Does Gadoterate Meglumine Cause Gadolinium Retention in the Brain of Children? A Case–Control Study

2019 ◽  
Vol 51 (5) ◽  
pp. 1471-1477 ◽  
Author(s):  
Elif Dilara Topcuoglu ◽  
Osman Melih Topcuoglu ◽  
Aslihan Semiz Oysu ◽  
Yasar Bukte
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Gadolinium Retention ◽  
Gadoterate Meglumine ◽  
The Brain ◽  
Control Study

Re: Does Gadoterate Meglumine Cause Gadolinium Retention in the Brain of Children? A Case–Control Study

2020 ◽  
Vol 52 (2) ◽  
pp. 636-637
Author(s):  
Joachim Forget ◽  
Polona Pozeg ◽  
Reto A. Meuli ◽  
Philippe Maeder
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Gadolinium Retention ◽  
Gadoterate Meglumine ◽  
The Brain ◽  
Control Study

Response to LTE “Re: Does Gadoterate Meglumine Cause Gadolinium Retention in the Brain of Children? A Case–Control Study”

2020 ◽  
Vol 52 (2) ◽  
pp. 634-635 ◽  
Author(s):  
Elif Dilara Topcuoglu ◽  
Osman Melih Topcuoglu ◽  
Aslıhan Semiz Oysu ◽  
Yasar Bukte
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Gadolinium Retention ◽  
Gadoterate Meglumine ◽  
The Brain ◽  
Control Study

scholarly journals Prerecovery liver biopsy in the brain-dead donor: A case-control study of logistics, safety, precision, and utility

2014 ◽  
Vol 20 (2) ◽  
pp. 237-244 ◽  
Author(s):  
Joseph Benton Oliver ◽  
Stephen Peters ◽  
Advaith Bongu ◽  
Abdel-Kareem Beidas ◽  
George Dikdan ◽  
...  
Keyword(s):  
Liver Biopsy ◽  
Case Control Study ◽  
Case Control ◽  
Brain Dead ◽  
The Brain ◽  
Brain Dead Donor ◽  
Control Study

Case-Control Study of Gliomas of the Brain among Workers Employed by a Texas City, Texas Chemical Plant

1983 ◽  
Vol 2 (3-4) ◽  
pp. 179-195 ◽  
Author(s):  
Sanford S. Leffingwell ◽  
Richard Waxweiler ◽  
Victor Alexander ◽  
Howard R. Ludwig ◽  
William Halperin
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Chemical Plant ◽  
The Brain ◽  
Control Study ◽  
Texas City

scholarly journals Social cognition and face processing in schizophrenia

2004 ◽  
Vol 185 (2) ◽  
pp. 169-170 ◽  
Author(s):  
Jeremy Hall ◽  
Jonathan M. Harris ◽  
Reiner Sprengelmeyer ◽  
Anke Sprengelmeyer ◽  
Andrew W. Young ◽  
...  
Keyword(s):  
Social Cognition ◽  
Face Processing ◽  
Case Control Study ◽  
Brain Regions ◽  
Case Control ◽  
Social Cues ◽  
Positive Symptoms ◽  
Study Participants ◽  
The Brain ◽  
Control Study

SummaryStudies of face processing have begun to elucidate the brain regions involved in social cognition, which include frontal and temporal regions known to be reduced in volume in schizophrenia. In this case-control study participants with schizophrenia (n=20) showed marked deficits in their ability to interpret social cues from faces, and those experiencing positive symptoms were impaired in recognising even basic facial emotions.

scholarly journals Hospital-based case control study and animal study on the relationship between nonylphenol exposure and depression

PeerJ ◽  
2021 ◽  
Vol 9 ◽  
pp. e11384
Author(s):  
Ya Luo ◽  
Weihong Xu ◽  
Wei Ou ◽  
Ting Wang ◽  
Changwei Yang ◽  
...  
Keyword(s):  
Chronic Exposure ◽  
Case Control Study ◽  
Case Control ◽  
Sucrose Preference ◽  
Control Group ◽  
Exposure Group ◽  
Monoamine Neurotransmitters ◽  
Healthy Group ◽  
The Brain ◽  
Control Study

