ChemInform Abstract: Microwave Assisted Synthesis of Some Novel Pyrazole Substituted Benzimidazoles (V) and Evaluation of Their Biological Activities.

ChemInform ◽  
2012 ◽  
Vol 43 (16) ◽  
pp. no-no ◽  
Author(s):  
R. Kalirajan ◽  
Leela Rathore ◽  
S. Jubie ◽  
B. Gowramma ◽  
S. Gomathy ◽  
...  
Keyword(s):  
Biological Activities ◽  
Microwave Assisted Synthesis ◽  
Microwave Assisted

Microwave-assisted synthesis of a novel class of imidazolylthiazolidin-4-ones and evaluation of its biological activities

2010 ◽  
Vol 14 (4) ◽  
pp. 767-776 ◽  
Author(s):  
Sachin G. Modha ◽  
Vaibhav P. Mehta ◽  
Denis Ermolat’ev ◽  
Jan Balzarini ◽  
Kristof Van Hecke ◽  
...  
Keyword(s):  
Biological Activities ◽  
Microwave Assisted Synthesis ◽  
Microwave Assisted

Microwave-assisted synthesis of bis(N-substituted thiazol-2-amine) derivatives and their biological activities

2017 ◽  
Vol 23 (5) ◽  
Author(s):  
N.H. Kumar Baba ◽  
D. Ashok ◽  
Boddu Ananda Rao ◽  
Madderla Sarasija ◽  
N.Y.S. Murthy ◽  
...  
Keyword(s):  
Biological Activities ◽  
Microwave Assisted Synthesis ◽  
Microwave Assisted

AbstractNew 4,4′-(4,6-dimethoxy-1,3-phenylene)-bis(

scholarly journals Microwave-Assisted Synthesis of Lactose Acetates with Antimicrobial, Cytotoxic, and Antiviral Properties

2021 ◽  
Vol 12 (6) ◽  
pp. 8453-8470
Keyword(s):  
Mdck Cells ◽  
Biological Activities ◽  
Antibacterial Activities ◽  
Microwave Assisted Synthesis ◽  
Resonance Spectroscopy ◽  
Antifungal Activities ◽  
Microwave Assisted ◽  
Rhizopus Sp ◽  
Coxsackievirus B1 ◽  
Hsv 1

The task of this study was to perform the "green" synthesis of lactose octaacetate through microwave irradiation and to establish their biological activities. Lactose ester was prepared after microwave-assisted esterification of lactose with acetic anhydride (yield 85-90 %). Lactose octaacetate was characterized by a high degree of acetylation (DS 3.2-3.7). The lactose esters' structure was elucidated by infrared spectroscopy and nuclear magnetic resonance spectroscopy. Lactose octaacetate showed better antifungal activities than antibacterial activities. It possessed slight to moderate antifungal activities against Aspergillus niger ATCC 1015, Penicillium sp., Rhizopus sp., Fusarium moniliforme ATCC 38932. Lactose acetates demonstrated low cytotoxicity against three cell lines: Madin-Darby bovine kidney (MDBK) cells, human epithelial type 2 (HEp-2), and Madin-Darby canine kidney (MDCK) cells. This is the first report for antiviral activity of lactose acetates against herpes simplex virus type 1 (HSV-1), influenza virus A/Panama/2007/99/H3N2 - (IAV/H3N2), PV-1 and Coxsackievirus B1. It was found that this compound showed activity with SI = 2.4 only against PV-1, but against HSV-1, IAV/H3N2, and Coxsackievirus B1 was inactive. The current study demonstrated the applications of lactose acetates as antimicrobial and antiviral substances in food, pharmaceutical, agricultural and cosmetic preparations.

scholarly journals Design, Microwave-Assisted Synthesis and Biological Activities of 1,2,4-Triazol-3-Yl-Thiazolidin-4-Ones

2016 ◽  
Vol 06 (04) ◽  
Author(s):  
Monia Aouali ◽  
Fatma Masmoudi ◽  
Fatma Allouche ◽  
Laurent El Kaim ◽  
Fakher Chabchoub ◽  
...  
Keyword(s):  
Biological Activities ◽  
Microwave Assisted Synthesis ◽  
Microwave Assisted

scholarly journals Microwave-Assisted Synthesis and Biological Activities of 3,6-Disubstituted-1,2,4-triazine Derivatives

2013 ◽  
Vol 33 (10) ◽  
pp. 2178 ◽  
Author(s):  
Yingjun Li ◽  
Xin Shao ◽  
Lixin Gao ◽  
Kun Jin ◽  
Li Sheng ◽  
...  
Keyword(s):  
Biological Activities ◽  
Microwave Assisted Synthesis ◽  
Microwave Assisted ◽  
Triazine Derivatives

Microwave assisted synthesis, biological activities, and in silico investigation of some benzimidazole derivatives

2020 ◽  
Vol 57 (12) ◽  
pp. 4215-4238
Author(s):  
Zeel A. Bhavsar ◽  
Prachi T. Acharya ◽  
Divya J. Jethava ◽  
Dhaval B. Patel ◽  
Mahesh S. Vasava ◽  
...  
Keyword(s):  
In Silico ◽  
Biological Activities ◽  
Benzimidazole Derivatives ◽  
Microwave Assisted Synthesis ◽  
Microwave Assisted

Microwave assisted synthesis of some hybrid molecules derived from norfloxacin and investigation of their biological activities

2013 ◽  
Vol 67 ◽  
pp. 230-242 ◽  
Author(s):  
Meltem Yolal Mentese ◽  
Hacer Bayrak ◽  
Yıldız Uygun ◽  
Arif Mermer ◽  
Serdar Ulker ◽  
...  
Keyword(s):  
Biological Activities ◽  
Microwave Assisted Synthesis ◽  
Microwave Assisted ◽  
Hybrid Molecules

scholarly journals Microwave Assisted Improved Method for the Synthesis of Pyrazole Containing 2,4,-Disubstituted Oxazole-5-one and their Antimicrobial Activity

2008 ◽  
Vol 5 (1) ◽  
pp. 120-129 ◽  
Author(s):  
N. D. Argade ◽  
B. K. Kalrale ◽  
C. H. Gill
Keyword(s):  
Conventional Method ◽  
Antimicrobial Agents ◽  
Biological Activities ◽  
Microwave Assisted Synthesis ◽  
Antifungal Activities ◽  
Microwave Assisted ◽  
Antibacterial And Antifungal Activities ◽  
Microwave Assistance ◽  
Antibacterial And Antifungal

Disubstituted oxazol-5-one and pyrazoles are known to exhibit various biological activities. Therefore, in this work, we designed pyrazole containing 2,4-disubstituted oxazol-5-one(3a-g)as a new class of antimicrobial agents. Synthesis of titled compounds was carried out by two different methods. In the first method (conventional Method A), disubstituted oxazol-5-one(3a-g)was prepared by reacting 1-phenyl-3-p-tolyl-1H-pyrazole-4-carbaldehyde(1a-g)with hippuric acid(2)and sodium acetate, in an acetic anhydride for 2.5 - 4 h. In the second method (Method B), the above reaction was carried out under microwave assistance. Compared to the conventional method, the microwave-assisted synthesis of 3,4,5-trisubstituted imidazoles demonstrate several advantages, in terms of reaction time and overall yield. All the test compounds were evaluated forin vitroantibacterial and antifungal activities. In general, compounds with electron withdrawing groups showed good antibacterial and antifungal activities. Among the compound tested, compound(3d)showed highest activity.

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