scholarly journals Diagnostic usefulness of water-to-fat ratio and choline concentration in malignant and benign breast lesions and normal breast parenchyma: An in vivo 1H MRS study

2011 ◽  
Vol 33 (4) ◽  
pp. 855-863 ◽  
Author(s):  
Sunitha B. Thakur ◽  
Sandra B. Brennan ◽  
Nicole M. Ishill ◽  
Elizabeth A. Morris ◽  
Laura Liberman ◽  
...  
Keyword(s):  
Normal Breast ◽  
Breast Lesions ◽  
1H Mrs ◽  
Breast Parenchyma ◽  
Diagnostic Usefulness ◽  
Benign Breast Lesions

In vivo post-contrast 1H-MRS evaluation of malignant and benign breast lesions: a meta-analysis

Tumor Biology ◽  
2014 ◽  
Vol 36 (1) ◽  
pp. 345-352 ◽  
Author(s):  
Jieying Tan ◽  
Li Xu ◽  
Wenqing Yao ◽  
Yun Wan ◽  
Shuqin Zhou ◽  
...  
Keyword(s):  
Meta Analysis ◽  
Breast Lesions ◽  
1H Mrs ◽  
Post Contrast ◽  
Benign Breast Lesions

Loss of heterozygosity in normal breast epithelial tissue and benign breast lesions in BRCA1/2 carriers with breast cancer

2004 ◽  
Vol 149 (1) ◽  
pp. 38-43 ◽  
Author(s):  
Luciane R Cavalli ◽  
Baljit Singh ◽  
Claudine Isaacs ◽  
Robert B Dickson ◽  
Bassem R Haddad
Keyword(s):  
Breast Cancer ◽  
Loss Of Heterozygosity ◽  
Normal Breast ◽  
Epithelial Tissue ◽  
Breast Lesions ◽  
Benign Breast Lesions ◽  
Breast Epithelial

scholarly journals Expression of VEGF in breast lesions: an immunohistochemical study

2019 ◽  
Vol 6 (1) ◽  
pp. 12
Author(s):  
Shuaeb Bhat ◽  
Tania R. P. ◽  
Saleem Hussain ◽  
Bushra Sahaf ◽  
Irfan Ansari
Keyword(s):  
Breast Cancer ◽  
Breast Tissue ◽  
Normal Breast Tissue ◽  
Genetic Alterations ◽  
Normal Breast ◽  
P Value ◽  
Breast Lesions ◽  
Chi Square ◽  
Malignant Breast ◽  
Benign Breast Lesions

Background: Breast cancer is the most frequent cancer in India. During the last few years, several investigators have focused on tumor angiogenesis as a critical step in cancer development and progression. Among these, vascular endothelial growth factor (VEGF) is emerging as a prognostic marker in patients with several type of cancer including breast cancer. The aim of the study was to analyse the expression of VEGF in human breast cancer as compared to normal breast tissue and benign breast lesions by immunohistochemistry. Also, to assess the usefulness of VEGF as a predictor of aggressiveness of breast lesions.Methods: Formalin fixed paraffin embedded sections of 10 cases of normal breast tissue, 20 cases of benign breast lesions and 20 cases of malignant breast lesions were taken up for the study and subjected to immunohistochemistry using VEGF.Results: The intensity of VEGF immunostaining in normal breast, benign and malignant breast lesions was evaluated and scoring was graded as 0, 1+, 2+, 3+ and 4+. Statistical analysis was performed with Chi-Square test and significant differences were noted between these 3 groups (p value <0.05).Conclusions:VEGF expression correlated well with the grade and stage of tumor indicating that VEGF positive tumors are biologically aggressive and are associated with poor prognosis but little is known about the implication of genetic alterations of VEGF in benign breast lesions.

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