One-Pot Multicomponent Synthesis of Novel Substituted Imidazo[1,2-a]Pyridine Incorporated Thiazolyl Coumarins and their Antimicrobial Activity

2014 ◽  
Vol 52 (3) ◽  
pp. 641-646 ◽  
Author(s):  
Rajitha Gali ◽  
Janardhan Banothu ◽  
Rajitha Bavantula
Keyword(s):  
Antimicrobial Activity ◽  
Multicomponent Synthesis ◽  
One Pot

scholarly journals Metal-free Catalyzed One-Pot Multicomponent Synthesis of (E)-3-(2-((5-(Benzylideneamino)-1,3,4-thiadiazol-2-yl)thio) Acetyl)-2H-chromen-2-one Derivatives and Their Biological Evaluation

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Shivanand Merugu ◽  
Vijaya Kumar Ponnamaneni ◽  
Ravi Varala ◽  
Syed Farooq Adil ◽  
Mujeeb Khan ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Spectral Data ◽  
Multicomponent Reaction ◽  
Biological Evaluation ◽  
Anhydrous Ethanol ◽  
Multicomponent Synthesis ◽  
One Pot ◽  
Metal Free ◽  
Substituted Benzaldehydes

A series of (E)-3-(2-((5-(benzylideneamino)-1,3,4-thiadiazol-2-yl)thio) acetyl)-2H-chromen-2-one and its derivatives (4a-h) have been obtained using a one-pot multicomponent reaction with good yields. The compounds have been synthesized from 3-(2-bromoacetyl)chromen-2-ones (1), 5-amino-1,3,4-thiadiazole-2-thiol (2), and substituted benzaldehydes (3) in anhydrous ethanol and conc. H2SO4. Subsequently, all the synthesized compounds have been screened for their antimicrobial activity and characterized by analytical and spectral data.

One-pot multicomponent synthesis of novel thiazolylhydrazone derivatives and their antimicrobial activity

2015 ◽  
Vol 41 (12) ◽  
pp. 9703-9713 ◽  
Author(s):  
G. Rajitha ◽  
V. Ravibabu ◽  
G. Ramesh ◽  
B. Rajitha ◽  
R. Jobina ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Multicomponent Synthesis ◽  
One Pot

Copper-catalyzed Convenient Synthesis and SAR Studies of Substituted-1,2,3-triazole as Antimicrobial Agents

2018 ◽  
Vol 16 (1) ◽  
pp. 3-10
Author(s):  
Aniket P. Sarkate ◽  
Kshipra S. Karnik ◽  
Pravin S. Wakte ◽  
Ajinkya P. Sarkate ◽  
Ashwini V. Izankar ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Antifungal Activity ◽  
Antimicrobial Agents ◽  
Cycloaddition Reaction ◽  
Dipolar Cycloaddition ◽  
One Pot ◽  
Triazole Derivatives ◽  
Sar Studies ◽  
Convenient Synthesis ◽  
Antibacterial And Antifungal

Background:A novel copper-catalyzed synthesis of substituted-1,2,3-triazole derivatives has been developed and performed by Huisgen 1,3-dipolar cycloaddition reaction of azides with alkynes. The reaction is one-pot multicomponent.Objective:We state the advancement and execution of a methodology allowing for the synthesis of some new substituted 1,2,3-triazole analogues with antimicrobial activity.Methods:A series of triazole derivatives was synthesized by Huisgen 1,3-dipolar cycloaddition reaction of azides with alkynes. The structures of the synthesized compounds were elucidated and confirmed by 1H NMR, IR, MS and elemental analysis. All the synthesized compounds were tested for their antimicrobial activity against a series of strains of Bacillus subtilis, Staphylococcus aureus and Escherichia coli for antibacterial activity and against the strains of Candida albicans, Aspergillus flavus and Aspergillus nigar for antifungal activity, respectively.Results and Conclusion:From the antimicrobial data, it was observed that all the newly synthesized compounds showed good to moderate level of antibacterial and antifungal activity.

Sulfamic Acid-catalyzed One-pot Multicomponent Synthesis of 5-phenyl-2- thioxo-1,2,3,5-tetrahydro-4H-pyrimido[4,5-d][1,3]thiazolo[3,2-a]pyrimidin- 4-ones

2017 ◽  
Vol 3 (3) ◽  
pp. 227-234 ◽  
Author(s):  
Sunetra Jadhav ◽  
Ajinkya Patravale ◽  
Reshma Patil ◽  
Digambar Kumbhar ◽  
Vishram Karande ◽  
...  
Keyword(s):  
Sulfamic Acid ◽  
Multicomponent Synthesis ◽  
One Pot ◽  
Acid Catalyzed

scholarly journals Clean one-pot multicomponent synthesis of pyrans using a green and magnetically recyclable heterogeneous nanocatalyst

SynOpen ◽  
2021 ◽  
Author(s):  
Mina Ghassemi ◽  
Ali Maleki
Keyword(s):  
Room Temperature ◽  
Significant Loss ◽  
Copper Ferrite ◽  
Multicomponent Synthesis ◽  
Thermo Gravimetric ◽  
Sem Images ◽  
One Pot ◽  
Three Component Reaction ◽  
Ft Ir ◽  
The One

Copper ferrite (CuFe2O4) magnetic nanoparticles (MNPs) were synthesized via thermal decomposition method and applied as a reusable and green catalyst in the synthesis of functionalized 4H-pyran derivatives using malononitrile, an aromatic aldehyde and a β-ketoester in ethanol at room temperature. Then it was characterized by Fourier transform infrared spectroscopy (FT-IR), energy-dispersive X-ray spectroscopy (EDX) analysis, scanning electron microscopy (SEM) images, thermo gravimetric and differential thermo gravimetric (TGA/DTG) analysis. The catalyst was recovered from the reaction mixture by applying an external magnet and decanting the mixture. Recycled catalyst was reused for several times without significant loss in its activity. Running the one-pot three-component reaction at room temperature, no use of eternal energy source and using a green solvent provide benign, mild, and environmentally friendly reaction conditions; as well, ease of catalyst recovering, catalyst recyclability, no use of column chromatography and good to excellent yields are extra advantages of this work.

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