Varicella-zoster virus-specific, cell-mediated immunity with interferon-gamma release assay after vaccination of college students with no or intermediate IgG antibody response

2014 ◽  
Vol 87 (2) ◽  
pp. 350-356 ◽  
Author(s):  
Kihei Terada ◽  
Yuri Itoh ◽  
Akihide Fujii ◽  
Seiko Kitagawa ◽  
Satoko Ogita ◽  
...  
Keyword(s):  
College Students ◽  
Antibody Response ◽  
Varicella Zoster Virus ◽  
Interferon Gamma ◽  
Interferon Gamma Release Assay ◽  
Cell Mediated Immunity ◽  
Specific Cell ◽  
Igg Antibody ◽  
Varicella Zoster ◽  
Release Assay

Longitudinal Change of Varicella-Zoster Virus-Specific Cell-Mediated Immunity in Hunt Syndrome and Bell’s Palsy

2014 ◽  
Vol 151 (1_suppl) ◽  
pp. P215-P215
Author(s):  
Takahiro Ichihara ◽  
Shin-Ichi Haginomori ◽  
Atsuko Mori ◽  
Atsuko Kanazawa ◽  
Akira Nishikado ◽  
...  
Keyword(s):  
Varicella Zoster Virus ◽  
Bell’S Palsy ◽  
Longitudinal Change ◽  
Cell Mediated Immunity ◽  
Specific Cell ◽  
Bell's Palsy ◽  
Varicella Zoster ◽  
Hunt Syndrome

scholarly journals Measurement of Varicella‐Zoster Virus (VZV)–Specific Cell‐Mediated Immunity: Comparison between VZV Skin Test and Interferon‐γ Enzyme‐Linked Immunospot Assay

2008 ◽  
Vol 198 (9) ◽  
pp. 1327-1333 ◽  
Author(s):  
Kay Sadaoka ◽  
Shigefumi Okamoto ◽  
Yasuyuki Gomi ◽  
Takeshi Tanimoto ◽  
Toyokazu Ishikawa ◽  
...  
Keyword(s):  
Varicella Zoster Virus ◽  
Skin Test ◽  
Interferon Γ ◽  
Cell Mediated Immunity ◽  
Specific Cell ◽  
Varicella Zoster

scholarly journals Varicella Zoster Virus in the Nervous System

F1000Research ◽  
2015 ◽  
Vol 4 ◽  
pp. 1356 ◽  
Author(s):  
Don Gilden ◽  
Maria Nagel ◽  
Randall Cohrs ◽  
Ravi Mahalingam ◽  
Nicholas Baird
Keyword(s):  
Nervous System ◽  
Varicella Zoster Virus ◽  
Clinical Laboratory ◽  
Viral Gene Expression ◽  
Neurological Complications ◽  
Viral Gene ◽  
Cell Mediated Immunity ◽  
Specific Cell ◽  
Varicella Zoster ◽  
Cranial Nerve Palsies

Varicella zoster virus (VZV) is a ubiquitous, exclusively human alphaherpesvirus. Primary infection usually results in varicella (chickenpox), after which VZV becomes latent in ganglionic neurons along the entire neuraxis. As VZV-specific cell-mediated immunity declines in elderly and immunocompromised individuals, VZV reactivates and causes herpes zoster (shingles), frequently complicated by postherpetic neuralgia. VZV reactivation also produces multiple serious neurological and ocular diseases, such as cranial nerve palsies, meningoencephalitis, myelopathy, and VZV vasculopathy, including giant cell arteritis, with or without associated rash. Herein, we review the clinical, laboratory, imaging, and pathological features of neurological complications of VZV reactivation as well as diagnostic tests to verify VZV infection of the nervous system. Updates on the physical state of VZV DNA and viral gene expression in latently infected ganglia, neuronal, and primate models to study varicella pathogenesis and immunity are presented along with innovations in the immunization of elderly individuals to prevent VZV reactivation.

Varicella-Zoster Virus-Specific Cell-Mediated Immunity in Facial Palsy: Comparison between Hunt Syndrome and Bell’s Palsy

2013 ◽  
Vol 149 (2_suppl) ◽  
pp. P239-P239
Author(s):  
Takahiro Ichihara ◽  
Shin-Ichi Haginomori ◽  
Atsuko Mori ◽  
Atsuko Kanazawa ◽  
Ryo Kawata
Keyword(s):  
Varicella Zoster Virus ◽  
Facial Palsy ◽  
Bell’S Palsy ◽  
Cell Mediated Immunity ◽  
Specific Cell ◽  
Bell's Palsy ◽  
Varicella Zoster ◽  
Hunt Syndrome

Clinical application, evaluation and analysis of influencing factors analysis of on tuberculosis ?-Interferon enzyme-linked immunosorbent assay

2021 ◽  
Vol 71 (11) ◽  
pp. 2543-2547
Author(s):  
Ning Xu ◽  
Wenlian Tu ◽  
Taicheng Jin ◽  
Rui Zheng ◽  
Xiaoqin Mao ◽  
...  
Keyword(s):  
Influencing Factors ◽  
Clinical Application ◽  
Interferon Gamma ◽  
Extrapulmonary Tuberculosis ◽  
Final Diagnosis ◽  
Enzyme Linked Immunosorbent Assay ◽  
Sputum Smear ◽  
Interferon Gamma Release Assay ◽  
Specific Cell ◽  
Release Assay

Objective: To assess sensitivity and specificity of the interferon gamma release assay test, and to pinpoint the influencing factors that should be taken care of in clinical application. Methods: The study was conducted at the First People's Hospital in the Yunnan Province of China from October 2018 to March 2019, and comprised samples collected from outpatient and inpatients. To detect mycobacterium tuberculosis, acid-fast staining on sputum smear was performed on relevant tissues suspected of extrapulmonary tuberculosis. Tuberculosis interferon gamma release assay test and pathology samples were examined. Tuberculosis-specific cell reaction assay kit was used for sampling. SysmexXN-2000 haematology analyser, VACUETTE SRS100/II and Beckman Coulter AU5800 were used to perform various analyses. Data was grouped and analysed using R statistical software. Results: Of the 960 samples, 516(53.75%) cases tested positive for tuberculosis infection and 444(46.25%) tested negative. The sensitivity of the pathological results was 86% and the specificity was 96%. The sensitivity of the interferon gamma release assay test was 95% and specificity 82%. Interferon release test, pathological results and final diagnosis showed significant comparisons (p<0.05). Significant relationships were also established for factors, such as age, interferon release quantity, lymphocyte, C-reactive protein and counts of mono-nuclear cell (p<0.05). Conclusions: Interferon gamma release assay test was found to have high consistency with pathological results and final diagnosis and can be used as a subsidiary to traditional clinical imaging and pathological judgment. Key Words: Tuberculosis, Interferon release, CRP, Hormone use. Continuous...  

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