Signaling through the small G-protein Cdc42 is involved in insulin-like growth factor-I resistance in aging articular chondrocytes

Lisa A. Fortier; Brian J. Miller

doi:10.1002/jor.20185

Signaling through the small G-protein Cdc42 is involved in insulin-like growth factor-I resistance in aging articular chondrocytes

Journal of Orthopaedic Research® ◽

10.1002/jor.20185 ◽

2006 ◽

Vol 24 (8) ◽

pp. 1765-1772 ◽

Cited By ~ 14

Author(s):

Lisa A. Fortier ◽

Brian J. Miller

Keyword(s):

Growth Factor ◽

G Protein ◽

Articular Chondrocytes ◽

Insulin Like Growth Factor ◽

Factor I ◽

Small G Protein ◽

Growth Factor I

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Insulin-like growth factor-I diminishes the activation status and expression of the small GTPase Cdc42 in articular chondrocytes

Journal of Orthopaedic Research® ◽

10.1016/j.orthres.2003.08.021 ◽

2004 ◽

Vol 22 (2) ◽

pp. 436-445 ◽

Cited By ~ 14

Author(s):

Lisa A. Fortier ◽

Molly M. Deak ◽

Stacy A. Semevolos ◽

Richard A. Cerione

Keyword(s):

Growth Factor ◽

Articular Chondrocytes ◽

Small Gtpase ◽

Insulin Like Growth Factor ◽

Factor I ◽

Growth Factor I ◽

Activation Status

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Alginate Encapsulation Impacts the Insulin-like Growth Factor-I System of Monolayer-Expanded Equine Articular Chondrocytes and Cell Response to Interleukin-1β

Tissue Engineering ◽

10.1089/ten.2006.0345 ◽

2007 ◽

Vol 13 (6) ◽

pp. 1333-1345 ◽

Cited By ~ 7

Author(s):

Ryan M. Porter ◽

R. Michael Akers ◽

Rick D. Howard ◽

Kimberly Forsten-Williams

Keyword(s):

Growth Factor ◽

Cell Response ◽

Articular Chondrocytes ◽

Interleukin 1Β ◽

Insulin Like Growth Factor ◽

Alginate Encapsulation ◽

Factor I ◽

Growth Factor I

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Effects of interleukin-1 beta on insulin-like growth factor-I autocrine/paracrine axis in cultured rat articular chondrocytes.

Annals of the Rheumatic Diseases ◽

10.1136/ard.53.2.128 ◽

1994 ◽

Vol 53 (2) ◽

pp. 128-133 ◽

Cited By ~ 27

Author(s):

T Matsumoto ◽

T Tsukazaki ◽

H Enomoto ◽

K Iwasaki ◽

S Yamashita

Keyword(s):

Growth Factor ◽

Articular Chondrocytes ◽

Interleukin 1 ◽

Insulin Like Growth Factor ◽

Interleukin 1 Beta ◽

Factor I ◽

Growth Factor I

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Insulin and Insulin-like Growth Factor I Receptors Utilize Different G Protein Signaling Components

Journal of Biological Chemistry ◽

10.1074/jbc.m010884200 ◽

2001 ◽

Vol 276 (19) ◽

pp. 15688-15695 ◽

Cited By ~ 114

Author(s):

Stephane Dalle ◽

William Ricketts ◽

Takeshi Imamura ◽

Peter Vollenweider ◽

Jerrold M. Olefsky

Keyword(s):

Growth Factor ◽

G Protein ◽

G Protein Signaling ◽

Insulin Like Growth Factor ◽

Protein Signaling ◽

Factor I ◽

Growth Factor I ◽

Signaling Components

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Effect of Transforming Growth Factor-β on the Insulin-like Growth Factor-I Autocrine/Paracrine Axis in Cultured Rat Articular Chondrocytes

Experimental Cell Research ◽

10.1006/excr.1994.1307 ◽

1994 ◽

Vol 215 (1) ◽

pp. 9-16 ◽

Cited By ~ 64

Author(s):

Tomoo Tsukazaki ◽

Toshiro Usa ◽

Tomoko Matsumoto ◽

Hiroshi Enomoto ◽

Akira Ohtsuru ◽

...

