scholarly journals Carotid Atherosclerotic Calcification Does Not Result in High Signal Intensity in MR Imaging of Intraplaque Hemorrhage

2010 ◽  
Vol 31 (8) ◽  
pp. 1403-1407 ◽  
Author(s):  
R. Bitar ◽  
A.R. Moody ◽  
S. Symons ◽  
G. Leung ◽  
S. Crisp ◽  
...  
2010 ◽  
Vol 113 (4) ◽  
pp. 890-896 ◽  
Author(s):  
Tomohito Hishikawa ◽  
Koji Iihara ◽  
Naoaki Yamada ◽  
Hatsue Ishibashi-Ueda ◽  
Susumu Miyamoto

Object The aim of this study was to assess the histopathological differences between advanced atherosclerotic carotid artery (CA) plaques with signal hyperintensity on T1-weighted MR images and those without, focusing on necrotic core size and intraplaque hemorrhage (IPH). Methods Thirty-five patients scheduled for carotid endarterectomy underwent preoperative CA MR imaging using 3D inversion-recovery-based T1-weighted imaging (magnetization-prepared rapid acquisition gradient-echo [MPRAGE]). The signal intensity of the CA plaque on MPRAGE sequences was classified as “high” when the intensity was more than 200% that of adjacent muscle. A total of 96 axial MR images obtained in 35 patients were compared with corresponding histological sections from 36 excised specimens. The area of the necrotic core in histological sections was compared between specimens with and without high signal intensity on MPRAGE sequences. The IPH was histopathologically graded according to the size of the area positive for glycophorin A as revealed by immunohistochemical staining. The difference between plaques with and without high signal intensity was investigated with respect to the degree of IPH. The relationship of the severity of IPH to size of the necrotic core was also evaluated. Results The area of the necrotic core in plaques with high signal intensity on MPRAGE sequences was significantly larger than that in plaques without high signal intensity (median 51.2% [interquartile range 43.3–66.8%] vs 49.0% [33.2–57.6%], p = 0.029). Carotid artery plaques with high signal intensity had significantly more severe IPH than plaques with lower signal intensity (p < 0.0001). The severity of IPH was significantly associated with the size of the necrotic core (p < 0.0001). Conclusions Atherosclerotic CA plaques with high signal intensity on MPRAGE sequences had large necrotic cores with IPH in patients with high-grade stenosis; MPRAGE is useful for the evaluation of CA plaque progression.


2012 ◽  
Vol 13 (5) ◽  
pp. 618 ◽  
Author(s):  
Suyon Chang ◽  
Man-Deuk Kim ◽  
Myungsu Lee ◽  
Mu Sook Lee ◽  
Sung Il Park ◽  
...  

2010 ◽  
Vol 40 (8) ◽  
pp. 1390-1396 ◽  
Author(s):  
Anthony R. Hart ◽  
Michael F. Smith ◽  
Alan S. Rigby ◽  
Lauren I. Wallis ◽  
Elspeth H. Whitby

Radiology ◽  
1992 ◽  
Vol 183 (1) ◽  
pp. 247-256 ◽  
Author(s):  
D Sappey-Marinier ◽  
R F Deicken ◽  
G Fein ◽  
G Calabrese ◽  
B Hubesch ◽  
...  

1994 ◽  
Vol 35 (5) ◽  
pp. 459-462 ◽  
Author(s):  
Y. Robert ◽  
J.-M. Rigot ◽  
N. Rocourt ◽  
L. Lemaitre ◽  
J. Biserte ◽  
...  

Ejaculatory duct cysts are a rare type of prostatic cysts. We report 3 cases of symptomatic ejaculatory duct cysts which have been explored by MR imaging. The MR findings were round or oval masses, medial or paramedial in the prostatic gland above the level of the verumontanum, extending into the prostatic base. They displayed a low signal intensity on T1-weighted images and high signal intensity on T2-weighted images (2 cases) or high signal intensity on both T1- and T2-weighted images (1 case). The diagnosis was confirmed by an ultrasonographically guided transperineal aspiration demonstrating spermatozoa in the cyst fluid.


1989 ◽  
Vol 13 (5) ◽  
pp. 797-802 ◽  
Author(s):  
Jerome A. Barakos ◽  
Jeffrey J. Brown ◽  
Robert J. Brescia ◽  
Charles B. Higgins

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