◽  
Vol 77 (5) ◽  
pp. 1866-1873 ◽  
Author(s):  
Guruprasad Krishnamoorthy ◽  
Ravi Prakash Reddy Nanga ◽  
Puneet Bagga ◽  
Hari Hariharan ◽  
Ravinder Reddy
Keyword(s):  
Three Dimensional ◽  
7 Tesla ◽  
Knee Cartilage ◽  
High Quality ◽  
Human Knee

Ultrasound Arthroscopy of Human Knee Cartilage and Subchondral Bone in Vivo

2014 ◽  
Vol 40 (9) ◽  
pp. 2039-2047 ◽  
Author(s):  
Jukka Liukkonen ◽  
Petri Lehenkari ◽  
Jukka Hirvasniemi ◽  
Antti Joukainen ◽  
Tuomas Virén ◽  
...  
Keyword(s):  
Subchondral Bone ◽  
Knee Cartilage ◽  
Human Knee
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