Keyword(s):

Growth Factor ◽

Transforming Growth Factor ◽

Articular Chondrocytes ◽

Transforming Growth Factor Β ◽

Insulin Like Growth Factor ◽

Factor I ◽

Growth Factor I

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Transcriptional and proteolytic regulation of the insulin-like growth factor-I system of equine articular chondrocytes by recombinant equine interleukin-1β

Journal of Cellular Physiology ◽

10.1002/jcp.20762 ◽

2006 ◽

Vol 209 (2) ◽

pp. 542-550 ◽

Cited By ~ 4

Author(s):

Ryan M. Porter ◽

R. Michael Akers ◽

Rick D. Howard ◽

Kimberly Forsten-Williams

Keyword(s):

Growth Factor ◽

Articular Chondrocytes ◽

Interleukin 1Β ◽

Insulin Like Growth Factor ◽

Factor I ◽

Growth Factor I

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Growth hormone stimulates insulin-like growth factor I actions on adult articular chondrocytes

Journal of Orthopaedic Research® ◽

10.1002/jor.1100070207 ◽

1989 ◽

Vol 7 (2) ◽

pp. 198-207 ◽

Cited By ~ 21

Author(s):

R. Lane Smith ◽

Marykutty V. Palathumpat ◽

Christine W. Ku ◽

Raymond L. Hintz

Keyword(s):

Growth Hormone ◽

Growth Factor ◽

Articular Chondrocytes ◽

Insulin Like Growth Factor ◽

Factor I ◽

Growth Factor I

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Posttranscriptional effect of insulin-like growth factor-I on interleukin-1beta-induced type II-secreted phospholipase A2 gene expression in rabbit articular chondrocytes.

Journal of Clinical Investigation ◽

10.1172/jci119353 ◽

1997 ◽

Vol 99 (8) ◽

pp. 1864-1872 ◽

Cited By ~ 34

Author(s):

C Jacques ◽

G Béréziat ◽

L Humbert ◽

J L Olivier ◽

M T Corvol ◽

...

Keyword(s):

Gene Expression ◽

Growth Factor ◽

Phospholipase A2 ◽

Articular Chondrocytes ◽

Insulin Like Growth Factor ◽

Type Ii ◽

Factor I ◽

Secreted Phospholipase A2 ◽

Growth Factor I ◽

Rabbit Articular Chondrocytes

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Prostaglandin E2 stimulates incorporation of proline into collagenase digestible proteins in human articular chondrocytes: identification of an effector autocrine loop involving insulin-like growth factor I

Molecular and Cellular Endocrinology ◽

10.1016/0303-7207(96)03887-7 ◽

1996 ◽

Vol 123 (1) ◽

pp. 27-35 ◽

Cited By ~ 24

Author(s):

J.A. Di Battista ◽

S. Doré ◽

J. Martel-Pelletier ◽

J.-P. Pelletier

Keyword(s):

Growth Factor ◽

Prostaglandin E2 ◽

Articular Chondrocytes ◽

Human Articular Chondrocytes ◽

Insulin Like Growth Factor ◽

Autocrine Loop ◽

Factor I ◽

Growth Factor I

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Effect of Somatomedin-C/Insulin-Like Growth Factor I and Growth Hormone on Cultured Growth Plate and Articular Chondrocytes

Pediatric Research ◽

10.1203/00006450-198901000-00017 ◽

1989 ◽

Vol 25 (1) ◽

pp. 76-82 ◽

Cited By ~ 100

Author(s):

S B Trippel ◽

M T Corvol ◽

M F Dumontier ◽

R Rappaport ◽

H H Hung ◽

...

Keyword(s):

Growth Hormone ◽

Growth Factor ◽

Growth Plate ◽

Articular Chondrocytes ◽

Insulin Like Growth Factor ◽

Somatomedin C ◽

Factor I ◽

Growth Factor I

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