Quality Control of Magnetic Resonance Elastography Using Percent Measurable Liver Volume Estimation

2021 ◽  
Author(s):  
David H. Ballard ◽  
Daniel R. Ludwig ◽  
Tyler J. Fraum ◽  
Amber Salter ◽  
Vamsi R. Narra ◽  
...  
Keyword(s):  
Quality Control ◽  
Magnetic Resonance ◽  
Liver Volume ◽  
Magnetic Resonance Elastography ◽  
Volume Estimation

scholarly journals Magnetic Resonance Elastography of Liver in Light Chain Amyloidosis

2019 ◽  
Vol 8 (5) ◽  
pp. 739 ◽  
Author(s):  
Sudhakar K. Venkatesh ◽  
Safa Hoodeshenas ◽  
Sandeep H. Venkatesh ◽  
Angela Dispenzieri ◽  
Morie A. Gertz ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Correlation Analysis ◽  
Partial Correlation ◽  
Pearson Correlation ◽  
Liver Volume ◽  
Liver Stiffness ◽  
Amyloid Deposition ◽  
Magnetic Resonance Elastography ◽  
Hepatic Amyloidosis ◽  
Pearson Correlation Analysis

In this paper, we present our preliminary findings regarding magnetic resonance elastography (MRE) on the livers of 10 patients with systemic amyloidosis. Mean liver stiffness measurements (LSM) and spleen stiffness measurements (SSM) were obtained. Magnetic resonance imaging (MRI) images were analyzed for the distribution pattern of amyloid deposition. Pearson correlation analysis was performed in order to study the correlation between LSM, SSM, liver span, liver volume, spleen span, spleen volume, serum alkaline phosphatase (ALP), N-terminal pro b-type natriuretic peptide (NT pro BNP), and the kappa and lambda free light chains. An increase in mean LSM was seen in all patients. Pearson correlation analysis showed a statistically significant correlation between LSM and liver volume (r = 0.78, p = 0.007) and kappa chain level (r = 0.65, p = 0.04). Interestingly, LSM did not correlate significantly with SSM (r = 0.45, p = 0.18), liver span (r = 0.57, p = 0.08), or serum ALP (r = 0.60, p = 0.07). However, LSM correlated significantly with serum ALP when corrected for liver volume (partial correlation, r = 0.71, p = 0.03) and NT pro BNP levels (partial correlation, r = 0.68, p = 0.04). MRI review revealed that amyloid deposition in the liver can be diffuse, lobar, or focal. MRE is useful for the evaluation of hepatic amyloidosis and shows increased stiffness in hepatic amyloidosis. MRE has the potential to be a non-invasive quantitative imaging marker for hepatic amyloidosis.

scholarly journals Lorentz force induced shear waves for magnetic resonance elastography applications

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Guillaume Flé ◽  
Guillaume Gilbert ◽  
Pol Grasland-Mongrain ◽  
Guy Cloutier
Keyword(s):  
Magnetic Resonance ◽  
Shear Wave ◽  
Lorentz Force ◽  
Wave Attenuation ◽  
Shear Waves ◽  
Estimation Method ◽  
Biological Tissues ◽  
Magnetic Resonance Elastography ◽  
Motion Generation ◽  
Wave Source

AbstractQuantitative mechanical properties of biological tissues can be mapped using the shear wave elastography technique. This technology has demonstrated a great potential in various organs but shows a limit due to wave attenuation in biological tissues. An option to overcome the inherent loss in shear wave magnitude along the propagation pathway may be to stimulate tissues closer to regions of interest using alternative motion generation techniques. The present study investigated the feasibility of generating shear waves by applying a Lorentz force directly to tissue mimicking samples for magnetic resonance elastography applications. This was done by combining an electrical current with the strong magnetic field of a clinical MRI scanner. The Local Frequency Estimation method was used to assess the real value of the shear modulus of tested phantoms from Lorentz force induced motion. Finite elements modeling of reported experiments showed a consistent behavior but featured wavelengths larger than measured ones. Results suggest the feasibility of a magnetic resonance elastography technique based on the Lorentz force to produce an shear wave source.

Stiffness change of the supraspinatus muscle can be detected by magnetic resonance elastography

2021 ◽  
Author(s):  
Akihisa Koga ◽  
Yoshiaki Itoigawa ◽  
Mikio Suga ◽  
Daichi Morikawa ◽  
Hirohisa Uehara ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Elastography ◽  
Supraspinatus Muscle
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