Acute pain and postherpetic neuralgia related to Varicella zoster virus reactivation: Comparison between typical herpes zoster and zoster sine herpete

2018 ◽  
Vol 91 (2) ◽  
pp. 287-295 ◽  
Author(s):  
Francesco Drago ◽  
Astrid Herzum ◽  
Giulia Ciccarese ◽  
Francesco Broccolo ◽  
Alfredo Rebora ◽  
...  
Keyword(s):  
Herpes Zoster ◽  
Varicella Zoster Virus ◽  
Acute Pain ◽  
Postherpetic Neuralgia ◽  
Virus Reactivation ◽  
Varicella Zoster ◽  
Zoster Sine Herpete

scholarly journals Herpes Zoster involving Trigeminal Nerve

2012 ◽  
Vol 2 (1) ◽  
pp. 50-52
Author(s):  
Rohit B Gadda ◽  
Neha Patil ◽  
Rohini Salvi
Keyword(s):  
Quality Of Life ◽  
Herpes Zoster ◽  
Viral Infection ◽  
Varicella Zoster Virus ◽  
Acute Pain ◽  
Healthy Male ◽  
Prodromal Symptoms ◽  
Varicella Zoster ◽  
Acute Viral Infection

Abstract Herpes zoster is a common acute viral infection caused by reactivation of Varicella-Zoster virus. Acute pain of herpes zoster lowers the quality of life and interferes with day to day activities. We report a case of herpes zoster in a 68 year old, healthy male patient in which the prodromal symptoms started as toothache. This case highlights the importance of a thorough dental history and examination in patients with toothache.

scholarly journals Kestabilan Model Matematika Infeksi Primer Penyakit Varicella Dan Infeksi Rekuren Penyakit Herpes Zoster Oleh Virus Varicella Zoster

2020 ◽  
Vol 17 (1) ◽  
pp. 82-91
Author(s):  
Hardiyanti ◽  
R Ratianingsih ◽  
Hajar
Keyword(s):  
Herpes Zoster ◽  
Stability Analysis ◽  
Varicella Zoster Virus ◽  
Critical Point ◽  
Postherpetic Neuralgia ◽  
Primary Infection ◽  
Skin Diseases ◽  
Varicella Zoster ◽  
Stable Conditions ◽  
Disease Free

Varicella and herpes zoster are two infectious skin diseases of human that caused by varicella zoster virus, where varicella disease is a primary infection that often infected younger people while herpes zoster disease is a recurrent disease that often infected older people because of reactivation of latent varicella-zoster virus. If the pain caused by herpes zoster after recurrent phase is a appeared then the condition is known as postherpetic neuralgia. This study builds a mathematical model of primary infection (varicella disease) and recurrent infection (herpes zoster disease) developed from the SIR model (Susceptible, Infected, Recovered). The human population is divided into seven subpopulations, namely susceptible, infection, recovered of varicella, herpes zoster and postherpetic neuralgia subpopulation. Stability analysis at the critical point by linearization method gives a critical point 𝑇1 that guaranted to exist and unstable if 𝛼 𝜇(𝛽1+𝜇) 𝐴 , while the critical point 𝑇1 does not have any reqruitment. Stability analysis at the endemic disease-free critical point is represented 𝑇1 that will be unstable if 𝑇2 exist and stable 𝑇1 if 𝑇2 exist. Numerical simulations by simulated to describe such temporary disease-free conditions and an endemic stable conditions.

scholarly journals Herpes Zoster Infection Presenting as Aseptic Meningitis and Dermatomal Rash in Immunocompetent Adult

2020 ◽  
Vol 2020 ◽  
pp. 1-3 ◽  
Author(s):  
Suyash Dawadi ◽  
Sudesh Lamsal ◽  
Bhupendra Shah
Keyword(s):  
Herpes Zoster ◽  
Varicella Zoster Virus ◽  
Aseptic Meningitis ◽  
Elderly Population ◽  
Virus Reactivation ◽  
Herpes Zoster Infection ◽  
Immunocompetent Adult ◽  
Varicella Zoster ◽  
Vesicular Rash ◽  
Immunocompromised Status

Herpes zoster is a localized, painful, and vesicular rash involving one or adjacent dermatomes caused by varicella-zoster virus reactivation. Herpes zoster presenting as aseptic meningitis is prevalent among elderly population and people with immunocompromised status. However, it is a rare phenomenon in the young immunocompetent adult; hence, we are reporting a case of a herpes zoster infection presenting as aseptic meningitis and dermatological manifestation in a 19-year-old immunocompetent male.

scholarly journals Herpes Zoster and Postherpetic Neuralgia: Past, Present and Future

2009 ◽  
Vol 14 (4) ◽  
pp. 275-282 ◽  
Author(s):  
Gary J Bennett ◽  
C Peter N Watson
Keyword(s):  
Herpes Zoster ◽  
Varicella Zoster Virus ◽  
Recent Work ◽  
Postherpetic Neuralgia ◽  
Current Understanding ◽  
Varicella Zoster

OBJECTIVES: The history behind the current understanding of the varicella-zoster virus and its relationship to the pain conditions caused by shingles and postherpetic neuralgia are reviewed. The framework for the current conceptualization is Hope-Simpson’s latency hypothesis. Data from recent work in virology, neuroanatomy and epidemiology are reviewed, as is work using varicella-zoster virus-infected animals. The recent data largely confirm Hope-Simpson’s hypothesis and extend it significantly.

