Long-lasting neuroprotective effect of sildenafil against 3,4-methylenedioxymethamphetamine- induced 5-hydroxytryptamine deficits in the rat brain

2011 ◽  
Vol 90 (2) ◽  
pp. 518-528 ◽  
Author(s):  
Elena Puerta ◽  
Lucia Barros-Miñones ◽  
Isabel Hervias ◽  
Violeta Gomez-Rodriguez ◽  
Lourdes Orejana ◽  
...  
Keyword(s):  
Rat Brain ◽  
Neuroprotective Effect

Neuroprotective effect of aminoguanidine on transient focal ischaemia in the rat brain

2001 ◽  
Vol 905 (1-2) ◽  
pp. 91-103 ◽  
Author(s):  
Diana Cash ◽  
John S Beech ◽  
Richard C Rayne ◽  
Philip M.W Bath ◽  
Brian S Meldrum ◽  
...  
Keyword(s):  
Rat Brain ◽  
Neuroprotective Effect ◽  
Focal Ischaemia

scholarly journals Cathodal tDCS exerts neuroprotective effect in rat brain after acute ischemic stroke

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Ke-Ying Zhang ◽  
Gang Rui ◽  
Jun-Ping Zhang ◽  
Ling Guo ◽  
Guang-Zhou An ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Rat Brain ◽  
Neuroprotective Effect ◽  
Cathodal Tdcs

Glucosamine exerts a neuroprotective effect via suppression of inflammation in rat brain ischemia/reperfusion injury

Glia ◽  
2010 ◽  
Vol 58 (15) ◽  
pp. 1881-1892 ◽  
Author(s):  
So-Young Hwang ◽  
Joo-Hyun Shin ◽  
Ji-Sun Hwang ◽  
Song-Yi Kim ◽  
Jin-A Shin ◽  
...  
Keyword(s):  
Reperfusion Injury ◽  
Rat Brain ◽  
Brain Ischemia ◽  
Ischemia Reperfusion Injury ◽  
Neuroprotective Effect ◽  
Ischemia Reperfusion

Potential neuroprotective effect of γ-glutamylcysteine ethyl ester on rat brain against kainic acid-induced excitotoxicity

2010 ◽  
Vol 44 (5) ◽  
pp. 513-521 ◽  
Author(s):  
Ayfer Yalcin ◽  
Guliz Armagan ◽  
Ezgi Turunc ◽  
Sibel Konyalioglu ◽  
Lutfiye Kanit
Keyword(s):  
Rat Brain ◽  
Ethyl Ester ◽  
Kainic Acid ◽  
Neuroprotective Effect

Neuroprotective effect ofManasamitra vatakamagainst aluminium induced cognitive impairment and oxidative damage in the cortex and hippocampus of rat brain

2011 ◽  
Vol 35 (1) ◽  
pp. 104-115 ◽  
Author(s):  
Sathiravada Veerasamy Thirunavukkarasu ◽  
Subramanium Venkataraman ◽  
Sundararajan Raja ◽  
Lokesh Upadhyay
Keyword(s):  
Cognitive Impairment ◽  
Oxidative Damage ◽  
Rat Brain ◽  
Neuroprotective Effect

scholarly journals Antioxidative Activity of Ferrocenes Bearing 2,6-Di-Tert-Butylphenol Moieties

2010 ◽  
Vol 2010 ◽  
pp. 1-6 ◽  
Author(s):  
E. R. Milaeva ◽  
S. I. Filimonova ◽  
N. N. Meleshonkova ◽  
L. G. Dubova ◽  
E. F. Shevtsova ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Rat Brain ◽  
Antioxidative Activity ◽  
Neuroprotective Effect ◽  
In Vitro Study ◽  
Brain Homogenate ◽  
Liver Mitochondria ◽  
Rat Liver Mitochondria ◽  
Calcium Dependent

The antioxidative activity of ferrocenes bearing either 2,6-di-tert-butylphenol or phenyl groups has been compared using DPPH (1,1-diphenyl-2-picrylhydrazyl) test and in the study of the in vitro impact on lipid peroxidation in rat brain homogenate and on some characteristics of rat liver mitochondria. The results of DPPH test at20∘C show that the activity depends strongly upon the presence of phenolic group but is improved by the influence of ferrocenyl fragment. The activity of N-(3,5-di-tert-butyl-4-hydroxyphenyl)iminomethylferrocene (1), for instance, was 88.4%, which was higher than the activity of a known antioxidant 2,6-di-tert-butyl-4-methylphenol (BHT) (48.5%), whereas the activity of N-phenyl-iminomethylferrocene2was almost negligible−2.9%. The data obtained demonstrate that the compounds with 2,6-di-tert-butylphenol moiety are significantly more active than the corresponding phenyl analogues in the in vitro study of lipid peroxidation in rat brain homogenate. Ferrocene1performs a promising behavior as an antioxidant and inhibits the calcium-dependent swelling of mitochondria. These results allow us to propose the potential cytoprotective (neuroprotective) effect of ditopic compounds containing antioxidant 2,6-di-tert-butylphenol group and redox active ferrocene fragment.

Neuroprotective effect of grape seed and skin extract on lithium-induced oxidative stress in healthy rat brain

2017 ◽  
Vol 11 (1) ◽  
pp. 85-94 ◽  
Author(s):  
Ali Mezni ◽  
Hanène Aoua ◽  
Ferid Limam ◽  
Ezzedine Aouani
Keyword(s):  
Oxidative Stress ◽  
Rat Brain ◽  
Neuroprotective Effect ◽  
Grape Seed ◽  
Skin Extract
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