Measurement of the Brain Volume/Liver Volume Ratio by Three‐Dimensional MRI in Appropriate‐for‐Gestational Age Fetuses and Those With Fetal Growth Restriction

2021 ◽  
Author(s):  
Kui Li ◽  
Guohui Yan ◽  
Weizeng Zheng ◽  
Jin Sun ◽  
Yu Zou
Keyword(s):  
Fetal Growth ◽  
Gestational Age ◽  
Fetal Growth Restriction ◽  
Brain Volume ◽  
Liver Volume ◽  
Three Dimensional ◽  
Volume Ratio ◽  
Growth Restriction ◽  
Appropriate For Gestational Age ◽  
The Brain

Investigating Fetal Growth Restriction and Perinatal Risks in Appropriate for Gestational Age Infants

2019 ◽  
Vol 74 (11) ◽  
pp. 631-633
Author(s):  
S. Cnattingius ◽  
M. S. Kramer ◽  
M. Norman ◽  
J. F. Ludvigsson ◽  
F. Fang ◽  
...  
Keyword(s):  
Fetal Growth ◽  
Gestational Age ◽  
Fetal Growth Restriction ◽  
Growth Restriction ◽  
Appropriate For Gestational Age ◽  
Perinatal Risks

scholarly journals P36.03: Predicting fetal growth restriction with liver volume by three-dimensional ultrasound in Korea

2008 ◽  
Vol 32 (3) ◽  
pp. 437-437
Author(s):  
Y. S. Jo ◽  
Y. Lee ◽  
S. J. Kim ◽  
G. S. R. Lee ◽  
J. C. Shin
Keyword(s):  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
Liver Volume ◽  
Three Dimensional ◽  
Growth Restriction

Preterm Preeclampsia with Severe Features: Composite Maternal and Neonatal Morbidities Associated with Fetal Growth Restriction

2018 ◽  
Vol 35 (08) ◽  
pp. 785-790 ◽  
Author(s):  
Raminder Khanagura ◽  
Heather Kregel ◽  
Farah Amro ◽  
Baha Sibai ◽  
Suneet Chauhan ◽  
...  
Keyword(s):  
Fetal Growth ◽  
Gestational Age ◽  
Pregnancy Outcomes ◽  
Fetal Growth Restriction ◽  
Multivariable Analysis ◽  
Growth Restriction ◽  
Tertiary Center ◽  
Appropriate For Gestational Age ◽  
Adverse Pregnancy ◽  
Estimated Fetal Weight

Objective The objective of this study was to compare adverse pregnancy outcomes between fetuses with estimated fetal weight (EFW) < 10 to > 10% in women with preterm preeclampsia (PE) with severe features. Materials and Methods All women with preterm PE with severe features and nonanomalous singletons with EFW were identified at a tertiary center. Women with oligohydramnios or absent/reversed umbilical Doppler velocimetry were excluded. Using multivariable analysis, we compared the composite maternal and neonatal morbidities (CMM and CNM) between those with appropriate for gestational age (AGA) fetal growth, defined as EFW at 10 to 90th versus those with fetal growth restriction (FGR), defined as EFW < 10th percentile for gestational age (GA). Results In this study, 165 patients were included; 112 had EFW at 10th to 90th percentile, and 53 had FGR. Of the 53 with FGR, 33 (62%) had EFW at 5 to 9% for GA and 20 (38%) had EFW < fifth percentile for GA. The CMM was significantly higher among women with FGR versus AGA (29 vs. 7%; p < 0.001). The CNM was significantly higher with FGR versus AGA (20 vs. 6%; p = 0.01). Conclusion Women with preterm PE with severe features and FGR, when compared with those with AGA, have significantly higher risk of CMM and CNM.

scholarly journals Differential Methylation of Syncytin-1 and 2 Distinguishes Fetal Growth Restriction from Physiologic Small for Gestational Age

2018 ◽  
Vol 08 (01) ◽  
pp. e18-e24 ◽  
Author(s):  
Sami Makaroun ◽  
Katherine Himes
Keyword(s):  
Fetal Growth ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Fetal Growth Restriction ◽  
Characteristic Curve ◽  
Receiver Operator Characteristic Curve ◽  
Growth Restriction ◽  
Genes Encoding ◽  
Appropriate For Gestational Age ◽  
Methylation Patterns

Objective The retroviral genes encoding Syncytin-1 (SYN1) and Syncytin-2 (SYN2) are epigenetically regulated, uniquely expressed in the placenta and critical to placental function. We sought to determine if placental expression and methylation patterns of SYN1 and SYN2 from pregnancies complicated by fetal growth restriction (FGR) differed from physiologic small for gestational age (SGA) and appropriate for gestational age (AGA) controls. Study Design Placental biopsies were obtained from AGA, SGA and FGR neonates delivered at >36 weeks gestation. SGA and FGR were defined as birth weight <10% with FGR additionally requiring abnormal fetal testing. We quantified DNA methylation of SYN1 and SYN2 by EpiTyper and gene expression by RT-qPCR. Results We identified 10 AGA, 9 SGA and 7 FGR placentas. There was decreased methylation in SYN1 and SYN2 in FGR relative to AGA and SGA. When the sum of SYN1 and SYN2 methylation was used for prediction of FGR from SGA, the area under the receiver operator characteristic curve was 0.9048 (0.7602, 1). Conclusion SYN1 and SYN2 methylation marks differ in FGR and SGA. We plan future studies to examine these markers in cell free DNA to determine if these methylation changes could be used as a biomarker for FGR.

Predicting fetal growth restriction with liver volume by three-dimensional ultrasound: Efficacy evaluation

2006 ◽  
Vol 32 (1) ◽  
pp. 13-17 ◽  
Author(s):  
Chiung-Hsin Chang ◽  
Chen-Hsiang Yu ◽  
Huei-Chen Ko ◽  
Chu-Ling Chen ◽  
Fong-Ming Chang
Keyword(s):  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
Liver Volume ◽  
Three Dimensional ◽  
Growth Restriction ◽  
Efficacy Evaluation

INTRAUTERINE GROWTH RETARDATION - A REVIEW ARTICLE

2018 ◽  
pp. 184-195
Author(s):  
Minh Son Pham ◽  
Vu Quoc Huy Nguyen ◽  
Dinh Vinh Tran
Keyword(s):  
Fetal Growth ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Fetal Growth Restriction ◽  
Growth Restriction ◽  
Growth Potential ◽  
National Guidelines ◽  
Intrauterine Growth ◽  
No Gold Standard

Small for gestational age (SGA) and fetal growth restriction (FGR) is difficult to define exactly. In this pregnancy condition, the fetus does not reach its biological growth potential as a consequence of impaired placental function, which may be because of a variety of factors. Fetuses with FGR are at risk for perinatal morbidity and mortality, and poor long-term health outcomes, such as impaired neurological and cognitive development, and cardiovascular and endocrine diseases in adulthood. At present no gold standard for the diagnosis of SGA/FGR exists. The first aim of this review is to: summarize areas of consensus and controversy between recently published national guidelines on small for gestational age or fetal growth restriction; highlight any recent evidence that should be incorporated into existing guidelines. Another aim to summary a number of interventions which are being developed or coming through to clinical trial in an attempt to improve fetal growth in placental insufficiency. Key words: fetal growth restriction (FGR), Small for gestational age (SGA)

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