scholarly journals Varicella Vaccine Meningitis as a Complication of Herpes Zoster in Twice-Immunized Immunocompetent Adolescents

2020 ◽  
Vol 35 (13) ◽  
pp. 889-895 ◽  
Author(s):  
Veena Ramachandran ◽  
Stephen C. Elliott ◽  
Kathie L. Rogers ◽  
Randall J. Cohrs ◽  
Miles Weinberger ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Herpes Zoster ◽  
Varicella Zoster Virus ◽  
Varicella Vaccine ◽  
The United States ◽  
Vaccine Virus ◽  
Virus Reactivation ◽  
Wild Type ◽  
Varicella Zoster ◽  
Intravenous Acyclovir

Varicella-zoster virus vaccination is recommended for virtually all young children in the United States, Canada, and several other countries. Varicella vaccine is a live attenuated virus that retains some of its neurotropic properties. Herpes zoster caused by vaccine virus still occurs in immunized children, although the rate is much lower than in children who had wild-type varicella. It was commonly thought that 2 varicella vaccinations would protect children against the most serious complication of meningitis following herpes zoster; however, 2 meningitis cases have already been published. We now report a third case of varicella vaccine meningitis and define risk factors shared by all 3 immunized adolescents. The diagnosis in cerebrospinal fluid in this third case was verified by amplifying and sequencing portions of the viral genome, to document fixed alleles found only in the vaccine strain. Viral antibody was also detected in the cerebrospinal fluid by confocal microscopy. When compared with the other 2 cases, remarkably all 3 were 14 years old when meningitis occurred. All 3 were treated with intravenous acyclovir, with complete recovery. The adolescent in our case report also had recurrent asthma, which was treated with both prednisone tablets and beclomethasone inhaler before onset of meningitis. When the 3 cases were considered together, they suggested that immunity to varicella-zoster virus may be waning sufficiently in some twice-immunized adolescents to make them vulnerable to varicella vaccine virus reactivation and subsequent meningitis. This complication rarely happens in children after wild-type varicella.

scholarly journals Serological evidence of increased susceptibility to varicella-zoster virus reactivation or reinfection in natalizumab-treated patients with multiple sclerosis

2015 ◽  
Vol 21 (14) ◽  
pp. 1823-1832 ◽  
Author(s):  
Rebekka Kohlmann ◽  
Anke Salmen ◽  
Andrew Chan ◽  
Cornelius Knabbe ◽  
Jürgen Diekmann ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Herpes Zoster ◽  
Varicella Zoster Virus ◽  
Blood Donors ◽  
Virus Reactivation ◽  
Igg Antibody ◽  
Varicella Zoster ◽  
Neurotropic Viruses ◽  
Potential Marker ◽  
Increased Risk

Background: Serious adverse drug reactions of disease-modifying drugs in multiple sclerosis (MS) therapy may include enhanced susceptibility to reactivation of neurotropic herpes viruses like varicella-zoster virus (VZV) and the John Cunningham (JC) polyomavirus. Objective: Because symptomatic reactivation of these viruses are rare events, we determined the incidence of rises in anti-VZV IgG antibody levels as a potential marker for enhanced susceptibility to subclinical and symptomatic reactivation of neurotropic viruses. Methods: Anti-VZV IgG levels were measured in paired serum samples taken 6–8 months apart from natalizumab-treated MS patients, healthy blood donors and human immunodeficiency virus (HIV) infected patients. Results: The incidence of significant rises in anti-VZV IgG levels in natalizumab-treated MS patients was 4.26 per 100 person-years, which was significantly higher than in healthy blood donors. Retrospective evaluation of the available medical records of patients with rises of anti-VZV IgG levels did not reveal herpes zoster (i.e. shingles) manifestations. Conclusions: The increased incidence of significant rises of anti-VZV IgG levels in natalizumab-treated MS patients might indicate an association of natalizumab treatment of MS with an elevated risk of a subclinical VZV reactivation and/or reinfection events. Whether this is predictive of an increased risk of herpes zoster or even symptomatic reactivation of other neurotropic viruses remains to be determined in larger prospective studies.

Chronic Chest Wall Pain in Postherpetic Neuralgia

2018 ◽  
Author(s):  
Kenneth D. Candido ◽  
Teresa M. Kusper ◽  
Nebojsa Nick Knezevic
Keyword(s):  
Neuropathic Pain ◽  
Herpes Zoster ◽  
Varicella Zoster Virus ◽  
Chest Wall ◽  
Postherpetic Neuralgia ◽  
Early Treatment ◽  
Chemical Compounds ◽  
Skin Lesions ◽  
Varicella Zoster ◽  
Sensory Disturbances

Postherpetic neuralgia (PHN) is a debilitating condition that frequently arises after herpes zoster (HZ) caused by the varicella-zoster virus. It is characterized by severe neuropathic pain and sensory disturbances persisting after the resolution of characteristic vesicular skin lesions. Most commonly affected are the thoracic dermatomes. Trigeminal (V1), cervical, and lumbar nerves are other frequently affected sites. Early treatment shortens the duration of acute HZ and may prevent the onset of PHN. A variety of modalities are utilized to treat PHN, including chemical compounds, interventional pain techniques, and neuromodulation. HZ vaccine is recommended for individuals more than 60 years old, and it is currently the best method of averting HZ and consequent progression to PHN.

Sign in / Sign up

Export Citation Format

Share Document