Microwave assisted synthesis, biological activities, and in silico investigation of some benzimidazole derivatives

2020 ◽  
Vol 57 (12) ◽  
pp. 4215-4238
Author(s):  
Zeel A. Bhavsar ◽  
Prachi T. Acharya ◽  
Divya J. Jethava ◽  
Dhaval B. Patel ◽  
Mahesh S. Vasava ◽  
...  
Keyword(s):  
In Silico ◽  
Biological Activities ◽  
Benzimidazole Derivatives ◽  
Microwave Assisted Synthesis ◽  
Microwave Assisted

ChemInform Abstract: Microwave Assisted Synthesis of Some Novel Pyrazole Substituted Benzimidazoles (V) and Evaluation of Their Biological Activities.

ChemInform ◽  
2012 ◽  
Vol 43 (16) ◽  
pp. no-no ◽  
Author(s):  
R. Kalirajan ◽  
Leela Rathore ◽  
S. Jubie ◽  
B. Gowramma ◽  
S. Gomathy ◽  
...  
Keyword(s):  
Biological Activities ◽  
Microwave Assisted Synthesis ◽  
Microwave Assisted

Microwave assisted synthesis of chalcone and its polycyclic heterocyclic analogues as promising antibacterial agents: In vitro, in silico and DFT studies

2019 ◽  
Vol 1190 ◽  
pp. 77-85 ◽  
Author(s):  
Salman A. Khan ◽  
Abdullah M. Asiri ◽  
Najat Saeed M. Al-Ghamdi ◽  
Mohammad Asad ◽  
Mohie E.M. Zayed ◽  
...  
Keyword(s):  
In Silico ◽  
Antibacterial Agents ◽  
Microwave Assisted Synthesis ◽  
Dft Studies ◽  
Microwave Assisted

Microwave assisted synthesis and in silico screening of steroidal pyrazolines

2012 ◽  
Vol 23 (9) ◽  
pp. 1039-1042 ◽  
Author(s):  
Mahboob Alam ◽  
Shahab A.A. Nami ◽  
M. Parveen ◽  
Dong-Ung Lee ◽  
Soonheum Park
Keyword(s):  
In Silico ◽  
Microwave Assisted Synthesis ◽  
In Silico Screening ◽  
Microwave Assisted

Design, Microwave-Assisted Synthesis, and Spasmolytic Activity of 2-(Alkyloxyaryl)-1H-benzimidazole Derivatives as Constrained Stilbene Bioisosteres.

ChemInform ◽  
2006 ◽  
Vol 37 (51) ◽  
Author(s):  
Gabriel Navarrete-Vazquez ◽  
Hermenegilda Moreno-Diaz ◽  
Francisco Aguirre-Crespo ◽  
Ismael Leon-Rivera ◽  
Rafael Villalobos-Molina ◽  
...  
Keyword(s):  
Benzimidazole Derivatives ◽  
Microwave Assisted Synthesis ◽  
Spasmolytic Activity ◽  
Microwave Assisted

Copper-Catalyzed Microwave-Assisted Synthesis of Benzimidazole Derivatives

2014 ◽  
Vol 34 (9) ◽  
pp. 1900 ◽  
Author(s):  
Fang Ke ◽  
Jianhua Xu ◽  
Caiqin Liu ◽  
Qian Li ◽  
Wen Wu ◽  
...  
Keyword(s):  
Benzimidazole Derivatives ◽  
Microwave Assisted Synthesis ◽  
Microwave Assisted

Microwave-assisted synthesis of a novel class of imidazolylthiazolidin-4-ones and evaluation of its biological activities

2010 ◽  
Vol 14 (4) ◽  
pp. 767-776 ◽  
Author(s):  
Sachin G. Modha ◽  
Vaibhav P. Mehta ◽  
Denis Ermolat’ev ◽  
Jan Balzarini ◽  
Kristof Van Hecke ◽  
...  
Keyword(s):  
Biological Activities ◽  
Microwave Assisted Synthesis ◽  
Microwave Assisted

Microwave-assisted synthesis of bis(N-substituted thiazol-2-amine) derivatives and their biological activities

2017 ◽  
Vol 23 (5) ◽  
Author(s):  
N.H. Kumar Baba ◽  
D. Ashok ◽  
Boddu Ananda Rao ◽  
Madderla Sarasija ◽  
N.Y.S. Murthy ◽  
...  
Keyword(s):  
Biological Activities ◽  
Microwave Assisted Synthesis ◽  
Microwave Assisted

AbstractNew 4,4′-(4,6-dimethoxy-1,3-phenylene)-bis(

scholarly journals Microwave-Assisted Synthesis of Lactose Acetates with Antimicrobial, Cytotoxic, and Antiviral Properties

2021 ◽  
Vol 12 (6) ◽  
pp. 8453-8470
Keyword(s):  
Mdck Cells ◽  
Biological Activities ◽  
Antibacterial Activities ◽  
Microwave Assisted Synthesis ◽  
Resonance Spectroscopy ◽  
Antifungal Activities ◽  
Microwave Assisted ◽  
Rhizopus Sp ◽  
Coxsackievirus B1 ◽  
Hsv 1

The task of this study was to perform the "green" synthesis of lactose octaacetate through microwave irradiation and to establish their biological activities. Lactose ester was prepared after microwave-assisted esterification of lactose with acetic anhydride (yield 85-90 %). Lactose octaacetate was characterized by a high degree of acetylation (DS 3.2-3.7). The lactose esters' structure was elucidated by infrared spectroscopy and nuclear magnetic resonance spectroscopy. Lactose octaacetate showed better antifungal activities than antibacterial activities. It possessed slight to moderate antifungal activities against Aspergillus niger ATCC 1015, Penicillium sp., Rhizopus sp., Fusarium moniliforme ATCC 38932. Lactose acetates demonstrated low cytotoxicity against three cell lines: Madin-Darby bovine kidney (MDBK) cells, human epithelial type 2 (HEp-2), and Madin-Darby canine kidney (MDCK) cells. This is the first report for antiviral activity of lactose acetates against herpes simplex virus type 1 (HSV-1), influenza virus A/Panama/2007/99/H3N2 - (IAV/H3N2), PV-1 and Coxsackievirus B1. It was found that this compound showed activity with SI = 2.4 only against PV-1, but against HSV-1, IAV/H3N2, and Coxsackievirus B1 was inactive. The current study demonstrated the applications of lactose acetates as antimicrobial and antiviral substances in food, pharmaceutical, agricultural and cosmetic preparations.

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