Localization and partial characterization of a 60 kDa citrulline-containing transport form of myelin basic protein from MO3-13 cells and human white matter

1995 ◽  
Vol 42 (1) ◽  
pp. 41-53 ◽  
Author(s):  
M. R. M. Ursell ◽  
J. McLaurin ◽  
D. D. Wood ◽  
C. A. Ackerley ◽  
M. A. Moscarello ◽  
...  
Keyword(s):  
White Matter ◽  
Myelin Basic Protein ◽  
Basic Protein ◽  
Partial Characterization ◽  
Transport Form

Myelin basic protein: Structural characterization of spherulites formation and preventive action of trehalose

2013 ◽  
Vol 57 ◽  
pp. 63-68 ◽  
Author(s):  
Cinzia Di Salvo ◽  
Davide Barreca ◽  
Giuseppina Laganà ◽  
Marcella di Bella ◽  
Ester Tellone ◽  
...  
Keyword(s):  
Myelin Basic Protein ◽  
Structural Characterization ◽  
Basic Protein ◽  
Preventive Action

scholarly journals How long is sufficient for optimal neuroprotection with cerebral cooling after ischemia in fetal sheep?

2017 ◽  
Vol 38 (6) ◽  
pp. 1047-1059 ◽  
Author(s):  
Joanne O Davidson ◽  
Vittoria Draghi ◽  
Sean Whitham ◽  
Simerdeep K Dhillon ◽  
Guido Wassink ◽  
...  
Keyword(s):  
White Matter ◽  
Cerebral Ischemia ◽  
Myelin Basic Protein ◽  
Basic Protein ◽  
Close Association ◽  
Global Cerebral Ischemia ◽  
Fetal Sheep ◽  
Head Cooling ◽  
Improved Outcomes ◽  
Eeg Power

The optimal duration of mild “therapeutic” hypothermia for neonates with hypoxic-ischemic encephalopathy is surprisingly unclear. This study assessed the relative efficacy of cooling for 48 h versus 72 h. Fetal sheep (0.85 gestation) received sham ischemia (n = 9) or 30 min global cerebral ischemia followed by normothermia (n = 8) or delayed hypothermia from 3 h to 48 h (n = 8) or 72 h (n = 8). Ischemia was associated with profound loss of electroencephalogram (EEG) power, neurons in the cortex and hippocampus, and oligodendrocytes and myelin basic protein expression in the white matter, with increased Iba-1-positive microglia and proliferation. Hypothermia for 48 h was associated with improved outcomes compared to normothermia, but a progressive deterioration of EEG power after rewarming compared to 72 h of hypothermia, with impaired neuronal survival and myelin basic protein, and more microglia in the white matter and cortex. These findings show that head cooling for 48 h is partially neuroprotective, but is inferior to cooling for 72 h after cerebral ischemia in fetal sheep. The close association between rewarming at 48 h, subsequent deterioration in EEG power and increased cortical inflammation strongly suggests that deleterious inflammation can be reactivated by premature rewarming.

Purification and spectroscopic characterization of the recombinant BG21 isoform of murine golli myelin basic protein

2007 ◽  
Vol 85 (2) ◽  
pp. 272-284 ◽  
Author(s):  
Vladimir V. Bamm ◽  
Mumdooh A.M. Ahmed ◽  
Vladimir Ladizhansky ◽  
George Harauz
Keyword(s):  
Myelin Basic Protein ◽  
Basic Protein ◽  
Spectroscopic Characterization

Physicochemical characterization of dodecylphosphocholine/palmitoyllysophosphatidic acid/myelin basic protein complexes

Biochemistry ◽  
1991 ◽  
Vol 30 (26) ◽  
pp. 6509-6516 ◽  
Author(s):  
George L. Mendz ◽  
David J. Miller ◽  
Ian M. Jamie ◽  
John W. White ◽  
Larry R. Brown ◽  
...  
Keyword(s):  
Myelin Basic Protein ◽  
Basic Protein ◽  
Protein Complexes ◽  
Physicochemical Characterization

Cloning and characterization of the rat myelin basic protein gene promoter

Gene ◽  
2003 ◽  
Vol 313 ◽  
pp. 161-167 ◽  
Author(s):  
Qiou Wei ◽  
W.Keith Miskimins ◽  
Robin Miskimins
Keyword(s):  
Myelin Basic Protein ◽  
Basic Protein ◽  
Protein Gene ◽  
Gene Promoter ◽  
Myelin Basic Protein Gene
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