scholarly journals Effect of horizontal margin status and risk of local recurrence after endoscopic submucosal dissection for superficial esophageal cancer

JGH Open ◽  
2020 ◽  
Vol 4 (2) ◽  
pp. 160-165 ◽  
Author(s):  
Hiromu Fukuda ◽  
Ryu Ishihara ◽  
Yusaku Shimamoto ◽  
Mitsuhiro Kono ◽  
Kentaro Nakagawa ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Local Recurrence ◽  
Endoscopic Submucosal Dissection ◽  
Margin Status ◽  
Superficial Esophageal Cancer ◽  
Submucosal Dissection ◽  
Horizontal Margin

scholarly journals ENDOSCOPIC SUBMUCOSAL DISSECTION WITH CIRCUMFERENTIAL INCISION VERSUS TUNNELING METHOD FOR TREATMENT OF SUPERFICIAL ESOPHAGEAL CANCER

2021 ◽  
Author(s):  
Tarso Magno Leite RIBEIRO ◽  
Vitor N ARANTES ◽  
Jonas Augusto RAMOS ◽  
Peter V DRAGANOV ◽  
Dennis YANG ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Local Recurrence ◽  
Adverse Events ◽  
Endoscopic Submucosal Dissection ◽  
Curative Resection ◽  
R0 Resection ◽  
Resection Rate ◽  
Superficial Esophageal Cancer ◽  
En Bloc ◽  
Submucosal Dissection

ABSTRACT BACKGROUND: Endoscopic submucosal dissection (ESD) of esophageal superficial neoplasm is associated with a high en bloc R0 resection rate and low recurrence. OBJECTIVE: We aim to compare the performance and clinical outcomes of ESD via ESD after circumferential incision (ESD-C) versus submucosal tunneling (ESD-T). METHODS: Single-center retrospective analysis of all consecutive patients who underwent ESD for superficial esophageal cancer, between 2009 and 2018. ESD-T was defined as the technique of making the mucosal incisions followed by submucosal tunneling in the oral to anal direction. ESD-C consisted of completing a circumferential incision followed by ESD. Main study outcomes included en bloc and R0 resection rates. Secondary outcomes included procedural characteristics, curative resection rate, local recurrence and adverse events. RESULTS: A total of 65 procedures (23 ESD-T and 42 ESD-C) were performed for ESCC (40; 61.5%) and BE-neoplasia (25; 38.5%). There were no statistically significant differences between patients who underwent ESD-T versus ESD-C in en bloc (91.3% vs 100%, P=0.12), R0 (65.2% vs 78.6%, P=0.24), curative resection rates (65.2% vs 73.8%, P=0.47) and mean procedure time (118.7 min with vs 102.4 min, P=0.35). Adverse events for ESD-T and ESD-C were as follows: bleeding (0 versus 2.4%; P=0.53), perforation (4.3% vs 0; P=0.61), esophageal stricture (8.7% versus 9.5%; P=0.31). Local recurrence was encountered in 8.7% after ESD-T and 2.4% after ESD-C (P=0.28) at a mean follow-up of 8 and 2.75 years, respectively (P=0.001). CONCLUSION: ESD-T and ESD-C appear to be equally effective with similar safety profiles for the management of superficial esophageal neoplasms.

Predictors of technical difficulty during endoscopic submucosal dissection of superficial esophageal cancer

2018 ◽  
Vol 33 (9) ◽  
pp. 2909-2915 ◽  
Author(s):  
Hiromasa Hazama ◽  
Masaki Tanaka ◽  
Naomi Kakushima ◽  
Yohei Yabuuchi ◽  
Masao Yoshida ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Endoscopic Submucosal Dissection ◽  
Technical Difficulty ◽  
Superficial Esophageal Cancer ◽  
Submucosal Dissection

Evaluation of esophageal motility after endoscopic submucosal dissection for superficial esophageal cancer

2015 ◽  
Vol 27 (10) ◽  
pp. 1187-1192 ◽  
Author(s):  
Kazuya Takahashi ◽  
Manabu Takeuchi ◽  
Yuichi Sato ◽  
Hiroki Sato ◽  
Kenichi Mizuno ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Endoscopic Submucosal Dissection ◽  
Esophageal Motility ◽  
Superficial Esophageal Cancer ◽  
Submucosal Dissection
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