scholarly journals High signal intensity halo around the carotid artery on maximum intensity projection images of time-of-flight MR angiography: A new sign for intraplaque hemorrhage

2008 ◽  
Vol 27 (6) ◽  
pp. 1341-1346 ◽  
Author(s):  
Yoo Jeong Yim ◽  
Yeon Hyeon Choe ◽  
Yonghyeh Ko ◽  
Sung Tae Kim ◽  
Keon Ha Kim ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Signal Intensity ◽  
Mr Angiography ◽  
Time Of Flight ◽  
Maximum Intensity Projection ◽  
High Signal Intensity ◽  
Maximum Intensity ◽  
Intraplaque Hemorrhage ◽  
High Signal ◽  
Projection Images

Assessment of necrotic core with intraplaque hemorrhage in atherosclerotic carotid artery plaque by MR imaging with 3D gradient-echo sequence in patients with high-grade stenosis

2010 ◽  
Vol 113 (4) ◽  
pp. 890-896 ◽  
Author(s):  
Tomohito Hishikawa ◽  
Koji Iihara ◽  
Naoaki Yamada ◽  
Hatsue Ishibashi-Ueda ◽  
Susumu Miyamoto
Keyword(s):  
Carotid Artery ◽  
Mr Imaging ◽  
Signal Intensity ◽  
High Signal Intensity ◽  
Necrotic Core ◽  
Intraplaque Hemorrhage ◽  
High Signal ◽  
High Grade ◽  
Gradient Echo ◽  
Mr Images

Object The aim of this study was to assess the histopathological differences between advanced atherosclerotic carotid artery (CA) plaques with signal hyperintensity on T1-weighted MR images and those without, focusing on necrotic core size and intraplaque hemorrhage (IPH). Methods Thirty-five patients scheduled for carotid endarterectomy underwent preoperative CA MR imaging using 3D inversion-recovery-based T1-weighted imaging (magnetization-prepared rapid acquisition gradient-echo [MPRAGE]). The signal intensity of the CA plaque on MPRAGE sequences was classified as “high” when the intensity was more than 200% that of adjacent muscle. A total of 96 axial MR images obtained in 35 patients were compared with corresponding histological sections from 36 excised specimens. The area of the necrotic core in histological sections was compared between specimens with and without high signal intensity on MPRAGE sequences. The IPH was histopathologically graded according to the size of the area positive for glycophorin A as revealed by immunohistochemical staining. The difference between plaques with and without high signal intensity was investigated with respect to the degree of IPH. The relationship of the severity of IPH to size of the necrotic core was also evaluated. Results The area of the necrotic core in plaques with high signal intensity on MPRAGE sequences was significantly larger than that in plaques without high signal intensity (median 51.2% [interquartile range 43.3–66.8%] vs 49.0% [33.2–57.6%], p = 0.029). Carotid artery plaques with high signal intensity had significantly more severe IPH than plaques with lower signal intensity (p < 0.0001). The severity of IPH was significantly associated with the size of the necrotic core (p < 0.0001). Conclusions Atherosclerotic CA plaques with high signal intensity on MPRAGE sequences had large necrotic cores with IPH in patients with high-grade stenosis; MPRAGE is useful for the evaluation of CA plaque progression.

High signal intensity in the dural sinuses on 3D-TOF MR angiography at 3.0 T

2010 ◽  
Vol 34 (5) ◽  
pp. 332-336 ◽  
Author(s):  
Sachiko Inano ◽  
Daisuke Itoh ◽  
Hidemasa Takao ◽  
Naoto Hayashi ◽  
Harushi Mori ◽  
...  
Keyword(s):  
Signal Intensity ◽  
Mr Angiography ◽  
High Signal Intensity ◽  
High Signal ◽  
Dural Sinuses ◽  
3.0 T

Variable tip angle slab selection pulses for carotid and cerebral time-of-flight MR angiography

1997 ◽  
Vol 38 (2) ◽  
pp. 275-280
Author(s):  
I. Ikushima ◽  
Y. Korogi ◽  
T. Hirai ◽  
M. Takahashi
Keyword(s):  
Mr Angiography ◽  
Three Dimensional ◽  
Time Of Flight ◽  
Maximum Intensity Projection ◽  
Signal Amplitude ◽  
Cerebral Vessels ◽  
Tone Pulse ◽  
Good Accord ◽  
Flow Phantom ◽  
Projection Images

