scholarly journals Reproducibility analysis of diffusion tensor indices and fiber architecture of human calf muscles in vivo at 1.5 Tesla in neutral and plantarflexed ankle positions at rest

2011 ◽  
Vol 34 (1) ◽  
pp. 107-119 ◽  
Author(s):  
Shantanu Sinha ◽  
Usha Sinha
Keyword(s):  
Diffusion Tensor ◽  
Fiber Architecture ◽  
Human Calf ◽  
Calf Muscles

scholarly journals Two-pedal ergometer for in vivo MRS studies of human calf muscles

2001 ◽  
Vol 46 (5) ◽  
pp. 1000-1005 ◽  
Author(s):  
Maria Pia Francescato ◽  
Valentina Cettolo
Keyword(s):  
Human Calf ◽  
Calf Muscles ◽  
In Vivo Mrs

Human calf muscles changes after strength training as revealed by diffusion tensor imaging

2019 ◽  
Vol 59 (5) ◽  
Author(s):  
Daniele Bruschetta ◽  
Giuseppe Anastasi ◽  
Veronica Andronaco ◽  
Filippo Cascio ◽  
Giuseppina Rizzo ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Strength Training ◽  
Diffusion Tensor ◽  
Human Calf ◽  
Calf Muscles

An exploration of diffusion tensor eigenvector variability within human calf muscles

2015 ◽  
Vol 43 (1) ◽  
pp. 190-202 ◽  
Author(s):  
Conrad Rockel ◽  
Michael D. Noseworthy
Keyword(s):  
Diffusion Tensor ◽  
Human Calf ◽  
Calf Muscles

scholarly journals High Inter-Rater Reliability of Manual Segmentation and Volume-Based Tractography in Healthy and Dystrophic Human Calf Muscle

Diagnostics ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 1521
Author(s):  
Johannes Forsting ◽  
Marlena Rohm ◽  
Martijn Froeling ◽  
Anne-Katrin Güttsches ◽  
Matthias Vorgerd ◽  
...  
Keyword(s):  
Diffusion Tensor ◽  
Neuromuscular Diseases ◽  
Healthy Controls ◽  
Manual Segmentation ◽  
Rater Reliability ◽  
Additional Information ◽  
Diffusion Parameters ◽  
Coefficients Of Variation ◽  
Human Calf ◽  
Calf Muscles

Background: Muscle diffusion tensor imaging (mDTI) is a promising surrogate biomarker in the evaluation of muscular injuries and neuromuscular diseases. Since mDTI metrics are known to vary between different muscles, separation of different muscles is essential to achieve muscle-specific diffusion parameters. The commonly used technique to assess DTI metrics is parameter maps based on manual segmentation (MSB). Other techniques comprise tract-based approaches, which can be performed in a previously defined volume. This so-called volume-based tractography (VBT) may offer a more robust assessment of diffusion metrics and additional information about muscle architecture through tract properties. The purpose of this study was to assess DTI metrics of human calf muscles calculated with two segmentation techniques—MSB and VBT—regarding their inter-rater reliability in healthy and dystrophic calf muscles. Methods: 20 healthy controls and 18 individuals with different neuromuscular diseases underwent an MRI examination in a 3T scanner using a 16-channel Torso XL coil. DTI metrics were assessed in seven calf muscles using MSB and VBT. Coefficients of variation (CV) were calculated for both techniques. MSB and VBT were performed by two independent raters to assess inter-rater reliability by ICC analysis and Bland-Altman plots. Next to analysis of DTI metrics, the same assessments were also performed for tract properties extracted with VBT. Results: For both techniques, low CV were found for healthy controls (≤13%) and neuromuscular diseases (≤17%). Significant differences between methods were found for all diffusion metrics except for λ1. High inter-rater reliability was found for both MSB and VBT (ICC ≥ 0.972). Assessment of tract properties revealed high inter-rater reliability (ICC ≥ 0.974). Conclusions: Both segmentation techniques can be used in the evaluation of DTI metrics in healthy controls and different NMD with low rater dependency and high precision but differ significantly from each other. Our findings underline that the same segmentation protocol must be used to ensure comparability of mDTI data.

