Beneficial effect of D-allose for isolated islet culture prior to islet transplantation

2015 ◽  
Vol 23 (1) ◽  
pp. 37-42 ◽  
Author(s):  
Hirotaka Kashiwagi ◽  
Eisuke Asano ◽  
Chisato Noguchi ◽  
Li Sui ◽  
Akram Hossain ◽  
...  
Keyword(s):  
Beneficial Effect ◽  
Islet Transplantation ◽  
Islet Culture

Pretransplant Islet Culture: A Comparison of Four Serum-Free Media Using a Murine Model of Islet Transplantation

2005 ◽  
Vol 37 (8) ◽  
pp. 3446-3449 ◽  
Author(s):  
J. Carter ◽  
S. Karmiol ◽  
M. Nagy ◽  
R. McElreath ◽  
C. Calloway ◽  
...  
Keyword(s):  
Islet Transplantation ◽  
Murine Model ◽  
Serum Free ◽  
Islet Culture ◽  
Free Media

Low-Temperature Preservation of Isolated Islets is Superior to Conventional Islet Culture Before Islet Transplantation

2010 ◽  
Vol 89 (1) ◽  
pp. 47-54 ◽  
Author(s):  
Hirofumi Noguchi ◽  
Bashoo Naziruddin ◽  
Andrew Jackson ◽  
Masayuki Shimoda ◽  
Tetsuya Ikemoto ◽  
...  
Keyword(s):  
Low Temperature ◽  
Islet Transplantation ◽  
Isolated Islets ◽  
Islet Culture

scholarly journals Islet Culture/Preservation before Islet Transplantation

Cell Medicine ◽  
2015 ◽  
Vol 8 (1-2) ◽  
pp. 25-29 ◽  
Author(s):  
Hirofumi Noguchi ◽  
Chika Miyagi-Shiohira ◽  
Kiyoto Kurima ◽  
Naoya Kobayashi ◽  
Issei Saitoh ◽  
...  
Keyword(s):  
Islet Transplantation ◽  
Islet Culture

scholarly journals Pancreas Preservation by the Two-Layer Method: Does it Have a Beneficial Effect Compared with Simple Preservation in University of Wisconsin Solution?

2009 ◽  
Vol 18 (5-6) ◽  
pp. 497-504 ◽  
Author(s):  
Hirofumi Noguchi ◽  
Marlon F. Levy ◽  
Naoya Kobayashi ◽  
Shinichi Matsumoto
Keyword(s):  
Beneficial Effect ◽  
Islet Transplantation ◽  
Large Scale ◽  
Islet Isolation ◽  
University Of Wisconsin ◽  
Layer Method ◽  
Human Islet Transplantation ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

A large number of reports have shown that the two-layer method (TLM), which employs oxygenated perfluorochemical (PFC) and University of Wisconsin (UW) solution, is superior to simple cold storage in UW in islet transplantation. However, two recent large-scale studies showed no beneficial effect of TLM compared with UW storage in human islet transplantation. We reevaluated the effect of TLM by following three groups: group 1: UW simple storage; group 2: TLM performed by multiorgan procurement teams (not specialists of islet isolation); and group 3: TLM performed by specialists of islet isolation (Noguchi and Matsumoto). There were no significant differences between groups 1 and 2, whereas islet yields were significantly higher in group 3 compared with either group 1 or 2. Our data suggest that exact, complete performance of TLM could improve the outcome of islet isolation and transplantation. In this review, we describe the mechanisms of the TLM, the procedure of preoxygenated TLM, and the several possibilities for the reasons of the discrepancy.

Supplementation of Islet Culture Medium with Insulin May Have a Beneficial Effect on Islet Secretory Function

Pancreas ◽  
2001 ◽  
Vol 22 (1) ◽  
pp. 72-74 ◽  
Author(s):  
Heather Clayton ◽  
Julie Turner ◽  
Sue Swift ◽  
Roger James ◽  
Peter Bell
Keyword(s):  
Beneficial Effect ◽  
Culture Medium ◽  
Secretory Function ◽  
Islet Culture

scholarly journals Beneficial Effect of Insulin Treatment on Islet Transplantation Outcomes in Akita Mice

PLoS ONE ◽  
2014 ◽  
Vol 9 (4) ◽  
pp. e95451 ◽  
Author(s):  
Kazuhide Kikawa ◽  
Daisuke Sakano ◽  
Nobuaki Shiraki ◽  
Tomonori Tsuyama ◽  
Kazuhiko Kume ◽  
...  
Keyword(s):  
Beneficial Effect ◽  
Islet Transplantation ◽  
Insulin Treatment ◽  
Akita Mice ◽  
Transplantation Outcomes

scholarly journals Long-Term Beneficial Effect of Islet Transplantation on Diabetic Macro-/Microangiopathy in Type 1 Diabetic Kidney-Transplanted Patients

Diabetes Care ◽  
2003 ◽  
Vol 26 (4) ◽  
pp. 1129-1136 ◽  
Author(s):  
P. Fiorina ◽  
F. Folli ◽  
F. Bertuzzi ◽  
P. Maffi ◽  
G. Finzi ◽  
...  
Keyword(s):  
Beneficial Effect ◽  
Islet Transplantation ◽  
Diabetic Kidney

Microstructures of Ti-1.5 w/o Ni Alloys with Mo and A1 Additions

1975 ◽  
Vol 33 ◽  
pp. 54-55
Author(s):  
Anna C. Fraker
Keyword(s):  
Corrosion Resistance ◽  
Beneficial Effect ◽  
Crevice Corrosion ◽  
Local Corrosion ◽  
Precipitate Size ◽  
Ni Alloys

Small amounts of nickel are added to titanium to improve the crevice corrosion resistance but this results in an alloy which has sheet fabrication difficulties and is subject to the formation of large Ti2Ni precipitates. These large precipitates can serve as local corrosion sites; but in a smaller more widely dispersed form, they can have a beneficial effect on crevice corrosion resistance. The purpose of the present work is to show that the addition of a small amount of Mo to the Ti-1.5Ni alloy reduces the Ti2Ni precipitate size and produces a more elongated grained microstructure. It has recently been reported that small additions of Mo to Ti-0.8 to lw/o Ni alloys produce good crevice corrosion resistance and improved fabrication properties.

On the role of tin underlays for the prevention of thermal grooving in thin gold films

1986 ◽  
Vol 44 ◽  
pp. 732-733
Author(s):  
Jin Young Kim ◽  
R. E. Hummel ◽  
R. T. DeHoff
Keyword(s):  
Thin Film ◽  
Free Surface ◽  
Grain Boundary ◽  
Beneficial Effect ◽  
Failure Mechanism ◽  
Failure Mechanisms ◽  
Distinct Advantage ◽  
Gold Films ◽  
Gold Thin Film

Gold thin film metallizations in microelectronic circuits have a distinct advantage over those consisting of aluminum because they are less susceptible to electromigration. When electromigration is no longer the principal failure mechanism, other failure mechanisms caused by d.c. stressing might become important. In gold thin-film metallizations, grain boundary grooving is the principal failure mechanism.Previous studies have shown that grain boundary grooving in gold films can be prevented by an indium underlay between the substrate and gold. The beneficial effect of the In/Au composite film is mainly due to roughening of the surface of the gold films, redistribution of indium on the gold films and formation of In2O3 on the free surface and along the grain boundaries of the gold films during air annealing.

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