Objective: to determine the optimal parameters of variable tip angle slab selection (tilted optimized nonsaturating excitation, TONE) pulses in time-of-flight MR angiography, in order to produce the best visualization of vessels distal to the entry partition. Material and Methods: the influences of the mean flip angle (MFA) and the profile tilt of the TONE pulse in three-dimensional (3D) time-of-flight MR angiography were evaluated with a mathematical modeling of the flow signal amplitude. We compared the calculated flow signals with the signals from flow-phantom models and with those from 6 normal volunteers. 3D gradient echo images (TR/TE/30/7) were acquired with a single variable of the MFA and the profile tilt. the flow velocity of the phantom was maintained at 15 cm/s. Regions of interest were measured on the source images. We also evaluated the visualization of the cerebral vessels on maximum intensity projection images obtained with and without TONE pulses in 5 other healthy volunteers. Results: the changes of flow signals in the phantom and in the volunteers were in good accord with those of the signals mathematically predicted and plotted by a computer, as each parameter was varied. the peripheral saturation was weaker at smaller MFA than at larger MFA. A greater profile tilt produced a more pronounced TONE effect than a lower one. the visualization of the peripheral cerebral vessels was markedly improved by the addition of the TONE pulse. Conclusion: Computer simulation is useful for examining the optimal TONE parameters. the TONE pulse markedly improves the visualization of the distal branches of the cerebral vessels.

scholarly journals Rare complication characterized by late-onset transient neurological symptoms without hyperperfusion after carotid artery stenting: A report of three cases

2015 ◽  
Vol 21 (1) ◽  
pp. 72-79 ◽  
Author(s):  
Yutaka Fukushima ◽  
Ichiro Nakahara ◽  
Tsuyoshi Ohta ◽  
Shoji Matsumoto ◽  
Ryota Ishibashi ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Signal Intensity ◽  
Carotid Artery Stenting ◽  
Late Onset ◽  
Rare Complication ◽  
Photon Emission ◽  
High Signal Intensity ◽  
Neurological Symptoms ◽  
High Signal ◽  
Emission Computed Tomography

We experienced a rare complication after carotid artery stenting (CAS) characterized by transient neurological symptoms with no evidence of distal emboli or hyperperfusion. Using neuroimaging, we investigated the pathogenesis of the complication that occurred after CAS in three patients who developed neurological symptoms over a period of ten hours after CAS and improved within two days. None of the three patients showed signs of fresh infarctions on diffusion-weighted imaging or hyperperfusion on single-photon emission computed tomography. However, high signal intensity was observed in the leptomeningeal zone of the cerebral hemisphere on the stent side in all three patients and in the leptomeningeal zone of the contralateral anterior cerebral artery territory in one patient. These areas were assessed using fluid-attenuated inversion recovery (FLAIR) magnetic resonance imaging without gadolinium administration. The high signal intensity in the leptomeningeal zone disappeared as the symptoms improved. Based on the transient nature of the neurological disorders and the normalization of FLAIR imaging findings in these patients, the pathogenesis of this complication might have been vasogenic edema due to vasoparalysis of the local vessels caused by the hemodynamic changes occurring after CAS.

scholarly journals Differential Diagnosis of Intraplaque Hemorrhage and Dissection on High-Resolution MR Imaging in Patients with Focal High Signal of the Vertebrobasilar Artery on TOF Imaging

Diagnostics ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1024
Author(s):  
Jung Hwan Kim ◽  
Hyo Sung Kwak ◽  
Seung Bae Hwang ◽  
Gyung Ho Chung
Keyword(s):  
High Resolution ◽  
Signal Intensity ◽  
Intensity Ratio ◽  
False Lumen ◽  
High Signal Intensity ◽  
Intraplaque Hemorrhage ◽  
High Signal ◽  
Signal Intensity Ratio ◽  
Vertebrobasilar Artery ◽  
Imaging Results