Objectives The aim of this work is to explore the association between chronic exposure to nonylphenol (NP), a representative environmental endocrine disruptor (EED), and the risk of depression and its potential mechanism. Methods A hospital-based case control study was conducted from August to December 2018. Forty-one patients with confirmed depression and 47 healthy volunteers were recruited. In vitro, 20 rats were randomly divided into the control group (corn oil) and NP exposure group (n = 10 per group), which were gavaged at a dose of 4 mg/kg w/day for 180 days. Results The depressed patient group had higher Zung Self-Rating Depression Scale (SDS) (P < 0.001) and Self-Rating Anxiety Scale (SAS) (P < 0.001) scores than the healthy group. The serum NP level (P = 0.009) in the depressed group was higher than that in the healthy group, and the BDNF level (P = 0.001) was lower. The serum levels of monoamine neurotransmitters dopamine (DA) (P = 0.070), epinephrine (E) (P = 0.001), and noradrenaline (NE) (P = 0.000) were lower than those in the healthy group. In the sucrose preference test, the sucrose preference time for the exposure group of rats was lower than that of the control group (P < 0.001). In the forced swim test, a longer resting time was measured for the exposure group of rats as compared to the control group (P < 0.05). The level of NP (P < 0.001) in the brain tissue of the NP exposure group was higher than that in the control group, and the serum level of brain-derived neurotrophic factor (BDNF) (P = 0.004) was lower. Histopathological examination of the brain biopsies illustrated that the neuronal cells and nuclei in the hippocampus of the exposed group exhibited slight shrinkage. Conclusion Chronic exposure to NP at environmental doses will result in the accumulation of NP in the brain and blood, and induction of depression, which might be associated with the alterations in the expression levels of BDNF and monoamine neurotransmitters.

scholarly journals Smaller grey matter volumes in the anterior cingulate cortex and greater cerebellar volumes in patients with long-term remission of Cushing's disease: a case–control study

2013 ◽  
Vol 169 (6) ◽  
pp. 811-819 ◽  
Author(s):  
Cornelie D Andela ◽  
Steven J A van der Werff ◽  
J Nienke Pannekoek ◽  
Susan M van den Berg ◽  
Onno C Meijer ◽  
...  
Keyword(s):  
Anterior Cingulate Cortex ◽  
Grey Matter ◽  
Case Control Study ◽  
Case Control ◽  
Anterior Cingulate ◽  
Clinical Severity ◽  
The Brain ◽  
Control Study ◽  
Structural Brain

ObjectivePatients with long-term remission of Cushing's disease (CD) have persistent psychological and cognitive impairments. It is unknown whether, and to what extent, these impairments are accompanied by structural abnormalities in the brain. We aim to investigate structural changes in the brain in patients with predominantly long-term remission of CD and to examine whether these changes are associated with psychological and cognitive dysfunction and clinical severity.DesignA cross-sectional, case–control study.MethodsIn 25 patients with predominantly long-term remission of CD and 25 matched healthy controls, grey matter volumes in the regions of interest (hippocampus, amygdala, and anterior cingulate cortex (ACC)) and in the whole brain were examined, using 3T magnetic resonance imaging and a voxel-based morphometry approach. Psychological and cognitive functioning were assessed using validated questionnaires and clinical severity was assessed using the Cushing's syndrome severity index.ResultsCompared with controls, patients had smaller grey matter volumes of areas in the ACC (on average 14%, P<0.05) and greater volume of the left posterior lobe of the cerebellum (on average 34%, P<0.05). As expected, patients with remitted CD reported more depressive symptoms (P=0.005), more anxiety (P=0.003), more social phobia (P=0.034), more apathy (P=0.002), and more cognitive failure (P=0.023) compared with controls, but the differences in grey matter volumes were not associated with psychological or cognitive measures, nor with clinical severity.ConclusionPatients with predominantly long-term remission of CD showed specific structural brain abnormalities, in the presence of psychological dysfunction. Our data form a basis for future work aimed at elucidating the relation of the structural brain abnormalities and the sustained psychological deficits after long-term exposure to high cortisol levels.

Association between α-Klotho and Deep White Matter Lesions in the Brain: A Pilot Case Control Study Using Brain MRI

2017 ◽  
Vol 61 (1) ◽  
pp. 145-155 ◽  
Author(s):  
Nagato Kuriyama ◽  
Etsuko Ozaki ◽  
Toshiki Mizuno ◽  
Masafumi Ihara ◽  
Shigeto Mizuno ◽  
...  
Keyword(s):  
White Matter ◽  
Case Control Study ◽  
Brain Mri ◽  
White Matter Lesions ◽  
Case Control ◽  
Deep White Matter ◽  
The Brain ◽  
Control Study

Muscle fatigue in fibromyalgia is in the brain, not in the muscles: a case–control study of perceived versus objective muscle fatigue

2012 ◽  
Vol 72 (6) ◽  
pp. 963-966 ◽  
Author(s):  
Elisabeth Bandak ◽  
Kirstine Amris ◽  
Henning Bliddal ◽  
Bente Danneskiold-Samsøe ◽  
Marius Henriksen
Keyword(s):  
Muscle Fatigue ◽  
Case Control Study ◽  
Case Control ◽  
The Brain ◽  
Control Study
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