scholarly journals The case for viral load testing in adolescents in resource-limited settings

2017 ◽  
Vol 20 ◽  
pp. e25002 ◽  
Author(s):  
Rebecca Marcus ◽  
Rashida A Ferrand ◽  
Katharina Kranzer ◽  
Linda-Gail Bekker
Keyword(s):  
Viral Load ◽  
Load Testing ◽  
Resource Limited Settings ◽  
Viral Load Testing ◽  
Resource Limited

Evaluation of two commercially available alternatives for HIV-1 viral load testing in resource-limited settings

2007 ◽  
Vol 146 (1-2) ◽  
pp. 178-187 ◽  
Author(s):  
Kim Steegen ◽  
Stanley Luchters ◽  
Nancy De Cabooter ◽  
Jacqueline Reynaerts ◽  
Kishor Mandaliya ◽  
...  
Keyword(s):  
Viral Load ◽  
Load Testing ◽  
Resource Limited Settings ◽  
Viral Load Testing ◽  
Resource Limited ◽  
Hiv 1

scholarly journals Viral load testing in a resource-limited setting: quality control is critical

2011 ◽  
Vol 14 (1) ◽  
pp. 23-23 ◽  
Author(s):  
Jane Greig ◽  
Philipp du Cros ◽  
Derryck Klarkowski ◽  
Clair Mills ◽  
Steffen Jørgensen ◽  
...  
Keyword(s):  
Quality Control ◽  
Viral Load ◽  
Resource Limited Setting ◽  
Load Testing ◽  
Viral Load Testing ◽  
Resource Limited ◽  
Limited Setting

scholarly journals Monitoring the Quality of HIV-1 Viral Load Testing through a Proficiency Testing Program Using Dried Tube Specimens in Resource-Limited Settings

2015 ◽  
Vol 53 (4) ◽  
pp. 1129-1136 ◽  
Author(s):  
Shon Nguyen ◽  
Artur Ramos ◽  
Joy Chang ◽  
Bin Li ◽  
Vedapuri Shanmugam ◽  
...  
Keyword(s):  
Viral Load ◽  
Proficiency Testing ◽  
Good Alternative ◽  
Cold Chain ◽  
Quality Assurance Program ◽  
Load Testing ◽  
Resource Limited Settings ◽  
Resource Limited ◽  
Proficiency Scores ◽  
Hiv 1

HIV-1 viral load (VL) levels are used for monitoring disease progression and antiretroviral therapy outcomes in HIV-infected patients. To assess the performance of laboratories conducting HIV-1 VL testing in resource-limited settings, the U.S. Centers for Disease Control and Prevention implemented a voluntary, free-of-charge, external quality assurance program using dried tube specimens (DTSs). Between 2010 and 2012, DTS proficiency testing (PT) panels consisting of 5 specimens were distributed at ambient temperature to participants. The results from the participants (n≥ 6) using the same assay were grouped, analyzed, and graded as acceptable within a group mean ± 3 standard deviations. Mean proficiency scores were calculated by dividing the combined PT scores by the number of testing cycles using a linear regression model. Between 2010 and 2012, the number of participants enrolled increased from 32 in 16 countries to 114 in 44 countries. A total of 78.2% of the participants reported results using 10 different VL assays. The rates of reporting of acceptable results by the participants were 96.6% for the Abbott assay, 96.3% for the Roche Cobas assay, 94.5% for the Roche Amplicor assay, 93.0% for the Biocentric assay, and 89.3% for the NucliSens assay. The overall mean proficiency scores improved over time (P= 0.024). DTSs are a good alternative specimen type to plasma specimens for VL PT programs, as they do not require cold chain transportation and can be used on PCR-based assays. Our data suggest that the CDC HIV-1 VL PT program using DTSs positively impacts the testing performance of the participants, which might translate into better and more accurate VL testing services for patients.

scholarly journals Viral Load Testing for HIVBeyond the CD4 Count

1999 ◽  
Vol 30 (2) ◽  
pp. 102-108
Author(s):  
Patricia Bereck Weikersheimer
Keyword(s):  
Viral Load ◽  
Cd4 Count ◽  
Load Testing ◽  
Viral Load Testing
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