Purpose: Intraplaque hemorrhage (IPH) and dissection in the vertebrobasilar artery (VBA) on time of flight (TOF) source imaging are seen as focal eccentric high-signal intensity. The purpose of this study is to identify IPH and dissection in the VBA using high-resolution magnetic resonance imaging (HR-MRI). Methods: A total of 78 patients (VBA IPH: 55; dissection: 23) with focal high-signal intensity in the VBA on simultaneous non-contrast angiography and intraplaque hemorrhage (SNAP) of HR-MRI were included in this study. The focal high-signal intensity in the VBA on SNAP was defined as >200% than that of the adjacent muscle. We analyzed the signal intensity ratio (area of focal high signal intensity area/lumen) on TOF imaging and black blood (BB) T2-weighted imaging. Results: The VBA IPH group was older than the dissection group and had more hypertension. Signal intensity of a false lumen in patients with dissection on TOF imaging was significantly higher than that of VBA IPH (p < 0.001). The signal intensity ratio between lumen and lesion on TOF imaging was significantly higher in the dissection group (p < 0.001). The signal intensity of a false lumen in patients with dissection on BB T2-weighted imaging was significantly lower than that of VBA IPH (p < 0.001). The signal intensity ratio between lumen and lesion on BB T2–weighted imaging was significantly higher in the VBA IPH group (p < 0.001). Conclusions: TOF imaging and BB T2-weighted imaging on HR-MRI in patients with focal eccentric high-signal intensity on TOF imaging can distinguish between VBA IPH and dissection.

scholarly journals Carotid Atherosclerotic Calcification Does Not Result in High Signal Intensity in MR Imaging of Intraplaque Hemorrhage

2010 ◽  
Vol 31 (8) ◽  
pp. 1403-1407 ◽  
Author(s):  
R. Bitar ◽  
A.R. Moody ◽  
S. Symons ◽  
G. Leung ◽  
S. Crisp ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Signal Intensity ◽  
High Signal Intensity ◽  
Intraplaque Hemorrhage ◽  
High Signal

scholarly journals The joint involvement in adult onset Still's disease is characterised by a peculiar magnetic resonance imaging and a specific transcriptomic profile

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Piero Ruscitti ◽  
Antonio Barile ◽  
Onorina Berardicurti ◽  
Sonia Iafrate ◽  
Paola Di Benedetto ◽  
...  
Keyword(s):  
Signal Intensity ◽  
Clinical Characteristics ◽  
High Signal Intensity ◽  
Adult Onset Still’S Disease ◽  
Joint Involvement ◽  
High Signal ◽  
Bone Erosions ◽  
Transcriptomic Profile ◽  
Synovial Tissues ◽  
Bone Oedema

AbstractAdult onset Still's disease (AOSD) is a rare systemic autoinflammatory disease, characterised by fever, arthritis, and skin rash, and joint involvement is one of its clinical manifestations. The aims of this work were to assess joint involvement, to describe main patterns of involvement, and associated clinical characteristics. In this work, we aimed at assessing the joint involvement in AOSD by using MRI, to describe main patterns and associated clinical characteristics. In addition, we aimed at assessing the global transcriptomic profile of synovial tissues in AOSD to elucidate possible pathogenic pathways involved. We also evaluated the global transcriptomic profile of synovial tissues to elucidate possible pathogenic pathways involved in the disease. Thus, AOSD patients, who underwent to MRI exam on joints, were assessed to describe patterns of joint involvement and associated clinical characteristics. Some synovial tissues were collected for RNA-sequencing purposes. The most common MRI finding was the presence of synovitis on 60.5%, mainly in peripheral affected joints, with low to intermediate signal intensity on T1-weighted images and intermediate to high signal intensity on T2-fat-saturated weighted and STIR images. Bone oedema and MRI-bone erosions were reported on 34.9% and 25.6% MRI exams, respectively. Patients with MRI-bone erosions showed a higher prevalence of splenomegaly, a more frequent chronic disease course, lower levels of erythrocyte sedimentation rate, and ferritin. In AOSD synovial tissues, a hyper-expression of interleukin (IL)-1, IL-6, and TNF pathways was shown together with ferritin genes. In conclusion, in AOSD patients, the most common MRI-finding was the presence of synovitis, characterised by intermediate to high signal intensity on T2-fat-saturated weighted and STIR images. MRI-bone erosions and bone oedema were also observed. In AOSD synovial tissues, IL-1, IL-6, and TNF pathways together with ferritin genes resulted to be hyper-expressed.

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