scholarly journals In vivo measurement of the apparent diffusion coefficient in normal and malignant prostatic tissues using echo-planar imaging

2002 ◽  
Vol 16 (2) ◽  
pp. 196-200 ◽  
Author(s):  
Bashar Issa
Keyword(s):  
Diffusion Coefficient ◽  
Apparent Diffusion Coefficient ◽  
Echo Planar Imaging ◽  
Planar Imaging ◽  
In Vivo Measurement ◽  
Apparent Diffusion ◽  
Echo Planar

Signal-to-Noise Ratio importance in Apparent Diffusion Coefficient measurements using Diffusion-Weighted Echo-Planar-Imaging scans

2014 ◽  
Vol 4 (2) ◽  
pp. 517-525
Author(s):  
Cristiano Biagini ◽  
Martina De Michele ◽  
Andrea Pratesi ◽  
Francesco Mungai ◽  
Margherita Betti ◽  
...  
Keyword(s):  
Diffusion Coefficient ◽  
Apparent Diffusion Coefficient ◽  
Signal To Noise Ratio ◽  
Planar Imaging ◽  
Signal To Noise ◽  
Diffusion Weighted ◽  
Apparent Diffusion ◽  
Noise Ratio ◽  
Echo Planar

Purpose: To define experimental grounds for Apparent Diffusion Coefficient (ADC) measurements using Spin-Echo Diffusion-Weighted Echo-Planar (SE-DW-EPI) sequences, as a function of Signal-to-Noise Ratio (SNR).Methods: multiple multi-b SE-DW-EPI scans with the same parameters but the lipid suppression technique have been compared on water phantom with a 3T MRI equipment. The SNR has been estimated using the method of difference. Images have been analyzed manually, comparing the signal intensities at different b-values.Results: All measurements show a high repeatability and strong self-consistency. A significant dependence of the ADC on SNR has been shown, and its lowest limitto obtain reliable quantitative answers has been stated.Conclusion: ADC measurements in vivo must be carefully designed to avoid systematic errors during acquisition and post-processing due to low SNR.

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