Alterations in Resting‐State Functional MRI Connectivity Related to Cognitive Changes in Intracranial Dural Arteriovenous Fistulas Before and After Embolization Treatment

2021 ◽  
Author(s):  
Sabarish Sekar ◽  
Santhosh Kumar Kannath ◽  
Sushama Ramachandran ◽  
Ramshekhar N. Menon ◽  
Bejoy Thomas
Keyword(s):  
Functional Mri ◽  
Resting State ◽  
Cognitive Changes ◽  
Arteriovenous Fistulas ◽  
Dural Arteriovenous Fistulas ◽  
Before And After ◽  
Embolization Treatment

scholarly journals Botulinum toxin injection changes resting state cerebellar connectivity in cervical dystonia

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Pavel Hok ◽  
Lenka Hvizdošová ◽  
Pavel Otruba ◽  
Michaela Kaiserová ◽  
Markéta Trnečková ◽  
...  
Keyword(s):  
Functional Mri ◽  
Resting State ◽  
Cervical Dystonia ◽  
Botulinum Neurotoxin ◽  
Botulinum Toxin Injection ◽  
Clinical Severity ◽  
Before And After ◽  
Positive Correlations ◽  
Using Data ◽  
The Right

AbstractIn cervical dystonia, functional MRI (fMRI) evidence indicates changes in several resting state networks, which revert in part following the botulinum neurotoxin A (BoNT) therapy. Recently, the involvement of the cerebellum in dystonia has gained attention. The aim of our study was to compare connectivity between cerebellar subdivisions and the rest of the brain before and after BoNT treatment. Seventeen patients with cervical dystonia indicated for treatment with BoNT were enrolled (14 female, aged 50.2 ± 8.5 years, range 38–63 years). Clinical and fMRI examinations were carried out before and 4 weeks after BoNT injection. Clinical severity was evaluated using TWSTRS. Functional MRI data were acquired on a 1.5 T scanner during 8 min rest. Seed-based functional connectivity analysis was performed using data extracted from atlas-defined cerebellar areas in both datasets. Clinical scores demonstrated satisfactory BoNT effect. After treatment, connectivity decreased between the vermis lobule VIIIa and the left dorsal mesial frontal cortex. Positive correlations between the connectivity differences and the clinical improvement were detected for the right lobule VI, right crus II, vermis VIIIb and the right lobule IX. Our data provide evidence for modulation of cerebello-cortical connectivity resulting from successful treatment by botulinum neurotoxin.

Evaluation of dural arteriovenous fistulas of cavernous sinus before and after endovascular treatment using time-resolved MR angiography

2010 ◽  
Vol 33 (2) ◽  
pp. 217-223 ◽  
Author(s):  
Shigeyuki Sakamoto ◽  
Masaaki Shibukawa ◽  
Yoshihiro Kiura ◽  
Toshinori Matsushige ◽  
Nobukazu Abe ◽  
...  
Keyword(s):  
Endovascular Treatment ◽  
Cavernous Sinus ◽  
Mr Angiography ◽  
Time Resolved ◽  
Arteriovenous Fistulas ◽  
Dural Arteriovenous Fistulas ◽  
Before And After

scholarly journals Embolization of Sacral Dural Arteriovenous Fistulas: A Case Series and Literature Review

2017 ◽  
Vol 6 (1-2) ◽  
pp. 73-81 ◽  
Author(s):  
Anthony M. Alvarado ◽  
Diogo C. Haussen ◽  
Koji Ebersole ◽  
Raul G. Nogueira ◽  
Michael G. Abraham
Keyword(s):  
Intraoperative Monitoring ◽  
Case Series ◽  
Embolic Agent ◽  
Spinal Angiography ◽  
Lower Extremity Weakness ◽  
Ethylene Vinyl Alcohol ◽  
Arteriovenous Fistulas ◽  
Dural Arteriovenous Fistulas ◽  
Embolization Treatment ◽  
Rare Location

The authors report 2 cases of sacral dural arteriovenous fistula (AVF) presenting with gradual neurologic decline characterized by progressive lower extremity weakness and bowel and bladder incontinence. Spinal angiography demonstrated a sacral dural AVF with perimedullary vein engorgement and drainage extending to the level of the cervical spine in both cases. The fistulas were completely obliterated with n-BCA (n-butyl cyanoacrylate) embolic agent in one case, and with ethylene vinyl alcohol (Onyx) in the second, resulting in improvement of the symptoms in both patients. The unique features of this case report include the rare location of the fistula's origin, the necessity for complete spinal angiography, and the use of intraoperative monitoring in one case to guide embolization treatment.

