High prevalence of anti-hepatitis E virus antibodies in blood donors from South West France

2007 ◽  
Vol 80 (2) ◽  
pp. 289-293 ◽  
Author(s):  
Jean Michel Mansuy ◽  
Florence Legrand-Abravanel ◽  
Jean Pierre Calot ◽  
Jean Marie Peron ◽  
Laurent Alric ◽  
...  
Keyword(s):  
Hepatitis E Virus ◽  
Blood Donors ◽  
Hepatitis E ◽  
South West ◽  
High Prevalence

scholarly journals In house ELISA based on recombinant ORF2 protein underline high prevalence of IgG anti-hepatitis E virus amongst blood donors in south Brazil

PLoS ONE ◽  
2017 ◽  
Vol 12 (5) ◽  
pp. e0176409 ◽  
Author(s):  
Rafael Pandolfi ◽  
Denise Ramos de Almeida ◽  
Marcelo Alves Pinto ◽  
Luiz Carlos Kreutz ◽  
Rafael Frandoloso
Keyword(s):  
Hepatitis E Virus ◽  
Blood Donors ◽  
Hepatitis E ◽  
Recombinant Orf2 Protein ◽  
Orf2 Protein ◽  
High Prevalence ◽  
South Brazil

scholarly journals Prevalence of hepatitis E virus (HEV) antibodies in Serbian blood donors

2014 ◽  
Vol 8 (10) ◽  
pp. 1322-1327 ◽  
Author(s):  
Tamaš Petrović ◽  
Diana Lupulović ◽  
Nereida Jiménez de Oya ◽  
Svetlana Vojvodić ◽  
Ana-Belén Blázquez ◽  
...  
Keyword(s):  
Hepatitis E Virus ◽  
Blood Donors ◽  
Hepatitis E ◽  
Enzyme Linked Immunosorbent Assay ◽  
Industrialized Countries ◽  
Limited Data ◽  
Genotype 3 ◽  
Serum Samples ◽  
High Prevalence ◽  
Polymerase Chain

Introduction: Hepatitis E virus (HEV) infection is rarely reported in industrialized countries, but recent studies have revealed quite variable seroprevalence rates among European populations, including blood donors. In Serbia, very limited data about HEV seroprevalence are available. This study aimed to determine the prevalence of anti-HEV IgG antibodies and HEV RNA in the sera of volunteer blood donors in Serbia. Methodology: Serum samples from 200 volunteer blood donors were tested for the presence of anti-HEV IgG by enzyme-linked immunosorbent assay (ELISA) using ORF-2 HEV genotype 3 recombinant proteins as antigen, and for the presence of HEV RNA by nested reverse transcriptase polymerase chain reaction (RT-PCR). Results: In total, 15% of the volunteer blood donors were seropositive. The prevalence increased with age; 21.5%, 14.2%, and 5.4% HEV seroprevalence rates were found in individuals older than 51 years, between 31 and 50 years, and in those younger than 30 years of age, respectively. However, no HEV RNA was detected in any of the individuals analyzed. Conclusions: The prevalence of anti-HEV IgG among blood donors as representatives of the general population is quite high in Serbia compared to data from many European countries. One of the reasons for this could be the high prevalence of HEV among Serbian pigs and the traditional consumption of piglet meat in the country. The relatively high HEV seroprevalence found among Serbian blood donors indicates the need for further investigation.

