Increase in the iron content of the substantia nigra and red nucleus in multiple sclerosis and clinically isolated syndrome: A 7 Tesla MRI study

2014 ◽  
Vol 41 (4) ◽  
pp. 1065-1070 ◽  
Author(s):  
Anna I. Blazejewska ◽  
Ali M. Al-Radaideh ◽  
Sam Wharton ◽  
Su Yin Lim ◽  
Richard W. Bowtell ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Substantia Nigra ◽  
Iron Content ◽  
Red Nucleus ◽  
Clinically Isolated Syndrome ◽  
7 Tesla ◽  
7 Tesla Mri ◽  
Mri Study

Periventricular venous density in multiple sclerosis is inversely associated with T2 lesion count: a 7 Tesla MRI study

2012 ◽  
Vol 19 (3) ◽  
pp. 316-325 ◽  
Author(s):  
Tim Sinnecker ◽  
Ivan Bozin ◽  
Jan Dörr ◽  
Caspar F Pfueller ◽  
Lutz Harms ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Region Of Interest ◽  
Clinically Isolated Syndrome ◽  
7 Tesla ◽  
Cerebral Veins ◽  
Healthy Controls ◽  
Lesion Count ◽  
Small Blood Vessel ◽  
7 Tesla Mri ◽  
Multiple Sclerosis Patients

Background: Damage to venules in multiple sclerosis was first described decades ago. Today, ultrahigh magnetic field strength T2*-weighted magnetic resonance imaging (MRI) techniques depict very small cerebral veins in vivo with great anatomical detail. Objective: We aimed to investigate alterations of periventricular small blood vessel appearance in relation to T2 lesion count and distribution in multiple sclerosis and clinically isolated syndrome in comparison with healthy control subjects at 7 Tesla MRI. Methods: We investigated 38 patients (including 16 with early multiple sclerosis and seven with clinically isolated syndrome) and 22 matched healthy controls at 7 Tesla. The protocol included T2*-weighted Fast Low Angle Shot, and T2-weighted Turbo Inversion Recovery Magnitude sequences. We quantified periventricular venous density by a novel region-of-interest-based algorithm, expressing the ratio of ‘veins per region-of-interest’ as well as of ‘periventricular vascular area’. Results: Our study revealed significantly decreased venous density in multiple sclerosis patients compared with healthy controls. Venous alterations were already detectable in clinically isolated syndrome and early multiple sclerosis, although to a smaller extent. Venous density correlated inversely with periventricular and whole-brain T2 lesion count. Furthermore, we found no indication for cerebral venous congestion in multiple sclerosis. Conclusion: High spatially resolving anatomical T2*-weighted MRI revealed vascular alterations in early stages of multiple sclerosis, presumably as a part of widespread haemodynamic and metabolic alterations.

S8. Increased Locus Coeruleus Volume in Humans With Pathological Anxiety: An Ultra-High Field 7-Tesla MRI Study

2019 ◽  
Vol 85 (10) ◽  
pp. S299-S300
Author(s):  
Laurel Morris ◽  
Aaron Tan ◽  
Derek Smith ◽  
Mora Grehl ◽  
Kuang-Han Huang ◽  
...  
Keyword(s):  
Locus Coeruleus ◽  
High Field ◽  
7 Tesla ◽  
Ultra High Field ◽  
7 Tesla Mri ◽  
Mri Study ◽  
Pathological Anxiety

P4-059: Hippocampal microstructure and memory performance in Alzheimer's disease: A 7-Tesla MRI study

2011 ◽  
Vol 7 ◽  
pp. S719-S719
Author(s):  
Geoffrey Kerchner ◽  
Gayle Deutsch ◽  
Michael Zeineh ◽  
Brian Rutt
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Memory Performance ◽  
7 Tesla ◽  
7 Tesla Mri ◽  
Mri Study

scholarly journals Stress, inflammation and hippocampal subfields in depression: A 7 Tesla MRI Study

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Jonika Tannous ◽  
Beata R. Godlewska ◽  
Vaishali Tirumalaraju ◽  
Jair C. Soares ◽  
Phil J. Cowen ◽  
...  
Keyword(s):  
7 Tesla ◽  
Hippocampal Subfields ◽  
7 Tesla Mri ◽  
Mri Study

IC-P-127: Hippocampal microstructure and memory performance in Alzheimer's disease: A 7-Tesla MRI study

2011 ◽  
Vol 7 ◽  
pp. S60-S61
Author(s):  
Geoffrey Kerchner ◽  
Gayle Deutsch ◽  
Michael Zeineh ◽  
Brian Rutt
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Memory Performance ◽  
7 Tesla ◽  
7 Tesla Mri ◽  
Mri Study

3 Tesla and 7 Tesla MRI of multiple sclerosis cortical lesions

2010 ◽  
Vol 32 (4) ◽  
pp. 971-977 ◽  
Author(s):  
Emma C. Tallantyre ◽  
Paul S. Morgan ◽  
Jennifer E. Dixon ◽  
Ali Al-Radaideh ◽  
Matthew J. Brookes ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
3 Tesla ◽  
7 Tesla ◽  
Cortical Lesions ◽  
7 Tesla Mri
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