scholarly journals Evaluation before and after treatment of dural arteriovenous fistulas by carotid ultrasonography

Neurosonology ◽  
2017 ◽  
Vol 30 (3) ◽  
pp. 129-132 ◽  
Author(s):  
Emiko HISAEDA ◽  
Hirofumi SHIMADA ◽  
Toshiyasu OGATA ◽  
Toshio HIGASHI ◽  
Takaaki YAMASHITA ◽  
...  
Keyword(s):  
Carotid Ultrasonography ◽  
Arteriovenous Fistulas ◽  
Dural Arteriovenous Fistulas ◽  
Before And After

Developmental outcomes for neonatal dural arteriovenous fistulas

2009 ◽  
Vol 3 (2) ◽  
pp. 105-109 ◽  
Author(s):  
Jonathan N. Johnson ◽  
Tyler K. Hartman ◽  
William Barbaresi ◽  
Corey Raffel ◽  
Christopher E. Colby
Keyword(s):  
Cardiac Failure ◽  
Normal Development ◽  
Venous Hypertension ◽  
Neurological Deficits ◽  
Surgical Clipping ◽  
Arteriovenous Fistulas ◽  
Dural Arteriovenous Fistulas ◽  
Embolization Treatment ◽  
Male Neonate ◽  
High Output

Large dural arteriovenous malformations (DAVMs) accompanied by cardiac failure usually carry a poor prognosis with a high risk of morbidity and death. The authors report on the case of a male neonate with a massive DAVM who presented at birth with macrocephaly and high-output cardiac failure. The child initially underwent treatment with surgical clipping of the large main feeding artery. Hydrocephalus, thought to be due to venous hypertension, developed when the boy was 8 months old. The condition resolved after interventional embolization treatment. The patient did not require placement of a ventriculoperitoneal shunt. At 21 months of age, the child had near normal development without any focal neurological deficits.

scholarly journals Hemorrhage risk of cerebral dural arteriovenous fistulas following Gamma Knife radiosurgery in a multicenter international consortium

2020 ◽  
Vol 132 (4) ◽  
pp. 1209-1217 ◽  
Author(s):  
Robert M. Starke ◽  
David J. McCarthy ◽  
Ching-Jen Chen ◽  
Hideyuki Kano ◽  
Brendan J. McShane ◽  
...  
Keyword(s):  
Risk Factors ◽  
Multivariate Analysis ◽  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Latency Period ◽  
Venous Drainage ◽  
Arteriovenous Fistulas ◽  
Dural Arteriovenous Fistulas ◽  
Before And After

OBJECTIVEThe authors performed a study to evaluate the hemorrhagic rates of cerebral dural arteriovenous fistulas (dAVFs) and the risk factors of hemorrhage following Gamma Knife radiosurgery (GKRS).METHODSData from a cohort of patients undergoing GKRS for cerebral dAVFs were compiled from the International Radiosurgery Research Foundation. The annual posttreatment hemorrhage rate was calculated as the number of hemorrhages divided by the patient-years at risk. Risk factors for dAVF hemorrhage prior to GKRS and during the latency period after radiosurgery were evaluated in a multivariate analysis.RESULTSA total of 147 patients with dAVFs were treated with GKRS. Thirty-six patients (24.5%) presented with hemorrhage. dAVFs that had any cortical venous drainage (CVD) (OR = 3.8, p = 0.003) or convexity or torcula location (OR = 3.3, p = 0.017) were more likely to present with hemorrhage in multivariate analysis. Half of the patients had prior treatment (49.7%). Post-GRKS hemorrhage occurred in 4 patients, with an overall annual risk of 0.84% during the latency period. The annual risks of post-GKRS hemorrhage for Borden type 2–3 dAVFs and Borden type 2–3 hemorrhagic dAVFs were 1.45% and 0.93%, respectively. No hemorrhage occurred after radiological confirmation of obliteration. Independent predictors of hemorrhage following GKRS included nonhemorrhagic neural deficit presentation (HR = 21.6, p = 0.027) and increasing number of past endovascular treatments (HR = 1.81, p = 0.036).CONCLUSIONSPatients have similar rates of hemorrhage before and after radiosurgery until obliteration is achieved. dAVFs that have any CVD or are located in the convexity or torcula were more likely to present with hemorrhage. Patients presenting with nonhemorrhagic neural deficits and a history of endovascular treatments had higher risks of post-GKRS hemorrhage.

Sign in / Sign up

Export Citation Format

Share Document