Diffusion Tensor MRI of the Heart – In Vivo Imaging of Myocardial Fiber Architecture

2014 ◽  
Vol 7 (7) ◽  
Author(s):  
Martijn Froeling ◽  
Gustav J. Strijkers ◽  
Aart J. Nederveen ◽  
Steven A. Chamuleau ◽  
Peter R. Luijten
Keyword(s):  
In Vivo Imaging ◽  
Diffusion Tensor ◽  
Diffusion Tensor Mri ◽  
Fiber Architecture ◽  
Myocardial Fiber

scholarly journals In vivo diffusion tensor imaging of the human calf muscle

2006 ◽  
Vol 24 (1) ◽  
pp. 182-190 ◽  
Author(s):  
Shantanu Sinha ◽  
Usha Sinha ◽  
V. Reggie Edgerton
Keyword(s):  
Diffusion Tensor Imaging ◽  
Diffusion Tensor ◽  
Calf Muscle ◽  
Human Calf

scholarly journals Human soleus muscle architecture at different ankle joint angles from magnetic resonance diffusion tensor imaging

2011 ◽  
Vol 110 (3) ◽  
pp. 807-819 ◽  
Author(s):  
Usha Sinha ◽  
Shantanu Sinha ◽  
John A. Hodgson ◽  
Reggie V. Edgerton
Keyword(s):  
Diffusion Tensor Imaging ◽  
Diffusion Tensor ◽  
Muscle Fibers ◽  
Muscle Performance ◽  
Morphological Data ◽  
Total Force ◽  
Fiber Architecture ◽  
Cross Sectional ◽  
Specific Muscle

The orientation of muscle fibers influences the physiological cross-sectional area, the relationship between fiber shortening and aponeurosis shear, and the total force produced by the muscle. Such architectural parameters are challenging to determine particularly in vivo in multicompartment structures such as the human soleus with a complex arrangement of muscle fibers. The objective of this study was to map the fiber architecture of the human soleus in vivo at rest in both neutral and plantarflexed ankle positions using an MRI-based method of diffusion tensor imaging (DTI). Six subjects were imaged at 3 Tesla with the foot at rest in the two ankle positions. Eigenvalues, fractional anisotropy (FA), and eigenvector orientations of fibers in the different soleus subcompartments were evaluated after denoising of the diffusion tensor. The fiber architecture from DTI was similar to earlier studies based on a 3D fiber model from cadavers. The three eigenvalues of the diffusion tensor increased by ∼14% on increasing the joint plantarflexion angle in all of the soleus subcompartments, whereas FA showed a trend to decrease in the posterior and marginal soleus and to increase in the anterior soleus. The angle change in the lead eigenvector between the two foot positions was significant: ∼41° for the posterior soleus and ∼48° for the anterior soleus. Fibers tracked from the subcompartments support these changes seen in the eigenvector orientations. DTI-derived, subject-specific, muscle morphological data could potentially be used to model a more complete description of muscle performance and changes from disease.

In vivo diffusion tensor imaging of the neonatal rat brain development

2013 ◽  
Vol 44 (S 01) ◽  
Author(s):  
M Breu ◽  
D Reisinger ◽  
D Wu ◽  
Y Zhang ◽  
A Fatemi ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Brain Development ◽  
Rat Brain ◽  
Diffusion Tensor ◽  
Neonatal Rat ◽  
Neonatal Rat Brain

3D Microstructural Fiber Tracking of the Human Calf Muscles in Individuals With and Without Type 2 Diabetes during Rest and Exercise

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 632-P
Author(s):  
MASOUD EDALATI ◽  
CHRISTOPHER J. SORENSEN ◽  
MARY HASTINGS ◽  
MOHAMED A. ZAYED ◽  
MICHAEL J. MUELLER ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Fiber Tracking ◽  
Human Calf ◽  
Calf Muscles ◽  
Rest And Exercise
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