High prevalence of hepatitis E virus antibodies among blood donors in Southern Brazil

2015 ◽  
Vol 88 (2) ◽  
pp. 361-364 ◽  
Author(s):  
Ana Maria Passos-Castilho ◽  
Anne de Sena ◽  
Alexandre Geraldo ◽  
Celso Spada ◽  
Celso F.H. Granato
Keyword(s):  
Hepatitis E Virus ◽  
Blood Donors ◽  
Hepatitis E ◽  
Southern Brazil ◽  
High Prevalence

scholarly journals Seroprevalence of hepatitis E virus in risk populations and blood donors in a referral hospital in the south of Brazil

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Marisa Boff Costa ◽  
Michele Soares Gomes Gouvêa ◽  
Samira Chuffi ◽  
Gustavo Hirata Dellavia ◽  
Felipe Ornel ◽  
...  
Keyword(s):  
Low Income ◽  
Hepatitis E Virus ◽  
Blood Donors ◽  
Total Sample ◽  
Hepatitis E ◽  
Cross Sectional Study ◽  
Elisa Test ◽  
Confirmatory Test ◽  
Cross Sectional ◽  
Populations At Risk

AbstractThe prevalence of anti-hepatitis E virus (HEV) antibodies has a high heterogeneity worldwide. South American data are still scarce. The aim of this study was to evaluate the prevalence of HEV in populations at risk in comparison to blood donors (BD). A cross-sectional study was carried out in adults of different risk populations including crack users (CK), residents in a low income area (LIA), cirrhotic (CIR) and liver transplant patients (LT) compared with BD. The WANTAI HEV ELISA test was used and real-time PCR (in-house for screening and ALTONA as confirmatory test) for HEV RNA screening. A total of 400 participants were included. Anti-HEV IgG was positive in 19.5% of the total sample, reaching the highest rate in the CIR group, 22.5%, followed by CK, LT, and LIA (20%, 18.7%, and 17.5%, respectively). The prevalence found in BD individuals was of 18.7% (p = NS). Anti-HEV IgM was positive in only 1.5% of the sample (6/400). No blood or stools samples were positive for HEV RNA. The seroprevalence reported is among the highest rates ever found in Brazil. Considering the intense diagnostic investigation, data show that HEV circulation is more common that might be expected in our country.

Detection and characterisation of hepatitis E virus in naturally infected swine in Croatia

2013 ◽  
Vol 61 (4) ◽  
pp. 517-528 ◽  
Author(s):  
Zoran Lipej ◽  
Dinko Novosel ◽  
Lea Vojta ◽  
Besi Roić ◽  
Miljenko Šimpraga ◽  
...  
Keyword(s):  
Hepatitis E Virus ◽  
Age Groups ◽  
Hepatitis E ◽  
Health Concern ◽  
Rt Pcr ◽  
Animal Reservoir ◽  
Naturally Occurring ◽  
High Prevalence ◽  
Swine Herds ◽  
Bile Samples

Hepatitis E is a viral zoonotic disease infecting swine worldwide. Since pigs represent a likely animal reservoir for the hepatitis E virus, the epidemiology of naturally occurring hepatitis E was investigated in Croatian swine herds. Nearly all tested animals were seropositive for antibodies against the hepatitis E virus (55/60, 91.7%). Active infection was detected in all age groups by RT-PCR of viral RNA in serum (8/60, 13.3%) and bile samples (3/37, 8.1%), which was further confirmed by histopathological findings of characteristic lesions in the livers of the infected animals. Three new strains of hepatitis E virus were isolated from Croatian pig herds. Phylogenetic analysis using median-joining networks clustered those Croatian strains with isolates from various parts of the world, indicating their likely origin in international trade. Similarity to human isolates implies a zoonotic potential of Croatian strains, which raises a public health concern, especially in the light of the high prevalence of hepatitis E in the herds studied.

Hepatitis E Virus: Relevance in Blood Donors and Risk Groups

Vox Sanguinis ◽  
1999 ◽  
Vol 76 (2) ◽  
pp. 78-80 ◽  
Author(s):  
Maria Luisa Mateos ◽  
Cristina Camarero ◽  
Elena Lasa ◽  
Jose Luis Teruel ◽  
Nuria Mir ◽  
...  
Keyword(s):  
Hepatitis E Virus ◽  
Blood Donors ◽  
Risk Groups ◽  
Hepatitis E
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