scholarly journals Differentiation of clinically benign and malignant breast lesions using diffusion-weighted imaging

2002 ◽  
Vol 16 (2) ◽  
pp. 172-178 ◽  
Author(s):  
Yong Guo ◽  
You-Quan Cai ◽  
Zu-Long Cai ◽  
Yuan-Gui Gao ◽  
Ning-Yu An ◽  
...  
Keyword(s):  
Diffusion Weighted Imaging ◽  
Breast Lesions ◽  
Diffusion Weighted ◽  
Malignant Breast

Effects of contrast-enhancement on diffusion weighted imaging and apparent diffusion coefficient measurements in 3-T magnetic resonance imaging of breast lesions

2017 ◽  
Vol 59 (8) ◽  
pp. 902-908
Author(s):  
Valentina Cipolla ◽  
Daniele Guerrieri ◽  
Giacomo Bonito ◽  
Simone Celsa ◽  
Carlo de Felice
Keyword(s):  
Diffusion Coefficient ◽  
Apparent Diffusion Coefficient ◽  
Diffusion Weighted Imaging ◽  
Breast Lesions ◽  
Post Contrast ◽  
Diffusion Weighted ◽  
Signed Rank ◽  
Apparent Diffusion ◽  
Malignant Breast ◽  
Adc Values

Background The effect of gadolinium-based contrast agents on diffusion-weighted imaging (DWI) measurements of breast lesions is still not clear. Purpose To investigate gadolinium effects on DWI and apparent diffusion coefficient (ADC) in breast lesions and normal parenchyma with 3 Tesla contrast-enhanced MRI. Material and Methods Pre- and post-contrast DWI (b = 0 and b = 1000 s/mm2) were acquired in 47 patients. Measured ADC values, pre- and post-contrast T2 signal intensity (T2 SI) and contrast-to-noise ratio (CNR) were compared with Wilcoxon signed-rank and rank-sum test ( P < 0.05). Results Post-contrast ADC was reduced only in malignant lesions (−34%), T2 SI was reduced both in malignant (−50%) and benign (−36%) lesions. Post-contrast CNR was reduced in all groups except for benign lesions. Conclusion Gadolinium-based contrast agent causes a significant reduction in ADC values of malignant breast lesions.

scholarly journals Utility of diffusion weighted mr in diffrentation between benign and malgnant breast lesions

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
A E E Rady ◽  
H M Sakr ◽  
Y I Abdelkhalie ◽  
A S M Sadek
Keyword(s):  
Diffusion Weighted Imaging ◽  
Breast Lesions ◽  
Adc Value ◽  
Breast Masses ◽  
Conventional Mri ◽  
Diffusion Weighted ◽  
Apparent Diffusion ◽  
Malignant Breast ◽  
Adc Values ◽  
Value Measurement

Abstract Purpose of this Study is To evaluate the role of DWI MRI in the differentiation between benign and malignant breast lesions. Methods The study included 40 patients all of them were females with positive breast lesion detected by ultrasound or mammography (between 25 and 66 years of age) referred from surgery and oncology departments. Each patient included in the study was subjected to full history taking, mammography, ultrasonography and conventional MRI sequences and Diffusion Weighted imaging and ADC value measurement. Technique was performed using a standard 1.5 Tesla unit (Acheiva, Philips). Results The study showed significant results were obtained between ADC values of benign and malignant lesions (p &lt; 0.001). Conclusion According to the results of this study we concluded that the addition of DW-MRI and ADC value measurements to the conventional MRI of the breast increased the accuracy of diagnosis and characterization of different breast masses. Also, the use of DW-MRI with ADC value measurements was found to be a valuable quantitative analysis. Keywords Breast masses– MRI – Diffusion weighted imaging Apparent diffusion coefficient.

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